ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung"

  • 2020 American Transplant Congress

    Impact of Ozone Exposure of Lung Donors and Recipients on All-Cause Mortality after Lung Transplant

    T. Egan1, S. Arunachalam2, C. Chang2, P. Strassle1

    1Surgery, UNC at Chapel Hill, Chapel Hill, NC, 2Institute of the Environment, UNC at Chapel Hill, Chapel Hill, NC

    *Purpose: A Belgian study found proximity to a motorway increased risk of bronchiolitis obliterans syndrome after lung transplant (LT). Using zip codes as a surrogate…
  • 2020 American Transplant Congress

    First Report of Successful CD38-Antagonist Daratumumab Augmented Carfilzomib-Based Treatment of Refractory Definite AMR of the Lung Allograft

    M. N. Kildea1, C. R. Ensor1, J. Kim1, L. Bogar1, D. Colella1, R. D. Davis1, M. Marschner1, A. Zeevi2, N. Soe1, C. Gries1

    1AdventHealth, Orlando, FL, 2University of Pittsburgh, Pittsburgh, PA

    *Purpose: Antibody-mediated rejection (AMR) after lung transplant (LT) is associated with early progressive chronic lung allograft dysfunction (CLAD) and death. Therapeutic regimens remain poorly evaluated.…
  • 2020 American Transplant Congress

    Effectiveness of Routine Screening for Mycoplasma Hominis and Ureaplasma spp. in Lung Transplant Recipients

    P. Vijayvargiya, Z. Esquer Garrigos, C. C. Kennedy, R. C. Daly, M. E. Wylam, E. Beam

    Mayo Clinic, Rochester, MN

    *Purpose: In lung transplant recipients Mycoplasma hominis and Ureaplasma spp. may cause localized or disseminated infection and fatal hyperammonemia syndrome (HS). Optimal prevention strategies are…
  • 2020 American Transplant Congress

    Impact of Pretransplant Malignancy on Heart and Lung Transplant Recipients

    W. Kang1, C. T. Sparrow2, M. Kim1, M. Rachid3, S. M. Soriano3

    1Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, 2Department of Cardiology, University of Illinois College of Medicine at Peoria, Peoria, IL, 3Department of Pulmonology, University of Illinois College of Medicine at Peoria, Peoria, IL

    *Purpose: The purpose of this study is to investigate pre-transplant malignancy (PTM) as a risk factor for worsened post-transplant prognosis in heart or lung transplant…
  • 2020 American Transplant Congress

    Measuring and Monitoring Equity in Access to Deceased Donor Lung Transplants among Lung Registrations

    R. R. Goff1, E. D. Lease2, S. Sweet3, A. Robinson1, D. Stewart1

    1Research, United Network for Organ Sharing, Richmond, VA, 2University of Washington, Seattle, WA, 3St. Louis Children's Hospital, St. Louis, MO

    *Purpose: In 2018, the Organ Procurement and Transplantation Network (OPTN) published a methodology to measure equity in access to deceased donor kidney transplantation that has…
  • 2020 American Transplant Congress

    Improved Platelet Sequestration with Humanization of Von Willebrand Factor in Pig Xenogeneic Lung Perfusion Model

    M. R. Connolly1, L. Burdorf1, Z. Abady1, S. Sendil2, E. Redding2, B. Cerel1, S. Pratts1, C. Phelps3, W. Eyestone3, D. Ayares3, A. Azimzadeh1, R. N. Pierson III1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2University of Maryland, Baltimore, Baltimore, MD, 3Revivicor, Blacksburg, VA

    *Purpose: Von Willebrand factor (vWF) is an important element of hemostasis and when activated, mediates platelet adhesion and promotes platelet aggregation under shear stress conditions.…
  • 2020 American Transplant Congress

    Effects of Subnormothermic Ex Vivo Lung Perfusion on Inflammatory Injury in a Murine Lung Transplant Model

    J. N. Gloria1, S. J. Kesseli2, J. Yerxa2, M. Zhang2, M. Zhu2, W. Parker2, R. P. Davis2, A. S. Barbas2, M. G. Hartwig3

    1Duke University School of Medicine, Durham, NC, 2Department of Surgery, Duke University Medical Center, Durham, NC, 3Department of Thoracic Surgery, Duke University Medical Center, Durham, NC

    *Purpose: Ex vivo lung perfusion (EVLP) has emerged as a technique that safely preserve lungs prior to transplantation. Recent evidence demonstrates increased levels of inflammatory…
  • 2020 American Transplant Congress

    Comparative Analysis of Risk Factors and Outcomes in Kidney Transplant Recipients with Lung Cancer and Those with No Malignancy: UNOS Data Set

    H. Patel1, V. Nissaisorakarn2, E. Sula Karrecci1, N. Agrawal1, F. Cardarelli1

    1Transplant Nephrology, Beth Israel Deaconess Medical Center, Boston, MA, 2Department of Internal Medicine, Metrowest Medical Center, Boston, MA

    *Purpose: Transplant recipients are at increased risk for malignancy. Patients who develop cancer after transplant have worse outcomes, especially those with lung cancer. Transplant-related risk…
  • 2020 American Transplant Congress

    Evaluation of SUBA-Itraconazole Use in Lung Transplant Recipients

    J. G. Youssef1, C. Ahmed1, B. J. Pierce2, C. Pham2, F. Ye1, K. Tatum1, S. Yau1, A. Goodarzi1, H. J. Huang1

    1Department of Medicine, Houston Methodist Hospital, Houston, TX, 2Department of Pharmacy, Houston Methodist Hospital, Houston, TX

    *Purpose: Itraconazole (IT) is commonly used after lung transplant for fungal prophylaxis, particularly in those with a history of skin cancer, concern for Histoplasmosis infection,…
  • 2020 American Transplant Congress

    Alternate Triazole Therapy for Breakthrough Invasive Fungal Disease in Lung Transplant Recipients on Triazole Prophylaxis

    A. Abbas, H. Hassouna, F. Marco Canosa, K. D. Brizendine

    Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Invasive fungal diseases (IFD) are a leading cause of infection related morbidity and mortality in lung transplant (LT) recipients. Data regarding outcomes of breakthrough…
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