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Articles tagged "Lung transplantation"

  • 2019 American Transplant Congress

    Lung Transplantation in the Elderly Patients with Multi-Comorbidities

    N. Shigemura, Y. Toyoda

    Temple University Health System / Lewis Katz School of Medicine, Philadelphia, PA

    *Purpose: Recently there is an outstanding steadily increase in elderly patients above 70 years old who are referred to our center as potential candidates for…
  • 2018 American Transplant Congress

    EVLP on Donor Lungs: National Trends and Outcomes

    R. Lehman,1 R. Carrico,1 K. Uccellini,1 K. Chan,2 T. Whelan.3

    1United Network for Organ Sharing, Richmond, VA; 2Univ of Michigan, Ann Arbor, MI; 3Medical Univ of South Carolina, Charleston, SC.

    Purpose: The OPTN/UNOS added fields to the deceased donor registration form on 3/31/2015 to capture the intent to utilize ex vivo lung perfusion (EVLP) on…
  • 2018 American Transplant Congress

    Ex Vivo Lung Perfusion Using the Portable OCS Maintains Endothelial Integrity in the Context of Reduced Severe PGD Rates

    B. Wiegmann,1 R. BellmasSanz,2 C. Neudörfl,2 C. Kühn,1 I. Tudorache,1 M. Avsar,1 A. Haverich,1 G. Warnecke,1 C. Falk.2

    1Department of Cardiothoracic, Transplantation, Vascular Surgery, Hannover Medical School, Hannover, Germany; 2Institute of Transplant Immunology, Hannover Medical School, Hannover, Germany.

    PurposeThe INSPIRE trial revealed significant reduction of PGD grade 3, i.e. less ischemia reperfusion injury (IRI) using the Organ Care System (OCS) compared to controls…
  • 2018 American Transplant Congress

    Surveillance for Mycoplasma/Ureaplasma Infection in Lung Transplant Recipients (LTRs)

    L. Somerville, W. Sligl, N. Zelyas, D. Lien, J. Preiksaitis.

    University of Alberta, Edmonton, AB, Canada.

    Introduction: An association with Ureplasma urealyticum, Ureaplasma parvum and Mycoplasma hominis infections has been proposed to play a causative role in hyperammonemia syndrome (HS), a…
  • 2018 American Transplant Congress

    A Cost Analysis on Normothermic Machine Perfusion at a Single Center

    D. Pezzati, Q. Liu, H. Hassan, G. Iuppa, L. Hernandez, G. D'Amico, T. Diago Uso, B. Heghtsad, C. Miller, C. Quintini.

    General Surgery, Cleveland Clinic, Cleveland, OH.

    INTRODUCTION: Normothermic machine perfusion (NMP) for liver transplantation is a novel and promising technique.One of the concerns related to its usage is the high cost.The…
  • 2018 American Transplant Congress

    Increase in Potentially Resistant Non-Aspergillus Molds Isolated in Lung Transplant Recipients after Voriconazole and Posaconazole Prophylaxis

    M. Fung,1 J. Greenland,2,3 S. Hays,2 J. Singer,2 J. Golden,2 P. Chin-Hong.1

    1Infectious Diseases, University of California San Francisco, San Francisco, CA; 2Pulmonary and Critical Care, University of California San Francisco, San Francisco, CA.

    Background: Lung transplant recipients are at higher risk for invasive fungal infections compared to other solid organs transplant patients. Antifungal prophylaxis with mold-active azoles has…
  • 2018 American Transplant Congress

    NK Cells with a Lung-Resident Phenotype Represent the Most Prominent Donor Passenger Leukocyte Subset after Clinical Lung Transplantation

    C. Falk,1 R. BellmasSanz,1 B. Wiegmann,2 A-.M. Hitz,1 K. Bläsing,1 C. Neudörfl,1 I. Tudorache,2 C. Kühn,2 M. Avsar,2 A. Haverich,2 G. Warnecke.2

    1Institute of Transplant Immunology, IFB-Tx, Hannover Medical School, Hannover, Germany; 2Department of Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School, Hannover, Germany.

    ObjectivesDonor passenger leukocytes in peripheral blood of recipients after lung transplantation have been described long time ago. However, kinetics, distribution of T vs. NK cells,…
  • 2018 American Transplant Congress

    Primary Oral Vancomycin Prophylaxis Reduces the Incidence of Clostridium difficile Infection among Lung Transplant Recipients

    V. Bajrovic, K. Brizendine.

    Cleveland Clinic Foundation, Cleveland, OH.

    Purpose: To determine the efficacy of primary oral vancomycin prophylaxis in reducing the incidence of Clostridium difficile infection (CDI) in the early post-op period among…
  • 2018 American Transplant Congress

    Prospective Trial Using Pulmonary Rehabilitation to Treat Frailty

    C. Kennedy,1 P. Novotny,2 E. Stevens,1 J. Kirsch,3 J. Garrett,1 N. LeBrasseur,4 R. Benzo.1

    1Pulmonary and Critical Care Medicine, Mayo Clinic, Rochester, MN; 2Health Sciences Research, Mayo Clinic, Rochester, MN; 3Clinical and Health Psychology, University of FL, Gainesville, FL; 4Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN.

    Background: Frailty is a novel risk factor to potential lung transplant candidates and recipients associated with excess morbidity and mortality. Limited data is available on…
  • 2018 American Transplant Congress

    CXCR4 Inhibition Improves Donor Leukocyte Depletion during Ex Vivo Lung Perfusion

    R. Davis, Q. Gao, J. Yerxa, M. Daneshmand, J. Haney, J. Klapper, M. Hartwig, A. Barbas.

    Surgery, Duke University, Durham, NC.

    Background: Ex vivo lung perfusion (EVLP) has emerged as a modern preservation technique, developed to evaluate candidate donor lungs in a normothermic and metabolically active…
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