Articles tagged "Lung transplantation"

2020 American Transplant Congress
Clinical Evaluation of Lung Transplantation for End-Stage Idiopathic Pulmonary Fibrosis Patients with Lung Cancer
J. Zhang, D. Liu, J. Chen
Lung Transplant Center, Wuxi People's Hospital, Wuxi, China
*Purpose: The treatment of patients with end-stage idiopathic pulmonary fibrosis (IPF) and lung cancer (LC) is a difficult task, and it remains questionable whether LC…
2019 American Transplant Congress
Association between Respiratory Virus Infections and the Development of De Novo HLA Donor-Specific Antibodies in Lung Transplant Recipients
M. I. Ali, J. Hata, J. Mallea, M. Elrefaei
Mayo Clinic, Jacksonville, FL
*Purpose: The detection of de novo donor-specific anti-HLA antibodies (DSA) post lung transplant have been associated with significantly increased risk for antibody-mediated rejection (AMR) and…
2019 American Transplant Congress
Induction Type Does Not Influence Kidney Graft or Patient Survival in Recipients with a Previous Lung Transplant in the United States
S. Riad¹, U. Goswami², S. Jackson³, M. Hertz²
¹Medicine, University of Minnesota, Eden Prairie, MN, ²Medicine, University of Minnesota, Minneapolis, MN, ³Complex Care Analytics, Fairview Health Services, Minneapolis, MN
*Purpose: Induction regimens for kidney transplant alone (KT) in lung recipients vary widely among transplant centers. We sought to examine the impact of kidney induction…
2019 American Transplant Congress
Synergistic Effect of HLA Eplet Mismatch Load and CMV Viremia on Clinical Antibody-Mediated Rejection in Lung Transplantation
Y. Im¹, S. Yeramaneni², Y. Yim³, J. Dodderer⁴, M. Askar¹, H. J. Huang⁵
¹Baylor University Medical Center, Dallas, TX, ²Baylor Scott & White Health, Dallas, TX, ³Ross University School of Medicine, Portsmouth, Dominica, ⁴Texas Tech University Health Sciences Center, El Paso, TX, ⁵Houston Methodist Hospital, Houston, TX
*Purpose: De novo donor specific antibodies (dnDSA) occur in up to 50% of lung transplant (LUTX) recipients within one year and are associated with increased…
2019 American Transplant Congress
Ex-Vivo Perfusion Mediated Delivery of Rituximab to Clear Latent Epstein-Barr Virus
T. Ku, M. Cypel, R. V. Ribeiro, V. H. Ferreira, D. Kumar, A. Humar
UHN, Toronto, ON, Canada
*Purpose: Post-transplant lymphoproliferative disorder (PTLD) can manifest as a B-cell malignancy associated with Epstein-Barr virus (EBV) infection. Risk of PTLD is greatest in EBV D+/R-…
2019 American Transplant Congress
Polymorphisms in Mycophenolate Mofetil Glucuronidation Gene Are Associated with Leukopenia and Decreased CLAD-Free Survival
A. Barnes, D. R. Calabrese, E. Henricksen, R. Florez, K. Dewey, P. Wang, J. Teraoka, K. Lien, S. Hays, J. P. Singer, J. Golden, J. Kukreja, J. R. Greenland
UCSF Medical Center, San Francisco, CA
*Purpose: Lung transplant recipients vary in their tolerance of the immunosuppressant mycophenolate mofetil (MMF). Single nucleotide polymorphisms (SNPs) in UDP-glucuronosyltransferase 2B7 (UGT2B7) increase conversion of…
2019 American Transplant Congress
Alteration in Local Complement Activation in First 24h Post-Lung Transplantation (LTx) Helps Identify Recipients Developing Primary Graft Dysfunction
H. Kulkarni¹, M. Elvington², L. Ma¹, M. Cano¹, K. Pugh³, R. Hachem¹, J. Atkinson², A. Gelman³
¹Pulmonary and Critical Care Medicine, Washington University, Saint Louis, MO, ²Rheumatology, Washington University, Saint Louis, MO, ³Surgery, Washington University, Saint Louis, MO
*Purpose: Primary graft dysfunction (PGD) is a form of acute lung injury driven by ischemia-reperfusion mediated damage. An increase in plasma complement proteins - specifically…
2019 American Transplant Congress
Comparison of Basiliximab and Alemtuzumab for Lung Transplant Induction
S. Mietz¹, D. Roe², E. Lushin¹, E. Anderson¹, C. Hage²
¹Pharmacy, Indiana University Health, Indianapolis, IN, ²Pulmonary Critical Care, Indiana University Health, Indianapolis, IN
*Purpose: Compare alemtuzumab and basiliximab used for lung transplant in terms of rejection, CLAD, and mortality.*Methods: A retrospective review of lung transplants performed between 2010…
2019 American Transplant Congress
Opioid and Benzodiazepine Use in Lung Transplant Candidates: A National Survey of Policies and Practices
H. Bruschwein¹, V. Andersen¹, H. Patel², J. Fleming³, A. Shahane¹, M. Weder¹
¹University of Virginia, Charlottesville, VA, ²University of North Carolina, Chapel Hill, NC, ³Medical University of South Carolina, Charleston, SC
*Purpose: The opioid epidemic has raised the question of how transplant teams should work with patients who are prescribed opioids. Benzodiazepine use has also received…
2019 American Transplant Congress
Improving Access to Lung Transplant through Donor Strategy: A Decision Analysis
W. Tsuang, B. Udeh
Cleveland Clinic, Cleveland, OH
*Purpose: The use of Donation after Cardiac Death (DCD) donors in addition to Donation after Brain Death (DBD) donors may increase patient access to lung…