2019 American Transplant Congress
Examination of a Novel Immunoregulatory Marker in Kidney and Lung Transplant Recipients
*Purpose: The T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (TIGIT) is a co-inhibitory receptor mainly expressed on T cells and NK cells. TIGIT has…2018 American Transplant Congress
Broader Geographic Sharing and Impact on Lung Transplant Waitlist Time and Lung Allocation Score
Background: Donor lungs are preferentially offered to patients within a local geographic area before being offered to a broader region. This algorithm may prevent patients…2018 American Transplant Congress
Adjunctive Corticosteroid Immunosuppression Improves Hyperbilirubinemia Following Liver Transplantation (OLT)
Drexel University, Philadelphia.
Background: Deceased donor orthotopic liver transplantation (OLT) can result in significant delayed function, manifesting as protracted hyperbilirubinemia, depending on the intensity of the ischemia/reperfusion injury…2018 American Transplant Congress
Efficacy of Bronchoscopically-Administered Surfactant in the Setting of Primary Graft Dysfunction after Lung Transplantation
Primary graft dysfunction (PGD) is a severe form of ischemia and reperfusion acute lung injury presenting within the first 72 hours post-lung transplant. PGD is…2018 American Transplant Congress
Heart and Lung Transplantation Outcomes in HIV-Positive Recipients
Purpose: Data for HIV+ patients receiving heart (HT) or lung transplantation (LT) are limited but appear to demonstrate acceptable outcomes. We aimed to add to…2018 American Transplant Congress
Reliability of Bronchiolitis Obliterans Syndrome Reporting to the OPTN
Background: Chronic rejection of the lung allograft is traditionally classified as bronchiolitis obliterans syndrome (BOS) diagnosed by obstructive airway physiology. The OPTN requires the reporting…2018 American Transplant Congress
Using a Data Analytics Platform to Improve Patient Care in Pediatric Lung Transplantation
PurposeLung transplantation in children remains challenging, requiring extensive infrastructure and expertise. At our institution, we have performed 191 pediatric lung transplants since 2002. We hypothesized…2018 American Transplant Congress
Immunity and Tolerance after Bilateral Orthotopic Lung Transplant (BOLT) in Tandem with a CD3+/CD19+ Depleted Vertebral Bone Marrow Transplant (BOLT+BMT) from 1 of 8 HLA-Matched Cadaveric Donors
Primary immunodeficiency patients may develop pulmonary complications and most are ineligible for either lung transplant or BMT due to futility. We report our first 2…2018 American Transplant Congress
Circulating Exosomes with Lung Self-Antigens, Kα1Tubulin and Collagen V, and Immunoregulatory Molecules Are Present in Bronchiolitis Obliterans Syndrome Following Pediatric Lung Transplantation
Exosomes containing mismatched donor HLA and lung restricted self-antigens (SAgs), Kα1 Tubulin (Kα1T) and Collagen V (Col-V), have demonstrated in sera and bronchoalveolar lavage fluid…2018 American Transplant Congress
Incidence of Atrial Arrhythmia after Lung Transplantation with a Universal Prophylaxis Strategy
PurposePostoperative atrial arrhythmias (AA) occur in 19-39% of patients after lung transplantation and are associated with increased mortality, hospital length of stay, and risk of…
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