2018 American Transplant Congress
Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis
Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…2018 American Transplant Congress
NK Cells with a Lung-Resident Phenotype Represent the Most Prominent Donor Passenger Leukocyte Subset after Clinical Lung Transplantation
ObjectivesDonor passenger leukocytes in peripheral blood of recipients after lung transplantation have been described long time ago. However, kinetics, distribution of T vs. NK cells,…2018 American Transplant Congress
Primary Oral Vancomycin Prophylaxis Reduces the Incidence of Clostridium difficile Infection among Lung Transplant Recipients
Cleveland Clinic Foundation, Cleveland, OH.
Purpose: To determine the efficacy of primary oral vancomycin prophylaxis in reducing the incidence of Clostridium difficile infection (CDI) in the early post-op period among…2018 American Transplant Congress
Prospective Trial Using Pulmonary Rehabilitation to Treat Frailty
Background: Frailty is a novel risk factor to potential lung transplant candidates and recipients associated with excess morbidity and mortality. Limited data is available on…2018 American Transplant Congress
CXCR4 Inhibition Improves Donor Leukocyte Depletion during Ex Vivo Lung Perfusion
Surgery, Duke University, Durham, NC.
Background: Ex vivo lung perfusion (EVLP) has emerged as a modern preservation technique, developed to evaluate candidate donor lungs in a normothermic and metabolically active…2018 American Transplant Congress
Gastroparesis after Lung Transplantation: A Single-Center Experience
Objective: Gastroparesis (GP), common in patients undergoing lung transplantation (LTx) for end-stage lung disease, can affect quality of life and absorbency of immunosuppressants. In this…2018 American Transplant Congress
Circulating Exosomes with Lung Self-Antigens, Kα1Tubulin and Collagen V, and Immune Regulatory Proteins in Lung Transplant Recipient with Primary Graft Dysfunction
Norton Thoracic Institute, St. Joseph's Hospital & Medical Center, Phoenix.
Background: Circulating exosomes isolated from lung transplant recipients (LTxRs) with acute or chronic rejection contains lung self-antigens (SAgs), K alpha 1 tubulin (Kα1T) and collagen…2018 American Transplant Congress
Most Pediatric Transplant Centers Are Underperforming and in Proximity to Higher Volume Centers
Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, TX.
Purpose. Many research studies have shown that low case volume has been associated with worse survival outcomes in each type of pediatric solid organ transplant.…2018 American Transplant Congress
Disparate Risk Factors for Early and Late Death Impact Survival after Lung Transplant
Cleveland Clinic, Cleveland, OH.
Purpose: After implementation of the lung allocation score, there has been improvement in one- and three-year survival but not in five-year survival after lung transplant…2018 American Transplant Congress
T-bet and STAT6 Double Deficiency Favors IL-17 Immunity after Lung Transplantation
Background: The long-term success of lung transplantation is mainly limited by the development of obliterative bronchiolitis (OB) in which IL-17 plays a critical role. Direct…
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