ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2015 American Transplant Congress

    The Impact of Alemtuzumab and Basiliximab Induction On Patient and Graft Survival in Single Lung Transplant Recipients

    Y. Furuya,1 S. Jayarajan,2 S. Taghavi,2 V. Ambur,2 F. Cordova,3 N. Patel,3 Y. Toyoda.4

    1Internal Medicine, Temple University Hospital, Philadelphia, PA; 2Surgery, Temple University Hospital, Philadelphia, PA; 3Pulmonary & Critical Care, Temple University Hospital, Philadelphia, PA; 4Cardiothoracic Surgery, Temple University Hospital, Philadelphia, PA.

    PurposeTo evaluate the impact of alemtuzumab, basiliximab and no induction therapy on patient survival and chronic rejection.Methods3242 adult single lung transplantation from 2006 to 2013…
  • 2015 American Transplant Congress

    Cross-Linking of MHC Class I Induces Unique Transcriptional Profiles Associated With Regulation of Both T and B Cells That Precedes Induction of Allo- and Auto-Immunity Leading to Obliterative Airway Disease

    D. Nayak, M. Sharma, Z. Xu, A. Gelman, T. Mohanakumar.

    Surgery, Washington Univ Sch of Med, St. Louis, MO.

    Background: Incidences of chronic rejection, bronchiolitis obliterans syndrome (BOS), remain a major challenge to lung transplantation and development of allo- and auto-immunity has been proposed…
  • 2015 American Transplant Congress

    Lung Transplant Patients With Elevated Baseline Pulmonary Arterial Pressures Are More Likely to Recover from Post-Transplant Acute Kidney Injury

    B. Stephany,1 E. Wehbe,2 M. Budev.3

    1Nephrology & Hypertension, Cleveland Clinic, Cleveland, OH; 2Nephrology, Wichita, KS; 3Pulmonary, Allergy & Critical Care, Cleveland Clinic, Cleveland, OH.

    Purpose: Elevated pre-operative pulmonary arterial pressures predict acute kidney injury (AKI) after lung transplant. It is unknown if the elevated pulmonary pressures predict recovery from…
  • 2015 American Transplant Congress

    Do CMS Oversight and the Systems Improvement Agreement Really Change Institutional Behavior?

    C. Hoopes.

    Center for Transplantation and Organ Failure, University of kentucky, Lexington, KY.

    In 2010 the pulmonary transplant program at the University of Kentucky entered a Systems Improvement Agreement (SIA) with CMS as a consequence of poor performance…
  • 2015 American Transplant Congress

    Acute Kidney Injury After Lung Transplantation – Incidence, Risk Factors and Mechanisms

    F. Gueler,1 G. Warnecke,5 M. Peperhove,2 M.-S. Jang,1 C. Schroeder,3 S. Tewes,2 B. Wiese,6 C. Fegbeutel,5 R. Lichtinghagen,7 B. Jüttner,8 F. Wacker,2 D. Hartung,2 B. Akerstrom,4 M. Gram,4 H. Haller,1 A. Haverich,9 K. Hueper.2

    1Nephrology, Hannover Medical School, Hannover, Germany; 2Radiology, Hannover Medical School, Hannover, Germany; 3Proteomics, German Research Cancer Center, Heidelberg, Germany; 4Physiology, Lund University, Lund, Sweden; 5Thoracic and Cardiac Surgery, Hannover Medical School, Hannover, Germany; 6Medical Statistics, Hannover Medical School, Hannover, Germany; 7Laboratory Medicine, Hannover Medical School, Hannover, Germany; 8Anaesthesiology and Intensive Care Medicine, Hannover Medical School, Hannover, Germany; 9Cardiothoracic, Transplant and Vascular Surgery, Hannover Medical School, Hannover, Germany.

    Background: Acute kidney injury (AKI) is a frequent and severe complication after solid organ transplantation. In a retrospective analysis and afterwards in a prospective clinical…
  • 2015 American Transplant Congress

    Lung Transplantation from Donors With Kidney Disease

    A. Ganapathi, B. Gulack, A. Castleberry, R. Davis, L. Snyder, M. Hartwig.

    Duke University Medical Center, Durham, NC.

    Background:Various donor characteristics are associated with decreased survival following single (SLT) or bilateral (BLT) lung transplantation. No current studies exist regarding use of lungs from…
  • 2015 American Transplant Congress

    The Impact of High-Risk Lung Donors on the Survival of Lung Recipients With Interstitial Pulmonary Fibrosis

    P. Sanchez,1 M. Mulligan,1 C. Evans,1 I. Timofte,2 J. Kim,2 K. Rajagopal,1 A. Iacono,2 J. Gammie,1 R. Pierson III,1 B. Griffith,1 S. Pham.1

    1Cardiac Surgery, University of Maryland School of Medicine, Baltimore, MD; 2Medicine, University of Maryland School of Medicine, Baltimore, MD.

    Matching donors and recipients is largely based on experience. With the implementation of the LAS, IPF candidates have the highest provability of being transplanted after…
  • 2015 American Transplant Congress

    Pre-Existing Coronary Artery Disease in Lung Transplantat Recipients: Does It Impact Outcomes?

    S. Khandhar,1 L. Tefera,2 E. Volz,2 F. Selzer,3 R. Kormos,2 C. Bermudez.2

    1Heart and Vascular Institute at Penn-Presbyterian Medical Center, Perelman School of Medicine at University of Pennsylvania, Philadelphia, PA; 2Heart and Vascular Institute, University of Pittsburgh Medical Center, Pittsburgh, PA; 3Orthopaedic and Arthritis Center for Outcomes Research, Brigham and Womens Hospital, Boston, MA.

    INTRODUCTION:In patients undergoing lung transplantation (LTx), the impact of pre-existing coronary artery disease (CAD) on long-term outcomes is not well understood. This study examines the…
  • 2015 American Transplant Congress

    Broader Geographic Sharing of Adolescent Lung Donors Improves Allocation Efficiency

    W. Tsuang,1 J. Pyke,2 M. Skeans,2 K. Chan,4 T. Wozniak,3 A. Israni,2 M. Hertz,4 B. Kasiske,2 M. Valapour,1 J. Snyder.2

    1Cleveland Clinic, Cleveland, OH; 2SRTR, MMRF, Minneapolis, MN; 3IN University, Indianapolis, IN; 4University of MI, Ann Arbor, MI; 5University of MN, Minneapolis, MN.

    Allocating pediatric donor lungs to pediatric lung transplant (TXP) candidates results in better graft function. However, 87% of adolescent (ADL) donor lungs are allocated to…
  • 2015 American Transplant Congress

    High Atherosclerotic Burden in Pediatric Lung Transplant Recipients

    A. Melk,1 D. Thurn-Valsassina,1 N. Schwerk,2 F. Brinkmann,2 C. Mueller.2

    1Department of Pediatric Kidney, Liver and Metabolic Diseases, Hannover Medical School, Hannover, Germany; 2Department of Pediatric Pneumology and Neonatology, Hannover Medical School, Hannover, Germany.

    Purpose: Pediatric lung transplant patients have been reported to have an increased incidence of hypertension. This incidence might be caused by the treatment with calcineurin…
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