ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver"

  • 2017 American Transplant Congress

    Improved Preservation During Normothermic Ex-Vivo Liver Perfusion with Delta Opioid Agonist (D-Ala2, D-Leu5) Enkephalin (DADLE).

    E. Beal,1 J. Kim,1 D. Hayes Jr.,2 K. Washburn,1 B. Whitson,1 S. Black.1

    1Department of Surgery, Division of Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; 2Departments of Pediatrics and Internal Medicine, The Ohio State University Wexner Medical Center, Columbus, OH

    Background: The metabolic demand of donor livers during prolonged normothermic ex-vivo perfusion with its associated oxygen stress is a challenge. Delta opioid agonist (D-Ala2, D-Leu5)…
  • 2017 American Transplant Congress

    Use of Ledipasvir/Sofosbuvir with or without Ribavirin in Patients Post-Liver Transplant: Evaluation of Real-World Datasets.

    S. Flamm,1 M. Charlton,2 M. Manns,3 M. Prieto,4 I. Fernandez,5 M. Londono,6 R. Kwok,7 C. Smith,8 S. Lee,9 H. Ngo,9 A. Osinusi,9 A. Copans,9 L. Rossaro,9 M. Shoreibah,10 O. Massoud,10 M. Curry,11 M. Bourliere.12

    1Northwestern University, Chicago; 2Intermountain Medical Center, Murray; 3Hannover Medical School, Hannover, Germany; 4Hospital Universitari I Politecnic La Fe, Valencia, Spain; 5Hospital Universitario 12 de Octubre, Madrid, Spain; 6Servicio de Hepatología. Hospital Clinic, Barcelona, Spain; 7Walter Reed National Military Medical Center, DC; 8Medstar Georgetown University Hospital, Georgetown; 9Gilead Sciences, Inc., Foster City; 10University of Alabama Birmingham, Birmingham; 11Beth Israel Deaconess Medical Center, Boston; 12Hospital Saint Joseph, Marsielle, France

    PURPOSE: Post-liver transplant(LT) patients with HCV are considered a difficult-to-treat population. Ledipasvir/sofosbuvir(LDV/SOF) +ribavirin(RBV) for 12 weeks is approved in GT1 LT recipients based on the…
  • 2017 American Transplant Congress

    Protective Effect of Crepidiastrum denticulatum Extract Pretreatment Against Hepatic Ischemia-Reperfusion Injury in Mice.

    H. Jang, H. Lee, C. Park, D. Eom, J. Lee, M. Oh, J. Yoo, C. Rho.

    Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Anesthesia, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Pathology, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Surgery, University of Ulsan, Gangneung Asan Hospital, Gangneung, Gangwon, Korea; Natural Medicine Center, Korea Institute of Science and Technology, Gangneung, Gangwon, Korea; Natural Medicine Center, Korea Institute of Science and Technology, Gangneung, Gangwon, Korea

    Crepidiastrum denticulatum (CD) is a well-known, traditionally consumed vegetable in Korea, which was recently reported to have bioactive compounds with detoxification and antioxidant properties. Ischemia-reperfusion…
  • 2017 American Transplant Congress

    Ornithine Transcarbamylase Deficiency (OTC) in the Donor Liver, the Importance of Ascertaining the Cause of Death in the Brain Dead Donor.

    M. George,1 G. Thomas,1 A. Shun,1 M. Stormon.2

    1Paediatric Surgery and Transplant Surgery, Children's Hospital at Westmead, Sydney, NSW, Australia; 2Paediatric Gastroenterology, Children's Hospital at Westmead, Sydney, NSW, Australia

    The importance of ascertaining the cause of brain death in the donor is vital . We present a case of cadaveric liver donation (seg 2…
  • 2017 American Transplant Congress

    Restrictive Approach to Simultaneous Liver Kidney Transplantation.

    S. Sultan, S. Fitzpatrick, T. Kozlowski, S. Malik, S. Hanish, D. Bruno, M. Weir, W. Hutson, R. Barth, J. LaMattina.

    Surgery, University of Maryland School of Medicine, Baltimore

    Purpose: MELD based allocation and “Share 35” policy implementation has resulted in an overall increased incidence of renal failure at the time of liver transplantation,…
  • 2017 American Transplant Congress

    A Multi-Center Experience of Direct Acting Anti-Viral Agents in HCV Positive Patients Receiving HCV Positive Livers.

    N. Kapila,1 B. Zervos,2 B. Ismail,1 C. Lindenmeyer,3 V. Sanghi,3 K. Menon,3 G. Schnickel,2 J. Rivas,2 D. Reino,2 A. Tzakis.2

    1Gastroenterology, Cleveland Clinic, Weston, FL; 2Transplant, Cleveland Clinic, Weston, FL; 3Gastroenterology, Cleveland Clinic, Cleveland, OH

    Background: HCV cirrhosis is the leading indication for liver transplantation in the U.S. The development of direct acting anti-viral agents (DAAs) has changed the approach…
  • 2017 American Transplant Congress

    Chronic Hepatitis E-Genotype 3 Infection in Transplant Recipients: A Single Kidney and Pancreas Transplant Centre Experience.

    A. Kousios,1 R. Charif,1 E. Sanchez,2 S. Khan,3 F. Regan,4 S. Ijaz,5 D. Muir,2 B. Smith,3 R. Tedder,5 D. Taube,1 J. Galliford.1

    1Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom; 2Department of Infection and Immunity, Imperial College NHS Trust, London, United Kingdom; 3Department of Hepatology, Imperial College NHS Trust, London, United Kingdom; 4Department of Hematology, Imperial College NHS Trust, London, United Kingdom; 5Blood Borne Virus Unit, Virus Reference Department, MS-Colindale, Public Health England, London, United Kingdom

    Introduction:In the UK, Hepatitis E virus-genotype 3 (HEV3), is endemic and has now become the major cause of enterically transmitted viral hepatitis. Unlike HEV-genotype 1…
  • 2017 American Transplant Congress

    Infectious Complications Following Hepatectomy for Pediatric Hepatoblastoma.

    S. Commander, M. Kueht, T.-A. Ha, A. Rana, J. Goss, S. Vasudevan.

    Pediatric Surgery, Baylor College of Medicine, Houston, TX

    Purpose: To examine if patients with hepatoblastoma (HB) treated with both immunosuppression and chemotherapy have different rates of infection post-operatively than those treated with chemotherapy…
  • 2017 American Transplant Congress

    Prospective DSA Monitoring and Significance of De Novo DSA in Adult Liver Transplantation.

    S. Kubal,1 R. Mangus,1 J. Fridell,1 B. Ekser,1 R. Saxena,2 N. Rush,2 N. Higgins,4 M. Ghabril,3 M. Lacerda,3 A. Lobashevsky.4

    1Department of Surgery, Division of Transplantation, Indiana University School of Medicine, Indianapolis, IN; 2Department of Pathology, Indiana University School of Medicine, Indianapolis, IN; 3Department of Gastroenterology, Division of Hepatology, Indiana University School of Medicine, Indianapolis, IN; 4Department of Medicine, Immunology/Histocompatibility Laboratory, Indiana University School of Medicine, Indianapolis, IN

    Background: Post transplant course of circulating de novo donor specific antibodies (DSA) remains unknown after liver transplantation (LT).Methods: In a prospective study, sera from 92…
  • 2017 American Transplant Congress

    Liver Retransplantation: The Largest Post MELD Single Center Experience.

    F. Kaldas, I. Korayem, V. Agopian, T. Russell, S. Ebaid, A. Zarrinpar, H. Yersiz, D. Farmer, R. Busuttil.

    Surgery, University of California Los Angeles, Los Angeles, CA

    OBJECTIVE: Analyze post MELD liver retransplantation (Re-OLT) and identify recipient and donor preoperative risk factors associated with poor patient outcomes.BACKGROUND: Re-OLT is a high risk…
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