2018 American Transplant Congress
Circulating Exosomes with Lung Self-Antigens, Kα1Tubulin and Collagen V, and Immunoregulatory Molecules Are Present in Bronchiolitis Obliterans Syndrome Following Pediatric Lung Transplantation
Exosomes containing mismatched donor HLA and lung restricted self-antigens (SAgs), Kα1 Tubulin (Kα1T) and Collagen V (Col-V), have demonstrated in sera and bronchoalveolar lavage fluid…2018 American Transplant Congress
Incidence of Atrial Arrhythmia after Lung Transplantation with a Universal Prophylaxis Strategy
PurposePostoperative atrial arrhythmias (AA) occur in 19-39% of patients after lung transplantation and are associated with increased mortality, hospital length of stay, and risk of…2018 American Transplant Congress
Time and Perfusate Dependent Molecular Response in Ex Vivo Lung Perfusion
Lung transplantation has limited organ utilization and high rates of primary graft dysfunction, in part due to acute lung injury (ALI). Cold static preservation (CSP)…2018 American Transplant Congress
The Aggressive Phenotype: Center-Level Characteristics in the Use of Suboptimal Lungs
The disparity between organ supply and demand has led some centers to expand their criteria for donor selection. We explored utilization of suboptimal lungs to…2018 American Transplant Congress
Risk Factors for Postoperative Bleeding after Lung Transplantation
Bleeding complications after lung transplantation (LuTX) are associated with increased morbidity. Risk factors for postoperative bleeding complications after LuTX have not yet been reported. In…2018 American Transplant Congress
Characterization of Exosomal DNA from Human Lung Transplant Recipients
Norton Thoracic Institute, St. Joseph's Hosp & Med Ctr, Phoenix.
Exosomes are small vesicles which contains biological molecules including proteins, RNA`s and miRNAs. It has been reported that exosomes may contain ds DNA originated from…2018 American Transplant Congress
Pattern of Respiratory Virus Infection (RVI) and Chronic Lung Allograft Dysfunction (CLAD) in Lung Transplant Recipients (LTR)
University of ALberta, Edmonton, AB, Canada.
Background: The indirect effects of RVI in LTR are controversial. We aimed to define patterns of RVI in LTR and the impact on CLAD and…2018 American Transplant Congress
Simultaneous Persistence and Development of Donor and Recipient Tissue Resident Memory T Cells in Lung Transplantation
Introduction: The predominant T cell population in the lung comprises non-circulating tissue-resident memory T cells (TRM); however, the fate of these cells in transplanted lung…2018 American Transplant Congress
Superiority of Early Everolimus-Based Quadruple Immunosuppression versus Standard Triple Therapy after Lung Transplantation: 12 Months Results from Prospective 4EVERLUNG Study in Germany
The 4Everlung trial was designed to evaluate the benefit of early everolimus (EVR)-based quadruple low immunosuppressive (IS) regimen on kidney function (RF) after LTx.4EVERLUNG is…2018 American Transplant Congress
Identification of Exosomal Proteins from Human Lung Transplant Recipients
Molecular mechanisms involved in rejection following human lung transplantation are not well understood. Goal of this study is to identify proteomic signatures in the circulating…
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