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Articles tagged "Lung"

  • 2022 American Transplant Congress

    Do CMS Oversight and the Systems Improvement Agreement Really Change Institutional Behavior?

    C. Hoopes

    University of Alabama Birmingham, Birmingham, AL

    *Purpose: A Systems Improvement Agreement (SIA) is a voluntary and binding legal agreement between CMS and a Medicare certified hospital designed to address Condition level…
  • 2022 American Transplant Congress

    Utility of Bronchoalveolar Lavage Cytology for Detection of Malignancy or Infection in Lung Transplant Recipients

    G. Cerro Chiang1, R. Rampolla2

    1Department of Medicine, Cedars Sinai Medical Center, Los Angeles, CA, 2Department o Medicine, Cedars Sinai Medical Center, Los Angeles, CA

    *Purpose: The role of cytologic evaluation in the diagnosis of acute allograft dysfunction has been described. Specific changes in cell count of bronchoalveolar lavage during…
  • 2022 American Transplant Congress

    Direct Central Ambulatory Venoarterial Extracorporeal Membrane Oxygenation and Double Lung Transplantation without Graft Reduction with Extreme Mediastinal Shift

    A. Gorton1, S. Keshavamurthy2

    1Cardiothoracic Surgery, University of Kentucky, Lexington, KY, 2University of Kentucky, Lexington, KY

    *Purpose: Double Lung transplantation in the presence of extreme mediastinal shift can be technically challenging due to donor sizing and recipient factors.*Methods: We present the…
  • 2022 American Transplant Congress

    Evaluation of Crushed Posaconazole Delayed Release Tablets in Lung Transplant Recipients

    R. Gordon1, K. Dewey1, R. Jariwala1, B. Yen1, J. Kukreja2, S. Hays2, J. Singer2, R. Florez1

    1Department of Clinical Pharmacy, University of California, San Francisco, San Francisco, CA, 2University of California, San Francisco, San Francisco, CA

    *Purpose: We hypothesized that crushed posaconazole delayed release (POSA DR) tablets can reach therapeutic levels in lung transplant recipients who are at risk for invasive…
  • 2022 American Transplant Congress

    Donor-Derived Cell-Free DNA Across the Spectrum of Solid Organ Transplantation

    S. R. Potter1, J. Miles2, K. Qu2, R. Woodward2, S. Dholakia2

    1Baylor Scott & White Health, Temple, TX, 2CareDx, Inc, Brisbane, CA

    *Purpose: Donor-derived cell-free DNA (dd-cfDNA) is a robust and clinically useful analyte initially validated for kidney allograft surveillance. Emerging data support the utility of dd-cfDNA…
  • 2022 American Transplant Congress

    Dynamic Changes and Roles of Specialized Pro-resolving Lipid Meditators in the Initiation and Resolution Process of Lung Ischemia-Reperfusion Injury in Rats

    H. Oda1, S. Tanaka1, M. Shinohara2, Y. Morimura1, Y. Yokoyama1, H. Kayawake1, Y. Yamada1, A. Ohsumi1, D. Nakajima1, H. Date1

    1Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto City, Japan, 2The Integrated Center for Mass Spectrometry, Kobe University Graduate School of Medicine, Kobe City, Japan

    *Purpose: Lung ischemia-reperfusion injury (IRI) is one of the significant complications after lung transplantation, which is a form of acute lung injury by robust inflammation.…
  • 2022 American Transplant Congress

    A Model of Idiopathic Pneumonia Syndrome in Rhesus Macaques

    R. S. Bermea1, K. Ingersoll2, L. P. Hariri3, M. Warren2, L. Kean2, V. Tkachev2

    1Pulmonary & Critical Care Medicine, Massachusetts General Hospital, Boston, MA, 2Hematology/Oncology, Boston Children's Hospital, Boston, MA, 3Pathology, Massachusetts General Hospital, Boston, MA

    *Purpose: To create a model of idiopathic pneumonia syndrome (IPS), a deadly complication of hematopoietic stem cell transplantation (HSCT) in Rhesus macaques (RM).*Methods: RM were…
  • 2021 American Transplant Congress

    Renal Preservation with Belatacept-Based versus Everolimus-Based Immunosuppression in Lung Transplant Recipients

    E. Sartain1, K. Schoeppler1, B. Crowther1, J. Smith2, A. Gray2

    1University of Colorado Skaggs School of Pharmacy and Pharmaceutical Sciences, Aurora, CO, 2Department of Medicine, Division of Pulmonary Sciences and Critical Care, University of Colorado, Denver, CO

    *Purpose: Renal dysfunction is one of the most common long-term complications among lung transplant recipients (LTRs). Calcineurin-inhibitor (CNI) nephrotoxicity is a recognized contributor to renal…
  • 2021 American Transplant Congress

    Elexacaftor/ivacaftor/tezacaftor in Lung Transplant Recipients: A Case Series

    L. M. Potter1, B. Vargas2, S. M. Rotolo1, C. McEwen1, K. Tsui1

    1University of Chicago Medicine, Chicago, IL, 2Roosevelt University, Chicago, IL

    *Purpose: Little data is published describing the safety or efficacy of elexacaftor/ivacaftor/tezacaftor in lung transplant recipients. Even though it is not expected to offer pulmonary…
  • 2021 American Transplant Congress

    Impact Analysis of Virtual Transplant Ambulatory Pharmacist During Covid-19

    L. Park, G. Waldman, J. Kim, C. Rogers, J. Clark

    Massachusetts General Hospital, Boston, MA

    *Purpose: During the COVID-19 pandemic, transplant centers were challenged to meet the demand for new telemedicine strategies. High-risk immunocompromised patients, such as lung transplant recipients…
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