Articles tagged "Lung transplantation"

2020 American Transplant Congress
The Impact of Thy1 Expression of Fibroblast for Chronic Lung Allograft Dysfunction
A. Hata¹, Y. Guo¹, D. Li¹, Z. Mei¹, A. Manafi¹, A. Banerjee¹, B. Mahgoub¹, T. H. Barker², A. S. Krupnick¹
¹Surgery, University of Virginia, Charlottesville, VA, ²Biomedical Engineering, University of Virginia, Charlottesville, VA
*Purpose: Chronic lung allograft dysfunction (CLAD) result from excessive immune activation and excessive collagen deposition by fibroblasts within the lung parenchyma or airway.Bronchiolitis obliterans (OB)…
2020 American Transplant Congress
A Survey of Lung Transplant Recipient Attitudes and Beliefs on Accepting an Organ That Was Positive for Hepatitis C Virus
S. S. Humar¹, N. Pinzon¹, M. Cypel¹, S. Abbey²
¹University Health Network, Transplant Center, Toronto, ON, Canada, ²University Health Network, Center for Mental Health, Toronto, ON, Canada
*Purpose: Recent data show that organs from donors who are HCV positive (+ve) can be safely transplanted into HCV negative recipients. We conducted a survey…
2020 American Transplant Congress
Use of 16S Sequencing to Reveal Potential Respiratory Pathogens in Lung Transplant Recipients
C. Eskind¹, M. Shilts¹, H. Boone¹, J. Schmitz², C. Shaver³, S. Das¹, G. Satyanarayana¹
¹Infectious Diseases, Vanderbilt University Medical Center, Nashville, TN, ²Pathology, Microbiology and Immunology, Vanderbilt University Medical Center, Nashville, TN, ³Allergy, Pulmonary, and Critical Care Medicine, Vanderbilt University Medical Center, Nashville, TN
*Purpose: Respiratory infections are common after lung transplant and contribute to mortality and allograft failure. 16S ribosomal RNA (rRNA) gene sequencing could facilitate diagnosis of…
2020 American Transplant Congress
Lung Mucosal Biopsies Deteriorate with Time Post-Transplant: A Molecular Analysis
M. D. Parkes¹, P. Halloran¹, K. Halloran², &. the INTERLUNG Study Group³
¹Alberta Transplant Applied Genomics Centre, Edmonton, AB, Canada, ²University of Alberta, Edmonton, AB, Canada, ³., ., AB, Canada
*Purpose: Mucosal biopsies from the third airway bifurcation (3BMBs) assessed molecularly can be used to detect rejection (DOI: 10.1111/ajt.15685), and may also provide insights into…
2020 American Transplant Congress
The Study of Continuous Renal Replacement Therapy Performing in Pre-Retrieval Management of Marginal Criteria Donor Lung: A Retrospective Control Study
J. Huang¹, X. Zheng², Z. Wang¹, M. Huang², J. Chen¹
¹Wuxi Lung Transplant Center, Wuxi People's Hospital affiliated to Nanjing Medical University, Wuxi, China, ²General ICU, Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China
*Purpose: Ex vivo lung perfusion (EVLP) has successfully been applied to the management of marginal donor lungs, while the high cost and equipment lacking restrict…
2020 American Transplant Congress
Clinical Evaluation of Lung Transplantation for End-Stage Idiopathic Pulmonary Fibrosis Patients with Lung Cancer
J. Zhang, D. Liu, J. Chen
Lung Transplant Center, Wuxi People's Hospital, Wuxi, China
*Purpose: The treatment of patients with end-stage idiopathic pulmonary fibrosis (IPF) and lung cancer (LC) is a difficult task, and it remains questionable whether LC…
2020 American Transplant Congress
Impact of Ozone Exposure of Lung Donors and Recipients on All-Cause Mortality after Lung Transplant
T. Egan¹, S. Arunachalam², C. Chang², P. Strassle¹
¹Surgery, UNC at Chapel Hill, Chapel Hill, NC, ²Institute of the Environment, UNC at Chapel Hill, Chapel Hill, NC
*Purpose: A Belgian study found proximity to a motorway increased risk of bronchiolitis obliterans syndrome after lung transplant (LT). Using zip codes as a surrogate…
2020 American Transplant Congress
Anticipated Cost Savings of Using Lungs from Hepatitis C-Positive Lung Donors for Hepatitis C-Negative Recipients
K. Ryland¹, J. Mallea², J. Moriarty³, L. White⁴, B. Borah⁵, J. Naessens³
¹Transplantation, Mayo Clinic, Jacksonville, FL, ²Medicine, Mayo Clinic, Jacksonville, FL, ³Kern Center for the Science of Health Care Delivery, Mayo Clinic, Rochester, MN, ⁴Health Sciences Research, Mayo Clinic, Jacksonville, FL, ⁵Health Sciences Research, Mayo Clinic, Rochester, MN
*Purpose: We assessed the cost savings generated by additional organ availability due to utilizing lungs from hepatitis-C infected donors for transplantation in comparison to existing…
2020 American Transplant Congress
Analysis of the Quality of Lung Transplantation in Mainland China During 2015- 2018
H. Chun Xiao, L. Xiao Shan, C. Jing Yu
Wuxi Lung Transplant Center, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China
*Purpose: Lung Transplantation(LT)has been demonstrated as the only effective therapy for patients with end-stage lung diseases. This study aimed to summarize and analyze the data…
2020 American Transplant Congress
Epidemiology of Invasive Candidiasis in Lung Transplant Recipients at a Large Transplant Center
F. J. Marco Canosa¹, J. A. Morillas¹, H. Hassouna², K. Brizendine¹
¹Infectious Disease Department, Cleveland Clinic Foundation, Cleveland, OH, ²Division of Infectious Disease, Spectrum Health Medical Group, Grand Rapids, MI
*Purpose: Invasive candidiasis (IC) represents the most common fungal infection in lung transplant recipients (LTR) early post-transplant. Universal antifungal prophylaxis is frequently employed, which may…