Articles tagged "Lung transplantation"

2019 American Transplant Congress
Frailty is Highly Prevalent in Lung Transplant Candidates and Varies by Frailty Tool
A. O'Boye, K. Leitner, M. Kelly, J. Wright, J. Lee, M. Sala, R. Tomic, S. Bhorade
Northwestern Memorial Hospital, Chicago, IL
*Purpose: Lung transplantation is a lifesaving therapy in patients with advanced lung disease. However, frail lung transplant candidates are more likely to be delisted or…
2019 American Transplant Congress
The Burden of Recipient Driving Distance and Post Lung Transplant Outcomes: A National Cohort Study
W. Tsuang, S. Arrigain, R. Lopez, M. Snair, K. McCurry, M. Budev, J. Schold
Cleveland Clinic, Cleveland, OH
*Purpose: There are only 75 lung transplant centers in the United States, which leads to a spectrum of travel burdens among patients in order to…
2019 American Transplant Congress
Assessment of the Global Practice of Pediatric Living Donor Liver Transplantation: Comparison of U.S. and International Programs
J. Emamaullee¹, M. Kim¹, C. Conrad¹, C. Lane¹, P. Singh¹, C. Niemann², L. Sher¹, Y. Genyk¹
¹University of Southern California, Los Angeles, CA, ²University of California-San Francisco, San Francisco, CA
*Purpose: As programs have become more experienced with living donor liver transplantation (LDLT), technical hurdles have been overcome and superior graft and patient survival has…
2019 American Transplant Congress
Correlation between Gene Expression and Histology in Transbronchial Lung Transplant Biopsies
B. Adam, K. Du, S. Rotich, M. Mengel
University of Alberta, Edmonton, AB, Canada
*Purpose: Transbronchial lung transplant biopsies (TBBx) are limited by non-specific histologic lesions and suboptimal interobserver reproducibility. Gene expression offers a potentially more precise, objective and…
2019 American Transplant Congress
Inadequate (ax) Transbronchial Biopsies Are Not Associated With Clad Or Death After Lung Transplantation
L. Levy¹, E. Huszti², J. Tikkanen³, R. Ghany³, S. Keshavjee³, T. Martinu³
¹Lung Transplant Program, University Health Network, University of Toronto, Toronto, ON, Canada, ²Biostatistics Research Unit, University Health Network, University of Toronto, Toronto, ON, Canada, ³Lung transplant Program, University Health Network, University of Toronto, Toronto, ON, Canada
*Purpose: Acute cellular rejection (ACR) in lung transplantation is defined by perivascular and interstitial mononuclear infiltrates on lung allograft pathology. Procuring a good quality transbronchial…
2019 American Transplant Congress
Lung Transplant Outcomes after CABG
S. Huddleston¹, R. Aggarwal¹, S. Jackson², N. Lemke¹
¹Surgery, University of Minnesota, Minneapolis, MN, ²Surgery, Fairview Health Services, Minneapolis, MN
*Purpose: Prior coronary artery bypass grafting (CABG) has been a contraindication to lung transplantation (LTx) due to increased mortality associated with bilateral lung transplant. We…
2019 American Transplant Congress
Circulating Donor T and NK Cells in Lung Transplantation Recipients Are Derived from the Donor Lung Parenchyma and Represent Tissue-Resident Memory Cells
J. F. Kuehne¹, R. Ballmàs Sanz¹, A. Hitz¹, B. Wiegmann², K. A. Bläsing¹, F. Ius², A. Knoefel², I. Tudorache², M. Avsar², D. Jonigk³, A. Haverich², G. Warnecke², C. Falk¹
¹Institute of Transplant Immunology, Hannover Medical School (MHH), Hannover, Germany, ²Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover Medical School (MHH), Hannover, Germany, ³Institute of Pathology, Hannover Medical School (MHH), Hannover, Germany
*Purpose: We previously identified donor lymphocytes in peripheral blood of recipients directly after transplantation and persisting at least three weeks that were characterized by the…
2019 American Transplant Congress
Molecular Features of Rejection in Endobronchial Mucosa Biopsies
M. D. Parkes, K. M. Halloran, J. Chang, P. F. Halloran and The INTERLUNG Study Group
University of Alberta, Edmonton, AB, Canada
*Purpose: Mucosal biopsies are safer and easier to collect than transbronchial biopsies (TBB) but cannot be assessed histologically for lung rejection. Reliable assessment would change…
2019 American Transplant Congress
Effect of Donor-Recipient Serologic CMV Matching on 1-Year Post-Lung Transplant Outcomes
H. Ehrenfeld, M. Manson, R. Yau
Pharmacy, CHI St. Luke's Health Baylor St. Luke's Medical Center, Houston, TX
*Purpose: Cytomegalovirus (CMV) poses significant risks and complications in solid organ transplant (SOT) patients. The current CMV guidelines acknowledge CMV serologic mismatch transplants contribute to…
2019 American Transplant Congress
Center Variability in Organ Offer Acceptance and Waitlist Mortality in Lung Transplantation
A. Y. Choi¹, M. S. Mulvihill², J. Weber³, H. Lee³, M. Cox², B. Yerokun², M. Kuchibhatla³, J. A. Klapper², M. G. Hartwig²
¹Duke University School of Medicine, Durham, NC, ²Department of Surgery, Duke University Medical Center, Durham, NC, ³Department of Biostatistics and Bioinformatics, Duke University School of Medicine, Durham, NC
*Purpose: Lung transplantation (LTx) offers a survival benefit for patients with end-stage lung disease. When suitable donors are identified, centers must accept or decline the…