2021 American Transplant Congress
Elexacaftor/ivacaftor/tezacaftor in Lung Transplant Recipients: A Case Series
1University of Chicago Medicine, Chicago, IL, 2Roosevelt University, Chicago, IL
*Purpose: Little data is published describing the safety or efficacy of elexacaftor/ivacaftor/tezacaftor in lung transplant recipients. Even though it is not expected to offer pulmonary…2021 American Transplant Congress
Lung Transplant Recipients Developing Early DSAs are Characterized by a Shift Towards Memory B Cells Directly After Transplantation
*Purpose: After lung transplantation (LTx), the development of early donor HLA-specific antibodies (eDSA) is associated with antibody-mediated rejection (AMR) and poor graft survival. Since 2013,…2021 American Transplant Congress
Textbook Outcome: A Novel Metric in Lung Transplantation Outcomes
*Purpose: Lung transplant programs are typically assessed based on 1-/3-year survival, however other factors such as quality of life, freedom from rejection and oxygen, etc.,…2021 American Transplant Congress
Use of Granulocyte Colony Stimulating Factor After Lung Transplantation is Not Associated with Increased Likelihood of Acute Cellular Rejection
*Purpose: The cause of neutropenia in lung transplant recipients is multifactorial, including medications, viral infections, and antecedent disease. Granulocyte colony-stimulating factor (G-CSF) is commonly used…2021 American Transplant Congress
Donor Lymphocytes in Peripheral Blood of Patients After Lung Transplantation Comprise High Frequencies of Killer Cell Immunoglobulin-like Receptor-positive T and NK Cell Subsets
*Purpose: For end-stage lung diseases, lung transplantation (LuTx) is the only curative treatment option. However, acute and chronic rejections are major limitations. Thus, a deeper…2021 American Transplant Congress
Acute Kidney Injury After Lung Transplantation: Incidence, Risk Factors and Outcomes. Results from a Monocentric Retrospective Cohort Study
*Purpose: Acute kidney Injury (AKI) occurs in more than 50% of patients after lung transplantation (LTx). Our purpose was to define incidence, risk factors and…2021 American Transplant Congress
Impact Analysis of Virtual Transplant Ambulatory Pharmacist During Covid-19
Massachusetts General Hospital, Boston, MA
*Purpose: During the COVID-19 pandemic, transplant centers were challenged to meet the demand for new telemedicine strategies. High-risk immunocompromised patients, such as lung transplant recipients…2021 American Transplant Congress
Donor T and NK Cells with a Special Tissue-Resident Memory Phenotype Migrate Into the Periphery of Lung Transplant Recipients – A Potential Feature for Tolerance Development
*Purpose: After lung transplantation (LuTx), a transient chimerism of donor cells exists in the blood of recipients due to the migration of lymphocytes from the…2021 American Transplant Congress
Lung Transplantation After Ex-Vivo Lung Perfusion versus Static Cold Storage: A Single Institution Cost Analysis
*Purpose: Ex-vivo lung perfusion (EVLP) allows for reconditioning of “marginal” lung grafts and extended lung preservation. However, EVLP is costlier than cold storage. We compared…2021 American Transplant Congress
Outcomes of IVIG Monotherapy for Donor-Specific Antibodies After Lung Transplantation
Vanderbilt University Medical Center, Nashville, TN
*Purpose: De novo donor-specific antibodies (DSA) are a risk factor for antibody mediated rejection (AMR) and poor clinical outcomes after lung transplant (LT). Intravenous immune…
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