Articles tagged "Lung transplantation"

2021 American Transplant Congress
Acute Kidney Injury After Lung Transplantation: Incidence, Risk Factors and Outcomes. Results from a Monocentric Retrospective Cohort Study
M. Gandolfo¹, C. Bellincioni¹, L. Morlacchi², V. Rossetti², F. Blasi², P. Messa¹
¹Nephrology, Ospedale Maggiore Policlinico, Milano, Italy, ²Pneumology, Ospedale Maggiore Policlinico, Milano, Italy
*Purpose: Acute kidney Injury (AKI) occurs in more than 50% of patients after lung transplantation (LTx). Our purpose was to define incidence, risk factors and…
2021 American Transplant Congress
Impact Analysis of Virtual Transplant Ambulatory Pharmacist During Covid-19
L. Park, G. Waldman, J. Kim, C. Rogers, J. Clark
Massachusetts General Hospital, Boston, MA
*Purpose: During the COVID-19 pandemic, transplant centers were challenged to meet the demand for new telemedicine strategies. High-risk immunocompromised patients, such as lung transplant recipients…
2021 American Transplant Congress
Donor T and NK Cells with a Special Tissue-Resident Memory Phenotype Migrate Into the Periphery of Lung Transplant Recipients – A Potential Feature for Tolerance Development
L. M. Ruhl¹, R. Bellmàs Sanz¹, A. Hitz¹, B. Wiegmann², K. A. Bläsing¹, W. Sommer², F. Ius², J. F. Kühne¹, A. Knöfel², L. M. Horn¹, I. Tudorache², A. Haverich², D. Jonigk³, G. Warnecke², C. S. Falk¹
¹MHH, Institute of Transplant Immunology, Hannover, Germany, ²MHH, Department for Cardiothoracic, Transplantation and Vascular Surgery, Hannover, Germany, ³MHH, Institute of Pathology, Hannover, Germany
*Purpose: After lung transplantation (LuTx), a transient chimerism of donor cells exists in the blood of recipients due to the migration of lymphocytes from the…
2021 American Transplant Congress
Lung Transplantation After Ex-Vivo Lung Perfusion versus Static Cold Storage: A Single Institution Cost Analysis
S. E. Halpern¹, S. J. Kesseli², S. Au¹, M. K. Krischak¹, D. G. Olaso¹, H. Smith³, G. Tipton², I. Jamieson³, J. C. Haney², J. A. Klapper², M. G. Hartwig²
¹Duke University School of Medicine, Durham, NC, ²Surgery, Duke University Medical Center, Durham, NC, ³Office of Finance, Duke Transplant Center, Durham, NC
*Purpose: Ex-vivo lung perfusion (EVLP) allows for reconditioning of “marginal” lung grafts and extended lung preservation. However, EVLP is costlier than cold storage. We compared…
2021 American Transplant Congress
Outcomes of IVIG Monotherapy for Donor-Specific Antibodies After Lung Transplantation
K. Spence, S. Heeney, M. Morrison, S. A. Rega, F. D. Irene, K. B. Harrison, C. M. Shaver
Vanderbilt University Medical Center, Nashville, TN
*Purpose: De novo donor-specific antibodies (DSA) are a risk factor for antibody mediated rejection (AMR) and poor clinical outcomes after lung transplant (LT). Intravenous immune…
2021 American Transplant Congress
HTFPI.hCD47 and Adhesion Inhibition in GTKO.hCD46 Pig Lung Xenograft Injury
S. Miura¹, L. Burdorf¹, Z. Habibabady¹, A. Dandro², M. Connolly¹, S. Pratts¹, C. Phelps², W. Eyestone², D. Ayares², A. Azimzadeh¹, R. Pierson III¹
¹Center for Transplantation Sciences, Massachusetts General Hospital, Charlestown, MA, ²Revivicor, Inc, Blacksburg, VA
*Purpose: We evaluate whether genetic expression of human tissue factor pathway inhibitor (TFPI, extrinsic coagulation pathway inhibitor) and human CD47 ("don’t eat me" immunoregulator), alone…
2021 American Transplant Congress
Pre-Procurement Cardiac Arrest in Lung Allograft Donors and Effects on Recipient Outcomes
T. J. Hathaway, E. C. Klipsch, D. Roe, C. Hage, M. Duncan, R. S. Mangus
Indiana University School of Medicine, Indianapolis, IN
*Purpose: This study seeks to help expand the lung transplant donor pool by demonstrating the safe use of lung allografts from donors who underwent pre-procurement…
2021 American Transplant Congress
Liver Dysfunction Following Lung Transplantation
E. J. Hyzny¹, E. G. Chan¹, J. P. Ryan¹, T. Harano¹, M. R. Morrell², P. G. Sanchez¹
¹Cardiothoracic Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA, ²Pulmonary, Allergy and Critical Care Medicine, University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To describe the incidence and risk factors for postoperative hepatic dysfunction (POHD) following lung transplantation (LT) and long-term outcomes for these patients.*Methods: We performed…
2021 American Transplant Congress
Hepatic Ferroptosis in Cold Stress and Warm Ischemia-reperfusion: A Novel Therapeutic Target in Liver Transplantation
H. Kojima¹, H. Hirao¹, K. Kadono¹, T. Ito¹, K. J. Dery¹, S. Kageyama², K. Nakamura³, F. M. Kaldas¹, D. G. Farmer¹, J. W. Kupiec-Weglinski¹
¹UCLA Medical Center, Los Angeles, CA, ²Kyoto University, Kyoto, Japan, ³Nishi-Kobe Medical Center, Kyoto, Japan
*Purpose: Ferroptosis, a newly discovered programmed cell death platform, due to iron-dependent accumulation of lipid peroxides, has been reported to aggravate ischemia-reperfusion (IR) injury in…
2021 American Transplant Congress
Incidence and Risk Factors for Nonmelanoma Skin Cancer in Lung Transplant Recipients
G. Holdren¹, E. Lushin¹, M. Duncan², C. Hage²
¹Pharmacy, Indiana University Health, Indianapolis, IN, ²Pulmonary Critical Care, Indiana University Health, Indianapolis, IN
*Purpose: The purpose of this study is to identify the incidence of nonmelanoma skin cancer (NMSC) post lung transplantation and to examine the relationship between…