ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Metabolic complications"

  • 2018 American Transplant Congress

    Greater Susceptibility for Metabolic Syndrome in Pediatric Transplant Recipients – A Case-Control Study

    R. Bloete,1 N. Memaran,1 B. Borchert-Mörlins,1 D. Thurn,1 E. Bauer,1 R. Büscher,2 J. Oh,3 B. Schmidt,4 A. Melk.1

    1Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hanover, Germany; 2Department of Pediatric Nephrology, University Hospital Essen, Essen, Germany; 3Department of Pediatric Nephrology, University Medical Center Hamburg-Eppendorf, Hamburg, Germany; 4Department of Nephrology, Hannover Medical School, Hanover, Germany.

    Introduction. Metabolic syndrome not only contributes to an increased risk for cardiovascular sequelae but is also associated with impaired graft function and lower graft survival…
  • 2018 American Transplant Congress

    Prevalence of Abnormal Hemoglobin A1C in Pediatric Kidney Transplant Recipients

    A. Serluco,1 R. Liverman,1 R. George,1,2 R. Garro.1,2

    1Children's Healthcare of Atlanta, Atlanta, GA; 2Department of Pediatric Nephrology, Emory University, Atlanta, GA.

    Background: The incidence of new-onset diabetes after kidney transplantation (NODAT) in the pediatric population has not been well characterized. Early recognition of glucose intolerance may…
  • 2018 American Transplant Congress

    Factors Related to Suboptimal Recovery of Renal Function after Living Donor Nephrectomy

    S. Nishida, K. Kinoshida, K. Tanaka, Y. Hidaka, S. Hamanoue, C. Kawabata, M. Toyoda, A. Inadome, S. Uekihara, S. Yamanaga.

    Japanease Red Cross Kumamoto Hospital, Kidney Center, Kumamoto, Japan.

    Introduction:Renal function of the living donor usually recovers to 60~70 percent of baseline function by compensatory hypertrophy mechanism. However, the degree of this compensatory hypertrophy…
  • 2018 American Transplant Congress

    Kidney Transplant Rejection is Associated with Robust and Prolonged Bioenergetic Reprogramming and Metabolic Maladaptation

    A. Zmijewska, J. Zmijewski, J. Chen, R. Mannon.

    Medicine, University of Alabama at Birmingham, Birmingham, AL.

    Introduction: Metabolic plasticity and mitochondrial bioenergetic homeostasis are altered due to a organ ischemia. However, the impact of the alloimmune response on the allograft is…
  • 2018 American Transplant Congress

    Metformin Use after Kidney Transplantation: A Safe Option in Carefully Selected Patients

    F. Koraishy,1 L. Vest,1 Z. Zhang,1 M. Schnitzler,1 V. Dharnidharka,2 D. Axelrod,3 R. Ouseph,1 A. Naik,4 N. Lam,5 H. Randall,1 T. Alhamad,2 D. Segev,3 D. Brennan,3 B. Kasiske,6 G. Hess,7 K. Lentine.

    1Saint Louis Univ, St. Louis; 2Washington Univ, St. Louis; 3Lahey Clinic, Burlington; 4Univ Michigan, Ann Arbor; 5Univ Alberta, Edmonton; 6Johns Hopkins, Baltimore; 7Hennepin County, Minneapolis; 8Symphony Health, Conshohocken.

    Recent guidelines support metformin as a therapeutic option in diabetic patients with mild to moderate renal insufficiency. The frequency and outcomes of metformin use in…
  • 2018 American Transplant Congress

    New Onset Diabetes after Kidney Transplant: Comparisons of Risks Associated with Various Steroid-Containing Calcineurin Inhibitor and Sirolimus Regimens

    A. Santos, Jr.,1 M. Casey,1 K. Alquadan,1 X. Wen,2 C. Chen,3 A. Gutierrez-Mena,1 K. Womer.1

    1College of Medicine, Univ. of Florida, Gainesville, FL; 2College of Pharmacy, Univ. of Rhode Island, Kingston, RI; 3College of Pharmacy, Univ. of Florida, Gainesville, FL.

    INTRODUCTION: We aimed to examine the risk of new onset diabetes after transplant (NODAT) associated with the following maintenance immunosuppression regimens in kidney transplant recipients…
  • 2018 American Transplant Congress

    Brain Death Conditions Intensify Inflammation and Impair Metabolic Gene Expression

    L. Zitur, P. Chlebeck, S. Odorico, T. Zens, J. Danobeitia, M. Eerhart, J. Reyes, A. D'Alessandro, K. Brunner, S. Capuano, L. Fernandez.

    University of Wisconsin, Madison.

    Rationale: Inflammation observed in Brain Death (BD) donors is linked to reduced graft function and survival compared to living donors (LD). Detailed analyses of non-human…
  • 2017 American Transplant Congress

    Effect of Everolimus-Based Immunosuppressive Regimen on New Onset of Diabetes After Kidney Transplantation – A 24 Month Subanalysis from the ELEVATE Study.

    H. Holdaas,1 S. Chadban,1 J. de Fijter,1 L. Rostaing,1 U. Mancilla,1 P. Lopez,2 G. Bader,2 J. Cruzado,1 M. van der Giet.1

    1ELEVATE Study Group, Oslo, Norway; 2Novartis Pharma AG, Basel, Switzerland

    Purpose: New onset diabetes after transplantation (NODAT) is a common metabolic complication which affects long-term patient survival and graft outcomes. Most of the immunosuppressive drugs…
  • 2017 American Transplant Congress

    Kidney Transplant Recipient Intermediate and Long Term Outcomes for Living Donor Gifted Lithiasis.

    S. Doshi, M. Yaqub, T. Taber, M. Mujtaba, D. Mishler, O. Adebiyi, C. Sundaram, J. Powelson, A. Sharfuddin.

    Indiana University Health, Indianapolis

    BACKGROUND: Nephrolithiasis is considered at least a relative contraindication to living donor nephrectomy due to the potential for adverse outcomes of recurrence, obstruction and infection.…
  • 2017 American Transplant Congress

    Obesity Predicts New-Onset Diabetes After Live Kidney Donation.

    K. Lentine,1 A. Naik,2 N. Lam,3 M. Schnitzler,1,6 H. Xiao,1 D. Axelrod,4 G. Hess,5 B. Kasiske,6 A. Garg,7 S. Gustafson,6 D. Brennan,8 D. Segev.9,6

    1St. Louis Univ, St. Louis; 2U Michigan, Ann Arbor; 3U Alberta, Edmonton, Canada; 4E Carolina Univ, Greenville; 5Symphony Health, Philadelphia; 6Scientific Registry of Transplant Recipients, Minneapolis; 7Western Univ, London, Canada; 8Washington Univ, St. Louis; 9Johns Hopkins, Baltimore

    End-stage renal disease is uncommon in living kidney donors (LKD), but recent data suggest that most kidney failure developing late after donation is due to…
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