ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2018 American Transplant Congress

    Respiratory Viral Infections Induces Exosomes and Antibodies to Lung Self-Antigens, Kα1Tubulin and Collagen V, Following Human Lung Transplantation

    M. Gunasekaran,1 S. Bansal,1 M. Sharma,1 R. Walia,1 R. Hachem,2 A. Limaye,3 R. Bremner,1 M. Smith,1 T. Mohanakumar.1

    1St. Joseph's Hosp & Med Ctr, Phoenix; 2Washington Univ Sch Med, St. Louis; 3Univ Washington, Seattle.

    Respiratory viral infection (RVI) following human lung transplantation (LTx) increases the risk for chronic rejection. We demonstrated that lung transplant recipients (LTxR) with acute and…
  • 2018 American Transplant Congress

    The Impact of ABO Blood Type and Geography on Access to Lung Transplant

    W. Tsuang, D. McMichael, X. Wang, M. Budev.

    Cleveland Clinic, Cleveland.

    Background: Rare blood types (B and AB) are increasingly a risk factor for lung transplant waitlist mortality when compared to common blood types (A and…
  • 2018 American Transplant Congress

    Evaluation of Survival and Maintenance Immunosuppression in Elderly Lung Transplant Recipients

    P. Nguyen,1 R. Girgis,1,2 E. Murphy,1,2 R. Hadley,1,2 M. Leacche,1,2 A. Kumar,1,2 G. Sathiyamoorthy,1,2 J. McDermott.1,2

    1Spectrum Health, Grand Rapids, MI; 2Michigan State University College of Human Medicine, Grand Rapids, MI.

    Background: Lung transplantation in the elderly is controversial given increased risks and the optimal immunosuppression regimen is not fully understood.Methods: A retrospective cohort study was…
  • 2018 American Transplant Congress

    Broader Geographic Sharing and Impact on Lung Transplant Waitlist Time and Lung Allocation Score

    W. Tsuang, M. Budev.

    Cleveland Clinic, Cleveland.

    Background: Donor lungs are preferentially offered to patients within a local geographic area before being offered to a broader region. This algorithm may prevent patients…
  • 2018 American Transplant Congress

    Adjunctive Corticosteroid Immunosuppression Improves Hyperbilirubinemia Following Liver Transplantation (OLT)

    G. Malat, D. Reich, G. Xiao, M. Harhay, K. Ranganna, D. Lee, S. Guy, S. Munoz.

    Drexel University, Philadelphia.

    Background: Deceased donor orthotopic liver transplantation (OLT) can result in significant delayed function, manifesting as protracted hyperbilirubinemia, depending on the intensity of the ischemia/reperfusion injury…
  • 2018 American Transplant Congress

    Efficacy of Bronchoscopically-Administered Surfactant in the Setting of Primary Graft Dysfunction after Lung Transplantation

    S. Ahmed,1 M. Soto-Arenall,1 D. Jackson,1 D. Erasmus.2

    1Department of Pharmacy, Mayo Clinic in Florida, Jacksonville, FL; 2Department of Transplantation, Mayo Clinic in Florida, Jacksonville, FL.

    Primary graft dysfunction (PGD) is a severe form of ischemia and reperfusion acute lung injury presenting within the first 72 hours post-lung transplant. PGD is…
  • 2018 American Transplant Congress

    Heart and Lung Transplantation Outcomes in HIV-Positive Recipients

    C. Koval,1 M. Malinis,2 N. Mueller,3 J. Krisl,4 M. Hannan,5 P. Grossi,6 S. Huprikar.7

    1Infectious Diseases, Cleveland Clinic, Cleveland, OH; 2Infectious Diseases, Yale University, New Haven, CT; 3Infectious Diseases, University Hospital Zurich, Zurich, Switzerland; 4Pharmacy, Houston Methodist Hospital, Houston, TX; 5Infectious Diseases, Mater Hospital, Dublin, Ireland; 6Infectious Diseases, University Insubria, Varese, Italy; 7Infectious Diseases, Mount Sinai Hospital, New York, NY.

    Purpose: Data for HIV+ patients receiving heart (HT) or lung transplantation (LT) are limited but appear to demonstrate acceptable outcomes. We aimed to add to…
  • 2018 American Transplant Congress

    Reliability of Bronchiolitis Obliterans Syndrome Reporting to the OPTN

    R. Carrico,1 R. Lehman,1 K. Uccellini,1 K. Chan,2 T. Whelan.3

    1United Network for Organ Sharing, Richmond; 2Univ of Michigan, Ann Arbor; 3Medical Univ of South Carolina, Charleston.

    Background: Chronic rejection of the lung allograft is traditionally classified as bronchiolitis obliterans syndrome (BOS) diagnosed by obstructive airway physiology. The OPTN requires the reporting…
  • 2018 American Transplant Congress

    Using a Data Analytics Platform to Improve Patient Care in Pediatric Lung Transplantation

    B. Scully,1 K. Hosek,2 D. Dash,2 K. Carberry,1,2 E. Melicoff,3 M. Gazzaneo,3 G. Mallory,3 J. Heinle.1

    1Surgery, Baylor College of Medicine, Houston, TX; 2Outcomes and Impact Services, Texas Children's Hospital, Houston, TX; 3Pediatric Pulmonology, Baylor College of Medicine, Houston, TX.

    PurposeLung transplantation in children remains challenging, requiring extensive infrastructure and expertise. At our institution, we have performed 191 pediatric lung transplants since 2002. We hypothesized…
  • 2018 American Transplant Congress

    Immunity and Tolerance after Bilateral Orthotopic Lung Transplant (BOLT) in Tandem with a CD3+/CD19+ Depleted Vertebral Bone Marrow Transplant (BOLT+BMT) from 1 of 8 HLA-Matched Cadaveric Donors

    P. Szabolcs,1 X. Chen,1 A. Donnenberg,2 M. Hill,1 J. Rowan,1 S. Mcintyre,1 G. Kurland,1 J. Barnum,1 J. McDyer.1

    1BMT-CT, Children Hospital of Pittsburgh UPMC, Pittsburgh, PA; 2IDM-HCC, University of Pittsburgh, Pittsburgh, PA.

    Primary immunodeficiency patients may develop pulmonary complications and most are ineligible for either lung transplant or BMT due to futility. We report our first 2…
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