ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver"

  • 2017 American Transplant Congress

    Prospective DSA Monitoring and Significance of De Novo DSA in Adult Liver Transplantation.

    S. Kubal,1 R. Mangus,1 J. Fridell,1 B. Ekser,1 R. Saxena,2 N. Rush,2 N. Higgins,4 M. Ghabril,3 M. Lacerda,3 A. Lobashevsky.4

    1Department of Surgery, Division of Transplantation, Indiana University School of Medicine, Indianapolis, IN; 2Department of Pathology, Indiana University School of Medicine, Indianapolis, IN; 3Department of Gastroenterology, Division of Hepatology, Indiana University School of Medicine, Indianapolis, IN; 4Department of Medicine, Immunology/Histocompatibility Laboratory, Indiana University School of Medicine, Indianapolis, IN

    Background: Post transplant course of circulating de novo donor specific antibodies (DSA) remains unknown after liver transplantation (LT).Methods: In a prospective study, sera from 92…
  • 2016 American Transplant Congress

    Barriers to the Wider Utilization of Living Donor Liver Transplantation (LDLT).

    A. Yegiants, E. Przybyszewski, A. Fox, J. Emond, B. Samstein.

    Center for Liver Disease and Transplantation, NewYork-Presbyterian Hospital/Columbia University Medical Center, New York, NY.

    Purpose: LDLT reduces waitlist mortality, improves access to transplantation and has post-transplant outcomes that are equivalent to or better than deceased donor transplant. Despite these…
  • 2016 American Transplant Congress

    Anti-Inflammatory Effects of AAV-Mediated TIMP-1 Gene Transfer in Hepatic Ischemia-Reperfusion Injury.

    S. Duarte, T. Fujii, G. Lipshutz, R. Busuttil, A. Coito.

    The Dumont-UCLA Transplant Center, Los Angeles.

    Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase1 (TIMP-1) is the…
  • 2016 American Transplant Congress

    Utility of a Routine Bench Cholangiogram for Deceased Split Liver Procedure.

    N. Battula, R. Anbarasan, V. Thumma, K. Sharif, T. Perera, P. Muiesan, D. Mirza.

    Liver Unit, Queen Elizabeth Hospital, Birmingham, United Kingdom; Liver Unit, Birmingham Children's Hospital, Birmingham, United Kingdom.

    Background: Biliary complications can result in a significant morbidity for split liver graft recipients. The segmental biliary anatomy, particularly the left biliary system is poorly…
  • 2016 American Transplant Congress

    Racial Disparities in Cognitive and Social Requirements Prior to Listing for Liver Transplant.

    M. Jesse, E. Goldstein, T. Macaulay, N. Rebhan, C.-X. Ho, M. Bebanic, L. Shkokani, M. Abouljoud, A. Eshelman, A. Yoshida.

    Transplant Institute, Henry Ford Health System, Detroit, MI.

    Guidelines for liver transplant candidates outline increased engagement of social supports in the context of patient cognitive impairments. However, there is little direction when limitations…
  • 2016 American Transplant Congress

    Activating Transcription Factor 5 (ATF5) Regulates Liver Ischemia/Reperfusion Injury.

    G.-Q. Shen,2 M. Morita,1 J. Fung,2 L. Lu,1,2 S. Qian.1,2

    1Immunology, LernerResearch Institute, Cleveland Clinic, Cleveland, OH; 2General Surgery, Transplant Center, Digestive Disease Institute, Cleveland Clinic, Cleveland, OH.

    Activating transcription factor 5 (ATF5), a member of the ATF/cAMP response element-binding proteins, is extremely highly expressed in the liver, the significance of which is…
  • 2016 American Transplant Congress

    Impact of Proximity MELD/PELD Points on Liver Redistricting Scenarios.

    S. Gentry,1,2 J. Pyke,1 D. Schladt,1 J. Zeglin,1 W. Kim,3 J. Lake,4 R. Hirose,5 D. Mulligan,6 A. Israni.1

    1Scientific Registry of Transplant Recipients, Minneapolis; 2United States Naval Academy, Annapolis; 3Stanford, Palo Alto; 4University of Minnesota, Minneapolis; 5Surgery, University of California, San Francisco; 6Surgery, Yale University, New Haven.

    Background: To address geographic disparity in liver allocation, a new organ distribution system consisting of 4 or 8 districts has been proposed (Gentry, Am J…
  • 2016 American Transplant Congress

    Racial Disparities in the Evaluation for Liver Transplantation.

    M. Jesse, E. Goldstein, N. Rebhan, C.-X. Ho, T. Macaulay, M. Bebanic, L. Shkokani, D. Moonka, M. Abouljoud, A. Yoshida.

    Transplant Institute, Henry Ford Health System, Detroit, MI.

    The majority of research on disparities in liver transplantation is on patients listed for transplant in the OPTN/UNOS database, not patients in the evaluation process…
  • 2016 American Transplant Congress

    Short-Term Starvation Attenuates Liver Ischemia Reperfusion Injury by SIRT1-Autophagy Signaling in Mice.

    J. Rao,1 H. Zhou,1 F. Zhang,1 X. Wang,1 Y. Zhai,2 L. Lu.1

    1Liver Transplantation Center, First Affiliated Hospital of Nanjing Medical University, Nanjing, China; 2Dumont-UCLA Transplant Center, David Geffen School of Medicine at University of California-Los Angeles, Los Angeles.

    Calorie restriction or starvation (fasting) has some beneficial effects on prolongation of life and increased resistance to stress. Calorie restriction has also been shown to…
  • 2016 American Transplant Congress

    Skipping Comparable Local Waitlist Candidates Under Share 35.

    E. Chow,1 A. Massie,1 X. Luo,1 C. Wickliffe,1 S. Gentry,2 A. Cameron,1 D. Segev.1

    1Surgery, Johns Hopkins University, Baltimore, MD; 2Mathematics, US Naval Academy, Annapolis, MD.

    Under Share-35, deceased donor (DD) livers are offered regionally to candidates with MELD≥35 before locally to lower MELD candidates. The characteristics and outcomes of local…
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