Articles tagged "Lung transplantation"

2022 American Transplant Congress
Temporal Trends in Utilization, Discard, and Outcomes for Extended Criteria Donor Lungs
A. Hallett¹, L. Zeiser¹, W. Lightle², J. Ruck¹, J. Alejo¹, A. Massie¹, D. Segev¹
¹Johns Hopkins, Baltimore, MD, ²Baylor, Houston, TX
*Purpose: Extended criteria donor lungs (ECDL) are defined as those failing to meet ≥1 standard donor criteria (P/F > 300, age < 55, smoking <…
2022 American Transplant Congress
Effect of Micafungin Bridging on Prevention of Invasive Candidiasis Post Lung Transplantation
C. Baladad¹, M. Converse¹, K. DeSear¹, S. Karimi¹, E. Rubido¹, G. El Helou², T. Pasley¹
¹Pharmacy, University of Florida Health, Shands, Gainesville, FL, ²Infectious Diseases, University of Florida Health, Shands, Gainesville, FL
*Purpose: This study aims to determine the effect of micafungin, added as a bridging agent to azole antifungal prophylaxis, in lung transplantation patients with positive…
2022 American Transplant Congress
Natural Killer Cell NKG2D Receptor Mediates Airway Cell Hypoxic Injury Through Recognition of Stress Molecules
T. Tsao¹, E. Aminian¹, A. Shemesh¹, L. Tran¹, P. Wang¹, F. Deiter¹, J. R. Greenland², D. R. Calabrese¹
¹University of California, San Francisco, San Francisco, CA, ²Medicine, University of California, San Francisco, CA
*Purpose: Primary graft dysfunction (PGD), the clinical syndrome of pulmonary hypoxia and reperfusion, occurs afer 1/3 of all lung transplants, and accounts for excess mortality.…
2022 American Transplant Congress
Lung Allograft-Resident Eosinophils Maintain Long-Term Graft Integrity by Restraining Humoral Alloimmunity
Z. Mei¹, Y. Guo¹, D. Li¹, M. Khalil¹, A. Banerjee¹, A. Gelman², D. Kreisel², A. Krupnick³
¹Department of Surgery, University of Maryland, Baltimore, Baltimore, MD, ²Washington University in St. Louis, St. Louis, MO, ³Department of Surgery, University of Maryland, Baltimore, baltimore, MD
*Purpose: The finding that eosinophils facilitate immunosuppression-mediated acceptance of murine lung allograft by downregulating alloreactive CD8+ T cells has been recently described by our group.…
2022 American Transplant Congress
Oseltamivir for the Prevention of Influenza Infection in Lung Transplant Recipients at an Academic Medical Center
D. Majmundar, A. Mishkin, J. Burnell, C. Ruggia-Check, J. Au
Temple University Hospital, Philadelphia, PA
*Purpose: Influenza is commonly considered a community acquired infection, but in transplant recipients, nosocomial transmission is frequently encountered. The lung transplant program at Temple University…
2022 American Transplant Congress
The Unique Course of dd-cfDNA After Lung Transplant
D. Levine¹, C. Giner¹, C. Pham², R. Woodward³, A. Roux⁴
¹University of Texas Health System San Antonio, San Antonio, TX, ²CareDX, South San Francisco, CA, ³CareDx, South San Francisco, CA, ⁴Pneumology, Adult CF Center and Lung Transplantation Department, Foch Hospital, Suresnes, France
*Purpose: The time necessary for dd-cfDNA to reach baseline levels following transplantation has been reported in kidney, heart, and liver as 14-21 days. We explored…
2022 American Transplant Congress
Long Term Longitudinal TTV Measurements in Lung Transplant Recipients
E. Gore¹, C. Rondaan¹, E. A. Verschuuren², L. Gard¹, H. G. Niesters¹, C. van Leer-Buter¹
¹Department of Medical Microbiology and Infection Prevention, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands, ²Department of Pulmonary Diseases and Tuberculosis, University of Groningen, University Medical Centre Groningen, Groningen, Netherlands
*Purpose: To investigate how levels of Torque Teno Virus (TTV), a virus which has been proposed as a marker for immunosuppression change over a period…
2022 American Transplant Congress
Dynamic Changes and Roles of Specialized Pro-resolving Lipid Meditators in the Initiation and Resolution Process of Lung Ischemia-Reperfusion Injury in Rats
H. Oda¹, S. Tanaka¹, M. Shinohara², Y. Morimura¹, Y. Yokoyama¹, H. Kayawake¹, Y. Yamada¹, A. Ohsumi¹, D. Nakajima¹, H. Date¹
¹Department of Thoracic Surgery, Kyoto University Graduate School of Medicine, Kyoto City, Japan, ²The Integrated Center for Mass Spectrometry, Kobe University Graduate School of Medicine, Kobe City, Japan
*Purpose: Lung ischemia-reperfusion injury (IRI) is one of the significant complications after lung transplantation, which is a form of acute lung injury by robust inflammation.…
2022 American Transplant Congress
18 Month Review of Liver Acuity Circles Allocation
J. Foutz¹, S. Noreen¹, M. Cafarella¹, A. Wilk¹, J. Trotter², S. Biggins³, J. Pomposelli⁴
¹United Network for Organ Sharing, Richmond, VA, ²Baylor University Medical Center, Dallas, TX, ³University of Washington, Seattle, WA, ⁴University of Colorado, Aurora, CO
*Purpose: Acuity circles (AC) allocation was implemented on 2/4/2020 with a goal of removing DSA and region from liver allocation and broadening the distribution of…
2022 American Transplant Congress
Evaluation of Voriconazole Dosing for Preventing Aspergillus in Lung Transplant Recipients
A. Chaplain¹, B. J. Pierce¹, C. Pham¹, A. Hutchins¹, W. L. Musick¹, D. T. Nguyen², E. A. Graviss², S. W. Yau³, J. G. Youssef³, A. Goodarzi³, H. J. Huang³
¹Pharmacy, Houston Methodist Hospital, Houston, TX, ²Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, ³Medicine, Houston Methodist Hospital, Houston, TX
*Purpose: We sought to evaluate the efficacy of voriconazole (VCZ) 200 mg twice a day (BID) for 3 months post lung transplant (LT) in preventing…

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