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Articles tagged "Malignancy"

  • 2017 American Transplant Congress

    Donor Derived Transmission Events in 2015-2016: Analysis of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).

    C. Wolfe,1 M. Clark,2 S. Tlusty,2 D. Kaul,1 M. Michaels.1

    1DTAC, Richmond; 2United Network for Organ Sharing, Richmond

    The OPTN DTAC, a multidisciplinary committee, evaluates potential donor derived transmission events (PDDTE), including mostly infections (I) & malignancies (M), to assess for likelihood of…
  • 2017 American Transplant Congress

    10 Years of DTAC Experience with Kaposi's Sarcoma – Not Just Another PTLD!

    M. Nalesnik,1 M. Clark,2 S. Tlusty,2 M. Michaels,1 C. Wolfe.1

    1DTAC, Richmond; 2United Network for Organ Sharing, Richmond

    Background:Kaposi's Sarcoma (KS), a tumor derived from the oncogenic virus human herpesvirus-8 (HHV8) is strongly associated with immunodeficiencies. Classically seen with AIDS, it can also…
  • 2017 American Transplant Congress

    Risk of Primary Central Nervous System Lymphoma in Solid Organ Transplant Recipients.

    E. Engels, P. Mahale, M. Shiels.

    National Cancer Institute, Bethesda, MD

    Background: Risk of primary central nervous system lymphoma (PCNSL) is greatly increased in immunosuppressed HIV-infected people. Case series describe PCNSL in solid organ transplant (SOT)…
  • 2017 American Transplant Congress

    The Effiency and Safety of Chemotherapy for Urothelial Carcinoma in Post-Kidney Transplanted Patients.

    Y. Zhu, J. Lin.

    Urology, Capital Medical University Beijing Friendship Hospital, Beijing, China

    Objective: According to our published data, upper tract urothelial carcinoma (UTUC) is the predominant malignancy among Chinese renal transplanted patients. This is quite different from…
  • 2016 American Transplant Congress

    Age Adapted Immunosuppression for Elderly Kidney Allograft Recipients: Balancing Risks for Cancer versus Rejection.

    F. Jackson-Spence,1 H. Gillott,1 S. Tahir,1 F. Evison,2 J. Nath,3 A. Sharif.3

    1University of Birmingham Medical School, Birmingham, United Kingdom; 2Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

    Introduction Cancer is a growing cause of morbidity and mortality after kidney transplantation, driven by immunosuppression. Age is one of the strongest risk factors for…
  • 2016 American Transplant Congress

    A Decade of Donor-Derived Disease: A Report of the OPTN Ad Hoc Disease Transmission Advisory Committee (DTAC).

    D. Kaul,1 S. Tlusty,2 A. Wilk,2 C. Wolfe.1

    1OPTN Ad Hoc Disease Transmission Advisory Committee, Richmond, VA; 2United Network for Organ Sharing, Richmond, VA.

    Intro: The OPTN DTAC evaluates potential donor derived transmission events (PDDTE), including infections & malignancies, to assess for donor transmitted events.Methods: Reports of unexpected PDDTE…
  • 2016 American Transplant Congress

    Incidence of Post-Transplant Malignancy (PTM) After Pediatric Kidney Transplantation (PKTx).

    O. Serrano,1 A. Bangdiwala,2 D. Vock,2 W. Payne,1 T. Dunn,1 S. Chinnakotla,1 E. Finger,1 R. Kandaswamy,1 T. Pruett,1 A. Matas,1 B. Chavers.3

    1Surgery, Univ. of Minnesota, Minneapolis, MN; 2Biostatistics, Univ. of Minnesota, Minneapolis, MN; 3Pediatrics, Univ. of Minnesota, Minneapolis, MN.

    PURPOSE: Post-transplant immunosuppression is associated with an increase in cancer rates. To date, the long-term incidence of PTM among PKTx recipients has not been well-characterized.METHODOLOGY:…
  • 2016 American Transplant Congress

    The Heterogenous Genomic Landscape of Unresectable Hepatoblastoma Requiring Liver Transplantation: Prognostic Implications.

    M. Ningappa, B. Higgs, S. Ranganathan, C. Ashokkumar, R. Sindhi.

    Surgery, Children's Hospital of Pittsburgh of UPMC and University of Pittsburgh, Pittsburgh, PA.

    Background: Hepatoblastoma, the most common pediatric liver malignancy, is cured by chemotherapy and surgical resection. Locally invasive/multifocal tumors require liver transplantation (LTx). A unique tumor…
  • 2016 American Transplant Congress

    Stratifying Skin Versus Non-Skin Cancer Risk Post-Kidney Transplantation According to Patient Characteristics.

    F. Jackson-Spence,1 H. Gillott,1 S. Tahir,1 F. Evison,2 J. Nath,3 A. Sharif.3

    1University of Birmingham Medical School, Birmingham, United Kingdom; 2Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom; 3Queen Elizabeth Hospital Birmingham, Birmingham, United Kingdom.

    Introduction Cancer is a significant cause of morbidity and mortality after kidney transplantation but risk differs e.g. non-melanoma skin cancers have a better prognosis compared…
  • 2016 American Transplant Congress

    Prostate Cancer Characteristics and Outcome in Renal Transplant Recipients: Results from a Contemporary Monocentric Study.

    C. Pettenati,1 A.-S. Jannot,2 V. Verkarre,3 S. Hurel,1 H. Kreis,4 M. Housset,5 C. Legendre,4 A. Méjean,1 M.-O. Timsit.1

    1Department of Urology and Transplant surgery, Hôpital Européen Georges Pompidou, AP-HP, Université Paris Descartes, Paris, France; 2Department of Statistics, Computing and Public Health, Hôpital Européen Georges Pompidou, AP-HP, Université Paris Descartes, Paris, France; 3Department of Pathology, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France; 4Department of Nephrology and Transplantation, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France; 5Department of Onco-Radiotherapy, Hôpital Necker, AP-HP, Université Paris Descartes, Paris, France.

    Objective To analyze prostate cancer characteristics in a contemporary monocentric renal transplant recipients (RTR) population and to compare oncological outcome after radical prostatectomy (RP) with…
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