ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung"

  • 2020 American Transplant Congress

    The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion

    K. Noda1, B. J. Philips1, M. Velayutham2, T. Harano1, P. Reck dos Santos1, S. Shiva2, P. G. Sanchez1

    1Department of Cardiothoracic Surgery, University of Pittsburgh, Pittsburgh, PA, 2Department of Medicine, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…
  • 2020 American Transplant Congress

    Statin Use May Be Associated with Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients

    A. Perez Cortes Villalobos, F. Foroutan, S. Davoudi, T. Martinu, J. Tikkanen, L. Singer, S. Keshavjee, S. Husain

    University Health Network, Toronto, ON, Canada

    *Purpose: Statins are competitive inhibitors of HMG-CoA reductase, that catalyses the conversion of HMG-CoA to mevalonate, which is involved in the synthesis of cholesterol in…
  • 2020 American Transplant Congress

    Ambient Air Pollution and Waitlist Mortality among Lung Transplant Candidates

    Y. Feng1, M. R. Jones2, N. Chu1, D. Segev1, M. McAdams-DeMarco1

    1Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD, 2Department Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD

    *Purpose: Previous studies suggested that air pollution is associate with higher risk of respiratory diseases and accelerated decline in lung function among general population. However,…
  • 2020 American Transplant Congress

    Case Series of Belatacept for Calcineurin Inhibitor Sparing after Lung Transplantation

    H. Patel, C. R. Ensor, R. D. Davis, L. Bogar, D. Colella, M. Kildea, J. Kim, A. Satterthwaite, D. Ventura, C. Gries

    AdventHealth, Orlando, FL

    *Purpose: Belatacept is a recombinant soluble fusion protein which selectively blocks T-cell co-stimulation. It received initial FDA approval for prophylaxis of organ rejection in Epstein-Barr…
  • 2020 American Transplant Congress

    Impact of Ozone Exposure of Lung Donors and Recipients on All-Cause Mortality after Lung Transplant

    T. Egan1, S. Arunachalam2, C. Chang2, P. Strassle1

    1Surgery, UNC at Chapel Hill, Chapel Hill, NC, 2Institute of the Environment, UNC at Chapel Hill, Chapel Hill, NC

    *Purpose: A Belgian study found proximity to a motorway increased risk of bronchiolitis obliterans syndrome after lung transplant (LT). Using zip codes as a surrogate…
  • 2020 American Transplant Congress

    First Report of Successful CD38-Antagonist Daratumumab Augmented Carfilzomib-Based Treatment of Refractory Definite AMR of the Lung Allograft

    M. N. Kildea1, C. R. Ensor1, J. Kim1, L. Bogar1, D. Colella1, R. D. Davis1, M. Marschner1, A. Zeevi2, N. Soe1, C. Gries1

    1AdventHealth, Orlando, FL, 2University of Pittsburgh, Pittsburgh, PA

    *Purpose: Antibody-mediated rejection (AMR) after lung transplant (LT) is associated with early progressive chronic lung allograft dysfunction (CLAD) and death. Therapeutic regimens remain poorly evaluated.…
  • 2020 American Transplant Congress

    Effectiveness of Routine Screening for Mycoplasma Hominis and Ureaplasma spp. in Lung Transplant Recipients

    P. Vijayvargiya, Z. Esquer Garrigos, C. C. Kennedy, R. C. Daly, M. E. Wylam, E. Beam

    Mayo Clinic, Rochester, MN

    *Purpose: In lung transplant recipients Mycoplasma hominis and Ureaplasma spp. may cause localized or disseminated infection and fatal hyperammonemia syndrome (HS). Optimal prevention strategies are…
  • 2020 American Transplant Congress

    Impact of Pretransplant Malignancy on Heart and Lung Transplant Recipients

    W. Kang1, C. T. Sparrow2, M. Kim1, M. Rachid3, S. M. Soriano3

    1Internal Medicine, University of Illinois College of Medicine at Peoria, Peoria, IL, 2Department of Cardiology, University of Illinois College of Medicine at Peoria, Peoria, IL, 3Department of Pulmonology, University of Illinois College of Medicine at Peoria, Peoria, IL

    *Purpose: The purpose of this study is to investigate pre-transplant malignancy (PTM) as a risk factor for worsened post-transplant prognosis in heart or lung transplant…
  • 2020 American Transplant Congress

    Measuring and Monitoring Equity in Access to Deceased Donor Lung Transplants among Lung Registrations

    R. R. Goff1, E. D. Lease2, S. Sweet3, A. Robinson1, D. Stewart1

    1Research, United Network for Organ Sharing, Richmond, VA, 2University of Washington, Seattle, WA, 3St. Louis Children's Hospital, St. Louis, MO

    *Purpose: In 2018, the Organ Procurement and Transplantation Network (OPTN) published a methodology to measure equity in access to deceased donor kidney transplantation that has…
  • 2020 American Transplant Congress

    Improved Platelet Sequestration with Humanization of Von Willebrand Factor in Pig Xenogeneic Lung Perfusion Model

    M. R. Connolly1, L. Burdorf1, Z. Abady1, S. Sendil2, E. Redding2, B. Cerel1, S. Pratts1, C. Phelps3, W. Eyestone3, D. Ayares3, A. Azimzadeh1, R. N. Pierson III1

    1Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA, 2University of Maryland, Baltimore, Baltimore, MD, 3Revivicor, Blacksburg, VA

    *Purpose: Von Willebrand factor (vWF) is an important element of hemostasis and when activated, mediates platelet adhesion and promotes platelet aggregation under shear stress conditions.…
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