2021 American Transplant Congress
Evaluation of Fungal Prophylaxis Post-Lung Transplantation
1Temple University Hospital, Philadelphia, PA, 2Temple School of Pharmacy, Philadelphia, PA
*Purpose: Fungal infections are responsible for approximately 15-35% of all infections in lung transplant recipients; 80% of which are due to aspergillus or candida. At…2021 American Transplant Congress
Impact of Positive Donor Cultures on Postoperative Lung Transplantation Infectious Outcomes
Houston Methodist Hospital, Houston, TX
*Purpose: Transmission risk of microbes present in donor lungs at time of donation to lung transplant recipients (LTR) is unclear. Infection is the second highest…2021 American Transplant Congress
Donor-Derived Tuberculosis in Lung Transplant Recipients, a Single Center Experience
University of Alberta, Edmonton, AB, Canada
*Purpose: Donor-derived (DD) tuberculosis (TB) in solid-organ transplantation (SOT) is rare with the largest review to date identifying only 25 cases of proven or probable…2021 American Transplant Congress
Evaluation of Meningococcal Vaccine Response Among Solid Organ Transplant Recipients Receiving Eculizumab
*Purpose: Patients receiving eculizumab are at a 1,000-2,000-fold increased risk of invasive meningococcal infections. Therefore, the Advisory Committee for Immunization Practices recommends that these patients…2021 American Transplant Congress
Composition of Ex Vivo Lung Perfusion Solutions and Kinetics Define Differential Cytokine and Chemokine Secretion in a Porcine Cardiac Arrest Model of Lung Preservation
*Purpose: Ex vivo lung perfusion is an innovative technique to evaluate marginal lung organs especially after DCD. Normothermic continuous perfusion should reduce ischemic damage and…2021 American Transplant Congress
Imaging Flow Cytometry Reveals That Platelet-Sized Erythrocyte Fragments are Formed During Pig Organ Perfusion with Human Blood
*Purpose: Severe thrombocytopenia frequently occurs after xenotransplantation of porcine cells or organs, and when pig organs are perfused with human blood. We developed a flow…2021 American Transplant Congress
Aligning Pediatric Waiting List and Post-Transplant Outcomes with the Adult Lung Allocation Score
*Purpose: Lung allocation is moving toward a continuous distribution framework (CDF), with components for waitlist (WL) urgency and post-transplant (PT) survival, as computed in LAS.…2021 American Transplant Congress
Beneficial Effects of Argon Inhalation on Reducing Lung Ischemia-reperfusion Injury in Miniature Swine
*Purpose: Noble gases, such as xenon and argon (Ar), are chemically inert but have shown to have cytoprotective effect. In contrast to xenon, Ar is…2021 American Transplant Congress
Nanoparticle Mediated Drug Delivery for Lung Transplantation
*Purpose: Severe primary graft dysfunction (PGD) affects 30% of lung transplant patients. Pulmonary alveolar macrophages play a significant role in lung PGD, but systemic immunotherapy…2021 American Transplant Congress
Sensitized Lung Candidates Experience Reduced Access to Donor Organs
1UNOS, Richmond, VA, 2UNOS, Richmnd, VA
*Purpose: Most studies of sensitization in transplant candidates have focused on kidney candidates, and unacceptable antigens (UAs) for non-kidney candidates are believed to be underreported.…
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