ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Pre-Transplant Prostate Cancer in Lung Transplant Recipients and Impact on Post-Transplant Morbidity and Mortality.

S. Ajani, M. Valapour, M. Budev.

Respiratory Institute, Cleveland Clinic, Cleveland, OH.

Meeting: 2016 American Transplant Congress

Abstract number: B292

Keywords: Lung transplantation, Malignancy, Outcome

Session Information

Date: Sunday, June 12, 2016

Session Name: Poster Session B: Lung Transplantation Posters

Session Time: 6:00pm-7:00pm

 Presentation Time: 6:00pm-7:00pm

Location: Halls C&D

Related Abstracts
  • Prostate Cancer Characteristics and Outcome in Renal Transplant Recipients: Results from a Contemporary Monocentric Study.
  • Therapeutic Management and Outcome of the Novo Prostate Cancer in Renal Transplant Recipients

Purpose

Assess the impact of pre-transplant prostate cancer on mortality after lung transplant and the incidence of recurrence of prostate cancer after transplant.

Methods

The electronic medical records were reviewed for patients that underwent lung transplant from January 1, 1997 to December 31, 2012 at our center. Individuals were included in this retrospective study if they were male, ≥ 50 years of age at transplant, and undergoing first lung transplant. Collected information included history of prostate cancer, time interval from cancer diagnosis to transplant, recurrence of prostate cancer post-transplant, last follow up date and mortality status as of December 31, 2014. We used the Kaplan-Meier curve and log-rank test to assess mortality difference between individuals with and without a history of prostate cancer.

Results

From January 1, 1997 to December 31, 2012, 1054 transplants were performed and 465 patients were included in the analysis. Thirteen individuals (2.8%) had a history of prostate cancer prior to transplant with median interval from diagnosis of prostate cancer to lung transplant of 43 months (range 6-228). Patients were followed for a median of 24.4 months (range 0.7-64.6) post-transplant and 5 (38.5%) were alive at the end of follow up. No patients had recurrence of prostate cancer. Log-rank test did not demonstrate a statistically significant difference in mortality (p=0.08) in those with and without a history of prostate cancer prior to lung transplant with Kaplan-Meier curve below (Figure 1).

Discussion

We did not find a significant impact of pre-transplant prostate cancer on post-transplant mortality in those who have undergone lung transplant. Due to the low prevalence of prostate cancer in our cohort, we were unable to perform a multivariable analysis to account for confounders. There were no instances of recurrence of prostate cancer after lung transplant, including in the 5 individuals who underwent transplant less than 2 years after prostate cancer diagnosis. Further studies are needed to describe this cohort further.

Figure 1: Kaplan-Meier survival curve for those with and without a history of prostate cancer prior to transplantation.

CITATION INFORMATION: Ajani S, Valapour M, Budev M. Pre-Transplant Prostate Cancer in Lung Transplant Recipients and Impact on Post-Transplant Morbidity and Mortality. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Ajani S, Valapour M, Budev M. Pre-Transplant Prostate Cancer in Lung Transplant Recipients and Impact on Post-Transplant Morbidity and Mortality. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/pre-transplant-prostate-cancer-in-lung-transplant-recipients-and-impact-on-post-transplant-morbidity-and-mortality/. Accessed March 5, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Role of Mitochondria, Metabolism and Inflammation: Pathways Influencing Short Term Outcomes Post-Renal Transplantation
    • Factors Influencing Creatinine Rise Following Donor Nephrectomy

    Visit Our Partner Sites

    American Transplant Congress (ATC)

    Visit the official site for the American Transplant Congress »

    American Journal of Transplantation

    The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

    American Society of Transplantation (AST)

    An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

    American Society of Transplant Surgeons (ASTS)

    The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

    Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

    Privacy Policy

    loading Cancel
    Post was not sent - check your email addresses!
    Email check failed, please try again
    Sorry, your blog cannot share posts by email.
    This site uses cookies: Find out more.