ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Lung transplantation"

  • 2020 American Transplant Congress

    Single Center Snapshot Experience of dd-cfDNA in Lung Transplantation

    D. Levine, P. Ong, D. De Armond, E. Sako

    University of Texas Health San Antonio, San Antonio, TX

    *Purpose: Chronic lung allograft dysfunction (CLAD) is the primary etiology of graft failure and associated with poor survival post lung transplantation (LT). Risk factors for…
  • 2019 American Transplant Congress

    Circulating Exosomes Isolated from Human Lung Transplant Recipients with Respiratory Viral Infections Contain Nucleic Acids Specific to Virus and Can Lead to Activation of Stress Proteins

    S. Bansal, R. Bremner, M. Smith, T. Mohanakumar

    Norton Thoracic Institute, St. Joseph’s Hospital and Medical Center, Phoenix, AZ

    *Purpose: Exosomes are membrane vesicles released by cells into body fluids. Our laboratory demonstrated the presence of circulating exosomes with lung self-antigens (SAgs), Collagen V…
  • 2019 American Transplant Congress

    A Randomized Pilot Trial of Home-Based Physical Activity Plus Dietary Intervention to Improve Physical Function in Patients with Advanced Liver Disease

    H. Chen1, A. A. Ferrando2, M. G. White2, M. Pauly2, T. Bartter2, M. A. Dunn1, W. R. Kim3, A. Duarte-Rojo1

    1T.E. Starzl Transplantation Institute, University of Pittsburgh Medical Center, Pittsburgh, PA, 2University of Arkansas for Medical Sciences, Little Rock, AR, 3Stanford University, Palo Alto, CA

    *Purpose: Deconditioning and frailty are prevalent among liver transplant (LTx) candidates and prehabilitation programs have been proposed in order to improve clinical outcomes. However, few…
  • 2019 American Transplant Congress

    The Molecular Features of Chronic Lung Allograft Dysfunction (CLAD) in Transbronchial and Endobronchial Mucosa Biopsies

    M. D. Parkes1, K. M. Halloran1, J. Chang2, P. F. Halloran and the INTERLUNG study group1

    1University of Alberta, Edmonton, AB, Canada, 2ATAGC, University of Alberta, Edmonton, AB, Canada

    *Purpose: Chronic lung allograft dysfunction (CLAD), the major long-term problem in lung transplantation, requires new strategies for prevention and management. However, CLAD is infrequently diagnosed…
  • 2019 American Transplant Congress

    Caregiving in Thoracic Transplantation–A SR/MA

    A. A. Rmilah, J. Lau, R. Mendpara, P. Erwin, C. C. Kennedy

    Mayo Clinic, Rochester, MN

    *Purpose: Caregivers are required for heart and lung transplantation, however, little emphasis is placed on the pre-transplant caregiving experience. Our objective was to perform a…
  • 2019 American Transplant Congress

    Bronchoalveolar Lavage Biomarkers Predict Lung Transplant Survival

    A. Zarinsefat1, J. Y. Yang2, R. Sarwal1, J. Liberto1, D. Watson3, S. Verleden4, M. Sarwal1

    1UC San Francisco, San Francisco, CA, 2Johns Hopkin, Baltimore, MD, 3Kit Bio, Los Altos, CA, 4KU Leuven, Leuven, Belgium

    *Purpose: In lung transplants (LTx), chronic rejection remains a major cause of morbidity and mortality following transplantation, mainly from chronic lung allograft dysfunction (CLAD). Two…
  • 2019 American Transplant Congress

    Syphilis Transmission in Solid Organ Transplantation

    M. Morrison, M. Hurtik, G. M. Lyon, S. Pouch

    Emory University Hospital, Atlanta, GA

    *Purpose: Syphilis is a sexually transmitted infection that affects people worldwide. While transmission generally occurs via sexual contact, other modes of transmission are possible, including…
  • 2019 American Transplant Congress

    Azole Use and Fungal Pathogens in Cystic Fibrosis versus Non-Cystic Fibrosis Lung Transplant Recipients

    F. J. Marco Canosa1, K. Brizendine2, H. Hassouna3

    1Internal Medicine, Cleveland Clinic Foundation, Cleveland, OH, 2Infectious Disease, Cleveland Clinic Foundation, Cleveland, OH, 3Infectious Disease, Spectrum Health Infectious Disease, Grand Rapids, MI

    *Purpose: Cystic fibrosis (CF) patients exhibit unique pharmacokinetic principles. Azole antifungals show marked inter- and intra-patient variability. We aimed to improve itraconazole (ITR) use and…
  • 2019 American Transplant Congress

    Not All Donor-Specific Antibodies Are Equal: Predictors of Risk of Chronic Lung Allograft Dysfunction

    C. J. Iasella1, C. R. Ensor2, M. Marrari3, M. Mangiola3, C. A. Moore1, M. R. Morrell4, J. Pilewski4, J. F. McDyer4, A. Zeevi3

    1Pharmacy and Therapeutics, University of Pittsburgh, Pittsburgh, PA, 2Florida Hospital Transplant Institute, AdventHealth Orlando, Orlando, FL, 3Pathology, University of Pittsburgh, Pittsburgh, PA, 4Medicine, University of Pittsburgh, Pittsburgh, PA

    *Purpose: Donor-specific HLA antibodies (DSA) have been previously associated with chronic lung allograft dysfunction (CLAD). However, the DSA characteristics that predict risk of CLAD are…
  • 2019 American Transplant Congress

    Impact of Multidrug-Resistant Microbes of Donor Lower Respiratory Tract on Early Posttransplant Pneumonia in Bilateral Lung Transplant Recipients without Pretransplant Infection

    S. HAN1, S. Kim2, M. Park3, J. Lee4, H. Paik4

    1Internal Medicine, Yonsei University Health System, Yonsei University College of Medicine, Seoul, Korea, Republic of, 2Internal Medicine, Yonsei University Health SystemYonsei University Health System, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea, Republic of, 3Internal Medicine, Yonsei University Health System, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea, Republic of, 4Chest Surgery, Yonsei University Health System, Yonsei University College of Medicine, Severance Hospital, Seoul, Korea, Republic of

    *Purpose: Colonized microbes in lower respiratory tract (LRT) of deceased donor allograft can potentially cause early posttransplant pneumonia (EPTP) that leads to detrimental outcome in…
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