2021 American Transplant Congress
Imaging Flow Cytometry Reveals That Platelet-Sized Erythrocyte Fragments are Formed During Pig Organ Perfusion with Human Blood
*Purpose: Severe thrombocytopenia frequently occurs after xenotransplantation of porcine cells or organs, and when pig organs are perfused with human blood. We developed a flow…2021 American Transplant Congress
Composition of Ex Vivo Lung Perfusion Solutions and Kinetics Define Differential Cytokine and Chemokine Secretion in a Porcine Cardiac Arrest Model of Lung Preservation
*Purpose: Ex vivo lung perfusion is an innovative technique to evaluate marginal lung organs especially after DCD. Normothermic continuous perfusion should reduce ischemic damage and…2021 American Transplant Congress
Evaluation of Meningococcal Vaccine Response Among Solid Organ Transplant Recipients Receiving Eculizumab
*Purpose: Patients receiving eculizumab are at a 1,000-2,000-fold increased risk of invasive meningococcal infections. Therefore, the Advisory Committee for Immunization Practices recommends that these patients…2021 American Transplant Congress
Donor-Derived Tuberculosis in Lung Transplant Recipients, a Single Center Experience
University of Alberta, Edmonton, AB, Canada
*Purpose: Donor-derived (DD) tuberculosis (TB) in solid-organ transplantation (SOT) is rare with the largest review to date identifying only 25 cases of proven or probable…2021 American Transplant Congress
Impact of Positive Donor Cultures on Postoperative Lung Transplantation Infectious Outcomes
Houston Methodist Hospital, Houston, TX
*Purpose: Transmission risk of microbes present in donor lungs at time of donation to lung transplant recipients (LTR) is unclear. Infection is the second highest…2021 American Transplant Congress
Evaluation of Fungal Prophylaxis Post-Lung Transplantation
1Temple University Hospital, Philadelphia, PA, 2Temple School of Pharmacy, Philadelphia, PA
*Purpose: Fungal infections are responsible for approximately 15-35% of all infections in lung transplant recipients; 80% of which are due to aspergillus or candida. At…2021 American Transplant Congress
Tacrolimus Dose Requirements in Lung Transplant Recipients on Systemic Azole Antifungals: The Influence of Race and Transplant Indication
*Purpose: CYP3A5 polymorphisms, drug interactions, and alterations in gastric absorption impact tacrolimus metabolism. This is important for those at higher risk of expressing these factors,…2021 American Transplant Congress
Combined Liver and Lung Transplantation with Extended Normothermic Liver Preservation Using Transmedics Organ Care System (OCS)TM Liver: A Single Center Experience
*Purpose: Combined liver-lung transplantation (CLLT) is indicated in patients who cannot survive single-organ transplantation alone. Ex-situ normothermic machine perfusion (NMP) has been used to increase…2021 American Transplant Congress
A Patient-Centered Perspective on Progress in Transplantation
*Purpose: This study aimed to provide a patient-centered perspective on change in transplantation outcomes through analysis of intent-to-treat survival, which accounted for donor shortages by…2021 American Transplant Congress
Evaluate the Effect of Cresemba (isavuconazonium Sulfate) Capsule and Noxafil (posaconazole) Delayed Release Tablets on Tacrolimus Dose to Concentration (D/C) Ratios in Lung Transplant Recipients
*Purpose: Evaluate the effect of Cresemba (isavuconazonium sulfate) capsule and Noxafil (posaconazole) delayed release tablet on tacrolimus dose to concentration (D/C) ratio in lung transplant.*Methods:…
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