2020 American Transplant Congress
Impact of the 2015 LAS Revisions on Lung Candidates with Pulmonary Vascular Disease
1UNOS, Richmond, VA, 2University of Michigan, Ann Arbor, MI
*Purpose: On February 19, 2015 a major revision to the Lung Allocation Score (LAS) was implemented with the goal of more accurately reflecting waitlist urgency…2020 American Transplant Congress
Is Total Ischemic Time a Measure of OPTN Efficiency? Monitoring the Impact of Lung Allocation Policy on Ischemic Time
*Purpose: There is concern that the shift to circle based organ allocation policy may increase coordination costs. Within both public comment and the peer reviewed…2020 American Transplant Congress
Monitoring the Removal of Donation Service Area from Lung Allocation
*Purpose: In 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor service area (DSA) with a 250…2020 American Transplant Congress
Green Channel of Human Organ Transport (GCHOT) Improved the Utilization Rate of Chinese Citizens’ Donated Lungs: A Single-Center Data Analysis
Wuxi Lung Transplant Center, Wuxi, China
*Purpose: Lung transplantation in China has been developing for over forty years. Wuxi lung transplant center has the largest lung transplant (LT) volume nationwide. It…2020 American Transplant Congress
The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion
*Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…2020 American Transplant Congress
Statin Use May Be Associated with Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients
University Health Network, Toronto, ON, Canada
*Purpose: Statins are competitive inhibitors of HMG-CoA reductase, that catalyses the conversion of HMG-CoA to mevalonate, which is involved in the synthesis of cholesterol in…2020 American Transplant Congress
Ambient Air Pollution and Waitlist Mortality among Lung Transplant Candidates
*Purpose: Previous studies suggested that air pollution is associate with higher risk of respiratory diseases and accelerated decline in lung function among general population. However,…2020 American Transplant Congress
Case Series of Belatacept for Calcineurin Inhibitor Sparing after Lung Transplantation
*Purpose: Belatacept is a recombinant soluble fusion protein which selectively blocks T-cell co-stimulation. It received initial FDA approval for prophylaxis of organ rejection in Epstein-Barr…2020 American Transplant Congress
Impact of Ozone Exposure of Lung Donors and Recipients on All-Cause Mortality after Lung Transplant
*Purpose: A Belgian study found proximity to a motorway increased risk of bronchiolitis obliterans syndrome after lung transplant (LT). Using zip codes as a surrogate…2020 American Transplant Congress
First Report of Successful CD38-Antagonist Daratumumab Augmented Carfilzomib-Based Treatment of Refractory Definite AMR of the Lung Allograft
1AdventHealth, Orlando, FL, 2University of Pittsburgh, Pittsburgh, PA
*Purpose: Antibody-mediated rejection (AMR) after lung transplant (LT) is associated with early progressive chronic lung allograft dysfunction (CLAD) and death. Therapeutic regimens remain poorly evaluated.…
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