2019 American Transplant Congress
Comparison of Two Glucagon-Like-Peptide-1 Analogs (GLP -1) Dulaglutide vs Liraglutide for the Management of Diabetes in Solid Organ Transplant (SOT)
Ohio State University, Columbus, OH
*Purpose: Poorly controlled Type-2 diabetes is an important contributor to graft dysfunction, and cardiovascular morbidity in the SOT. GLP-1-analog has been widely used in the…2019 American Transplant Congress
Comparison of Simultaneous Pancreas kidney Transplantation to Kidney Transplantation Alone for Type 2 Diabetes with End Stage Renal Disease
Kidney&Pancreas Transplant, Tianjin First Center Hospital, Tianjin, China
*Purpose: To compare the clinic outcomes of simultaneous pancreas-kidney transplantation (SPK) with kidney transplantation alone (KTA) in Type 2 Diabetes patients with ESRD.*Methods: 97 type…2019 American Transplant Congress
An Immediate and Persistent Post-Reperfusion Metabolic Collapse Precedes Delayed Graft Function (DGF)
Surgery, Leiden University Medical Center, Leiden, Netherlands
*Purpose: Delayed graft function (DGF) is the manifestation of ischemia reperfusion injury (IRI) in the context of kidney transplantation. Despite clear preclinical successes, a proven…2019 American Transplant Congress
The Use of High Volume Perioperative Normal Saline Increases the Risk of Delayed Graft Function after Kidney Transplantation
*Purpose: Metabolic and physiologic effects of high volume perioperative Normal Saline (NS) resuscitation are well described, but the impact on delayed graft function (DGF) remains…2019 American Transplant Congress
Lower Extremity Impairment and Frailty among Adults with Diabetes Awaiting Kidney Transplantation
*Purpose: Frailty and lower extremity impairment, both indicators of poor physical performance, are predictive of all-cause mortality among patients awaiting kidney transplantation (KT). Diabetes, the…2018 American Transplant Congress
Kidney Transplant Rejection is Associated with Robust and Prolonged Bioenergetic Reprogramming and Metabolic Maladaptation
Medicine, University of Alabama at Birmingham, Birmingham, AL.
Introduction: Metabolic plasticity and mitochondrial bioenergetic homeostasis are altered due to a organ ischemia. However, the impact of the alloimmune response on the allograft is…2018 American Transplant Congress
Metformin Use after Kidney Transplantation: A Safe Option in Carefully Selected Patients
Recent guidelines support metformin as a therapeutic option in diabetic patients with mild to moderate renal insufficiency. The frequency and outcomes of metformin use in…2018 American Transplant Congress
New Onset Diabetes after Kidney Transplant: Comparisons of Risks Associated with Various Steroid-Containing Calcineurin Inhibitor and Sirolimus Regimens
INTRODUCTION: We aimed to examine the risk of new onset diabetes after transplant (NODAT) associated with the following maintenance immunosuppression regimens in kidney transplant recipients…2018 American Transplant Congress
Brain Death Conditions Intensify Inflammation and Impair Metabolic Gene Expression
University of Wisconsin, Madison.
Rationale: Inflammation observed in Brain Death (BD) donors is linked to reduced graft function and survival compared to living donors (LD). Detailed analyses of non-human…2018 American Transplant Congress
Metabolic Complications 10-Years after Kidney Transplant
Background: Improving long-term outcomes is an important but unmet need after kidney transplant. Protocol renal allograft biopsies taken 10-years after transplant frequently show diabetic nephropathy…
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