2021 American Transplant Congress
Nanoparticle Mediated Drug Delivery for Lung Transplantation
*Purpose: Severe primary graft dysfunction (PGD) affects 30% of lung transplant patients. Pulmonary alveolar macrophages play a significant role in lung PGD, but systemic immunotherapy…2021 American Transplant Congress
Beneficial Effects of Argon Inhalation on Reducing Lung Ischemia-reperfusion Injury in Miniature Swine
*Purpose: Noble gases, such as xenon and argon (Ar), are chemically inert but have shown to have cytoprotective effect. In contrast to xenon, Ar is…2021 American Transplant Congress
Aligning Pediatric Waiting List and Post-Transplant Outcomes with the Adult Lung Allocation Score
*Purpose: Lung allocation is moving toward a continuous distribution framework (CDF), with components for waitlist (WL) urgency and post-transplant (PT) survival, as computed in LAS.…2021 American Transplant Congress
Imaging Flow Cytometry Reveals That Platelet-Sized Erythrocyte Fragments are Formed During Pig Organ Perfusion with Human Blood
*Purpose: Severe thrombocytopenia frequently occurs after xenotransplantation of porcine cells or organs, and when pig organs are perfused with human blood. We developed a flow…2020 American Transplant Congress
Monitoring the Removal of Donation Service Area from Lung Allocation
*Purpose: In 2017 the Organ Procurement and Transplantation Network (OPTN) altered US lung allocation policy by replacing the donor service area (DSA) with a 250…2020 American Transplant Congress
Green Channel of Human Organ Transport (GCHOT) Improved the Utilization Rate of Chinese Citizens’ Donated Lungs: A Single-Center Data Analysis
Wuxi Lung Transplant Center, Wuxi, China
*Purpose: Lung transplantation in China has been developing for over forty years. Wuxi lung transplant center has the largest lung transplant (LT) volume nationwide. It…2020 American Transplant Congress
The Negative Impact of Inherent Oxidative Stress in Marginal Lungs on Ex Vivo Lung Perfusion
*Purpose: Identifying good quality grafts within the donor pool, ex vivo lung perfusion (EVLP) opens another window to evaluate grafts initially declined with marginal quality…2020 American Transplant Congress
Statin Use May Be Associated with Lower Risk of Invasive Aspergillosis in Lung Transplant Recipients
University Health Network, Toronto, ON, Canada
*Purpose: Statins are competitive inhibitors of HMG-CoA reductase, that catalyses the conversion of HMG-CoA to mevalonate, which is involved in the synthesis of cholesterol in…2020 American Transplant Congress
Ambient Air Pollution and Waitlist Mortality among Lung Transplant Candidates
*Purpose: Previous studies suggested that air pollution is associate with higher risk of respiratory diseases and accelerated decline in lung function among general population. However,…2020 American Transplant Congress
Case Series of Belatacept for Calcineurin Inhibitor Sparing after Lung Transplantation
*Purpose: Belatacept is a recombinant soluble fusion protein which selectively blocks T-cell co-stimulation. It received initial FDA approval for prophylaxis of organ rejection in Epstein-Barr…
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