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American Transplant Congress abstracts

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Articles tagged "Malignancy"

  • 2016 American Transplant Congress

    Age Adapted Immunosuppression for Elderly Kidney Allograft Recipients: Balancing Risks for Cancer versus Rejection.

    F. Jackson-Spence,1 H. Gillott,1 S. Tahir,1 F. Evison,2 J. Nath,3 A. Sharif.3

    1University of Birmingham Medical School, Birmingham, United Kingdom; 2Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

    Introduction Cancer is a growing cause of morbidity and mortality after kidney transplantation, driven by immunosuppression. Age is one of the strongest risk factors for…
  • 2016 American Transplant Congress

    A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).

    D. Kaul,1 S. Tlusty,2 A. Wilk,2 C. Wolfe.1

    1OPTN Ad Hoc Disease Transmission Advisory Committee, Richmond, VA; 2United Network for Organ Sharing, Richmond, VA.

    Intro: The OPTN DTAC evaluates potential donor derived transmission events (PDDTE), including infections & malignancies, to assess for donor transmitted events.Methods: Reports of unexpected PDDTE…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Malignancy (PTM) After Pediatric Kidney Transplantation (PKTx).

    O. Serrano,1 A. Bangdiwala,2 D. Vock,2 W. Payne,1 T. Dunn,1 S. Chinnakotla,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas,1 B. Chavers.3

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics, Univ. of Minnesota, Minneapolis, MN; 3Pediatrics, Univ. of Minnesota, Minneapolis, MN.

    PURPOSE: Post-transplant immunosuppression is associated with an increase in cancer rates. To date, the long-term incidence of PTM among PKTx recipients has not been well-characterized.METHODOLOGY:…
  • 2016 American Transplant Congress

    The Heterogenous Genomic Landscape of Unresectable Hepatoblastoma Requiring Liver Transplantation: Prognostic Implications.

    M. Ningappa, B. Higgs, S. Ranganathan, C. Ashokkumar, R. Sindhi.

    Surgery, Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh, Pittsburgh, PA.

    Background: Hepatoblastoma, the most common pediatric liver malignancy, is cured by chemotherapy and surgical resection. Locally invasive/multifocal tumors require liver transplantation (LTx). A unique tumor…
  • 2015 American Transplant Congress

    Donor Derived Transmission Events in 2014: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC)

    D. Kaul,1 S. Covington,2 S. Taranto,2 M. Green,1 C. Wolfe.1

    1OPTN Ad Hoc Disease Transmission Advisory Committee, Richmond, VA; 2United Network for Organ Sharing, Richmond, VA.

    Background: The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including infections (I) & malignancies (M), to assess for donor transmitted…
  • 2015 American Transplant Congress

    Cancer Mortality Among Recipients of Solid Organ Transplant in Ontario

    S. Acuna,1,2,3 K. Fernandes,4 C. Daly,2,3 L. Hicks,3 R. Sutradhar,1,4 S. Kim,1,4 N. Baxter.1,2,3,4

    1Institute of Health Policy, Management and Education, University of Toronto, Toronto, ON, Canada; 2Department of Surgery, St. Michael's Hospital, Toronto, ON, Canada; 3Keenan Research Centre, Li Ka Shing Knowledge Institute, St. Michael's Hospital, Toronto, ON, Canada; 4Institute for Clinical Evaluative Sciences, Toronto, ON, Canada.

    Purpose: Solid organ transplantation recipients (SOTR) have a higher risk of some cancers than the general population, but are also at high risk of mortality…
  • 2015 American Transplant Congress

    Pediatrics & Donor Derived Disease Transmission: The US OPTN Experience

    M. Green,1 S. Taranto,2 S. Covington,2 M. Michaels,1 C. Wolfe,3 D. Kaul.4

    1Pediatrics & Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA; 2OPTN/UNOS, Richmond, VA; 3Medicine, Duke University School of Medicine, Durham, NC; 4Medicine, University of Michigan School of Medicine, Ann Arbor, MI.

    Potential donor derived disease transmission events (PDDTE) are tracked by the OPTN DTAC. Specific evaluation of potential transmissions from pediatric (ped) donors or the impact…
  • 2015 American Transplant Congress

    Kidney Transplantation After Hematopoietic Cell Transplantation in Plasma Cell Dyscrasias

    V. Domínguez-Pimentel,1 F. Fortich-Barrios,1 O. Siverio-Morales,1 E. Martín-Izquierdo,1 A. Jarque-López,1 N. Del Castillo-Rodríguez,1 J. García,1 P. Ríos,2 M. Macía.1

    1Division of Nephrology, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain; 2Division of Hematology, Hospital Nuestra Señora de la Candelaria, Santa Cruz de Tenerife, Spain.

    INTRODUCTION:The plasma cell dyscrasias (PCD) include a number of entities such as multiple myeloma (MM), primary amyloidosis (AL) and Monoclonal immunoglobulin deposition disease (MIDD). Hematopoietic…
  • 2015 American Transplant Congress

    Multicenter Study to Develop a Novel Prediction Index for Hepatocellular Carcinoma (HCC) Recurrence After Liver Transplant (LT)

    N. Mehta,1 J. Heimbach,2 D. Harnois,3 J. Dodge,1 J. Burns,3 D. Lee,3 W. Sanchez,2 J. Roberts,1 F. Yao.1

    1UCSF, San Francisco, CA; 2Mayo Clinic, Rochester, MN; 3Mayo Clinic, Jacksonville, FL.

    Several factors have been associated with a high risk of recurrence of hepatocellular carcinoma (HCC) after liver transplantation (LT), but no reliable risk score has…
  • 2015 American Transplant Congress

    Detecting Bowel Cancer in Pre-Dialysis, Dialysis Patients and Kidney Transplant Recipients – The DETECT Study

    G. Wong, J. Chapman, J. Craig.

    University of Sydney, Sydney, NSW, Australia.

    Background: Colorectal cancer (CRC) is the third most common solid organ cancer in people living with kidney disease, and has a very poor prognosis, with…
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