2017 American Transplant Congress
Evaluation of the Enhanced Recovery After Surgery Protocol in Living Liver Donors.
Background: Enhanced recovery after surgery protocol has proven its efficacy in many surgery fields in controlling pain and promoting early recovery . The implication of…2017 American Transplant Congress
AAV8 Delivery of TIMP-1 Prevents Hepatocyte Apoptosis After Liver Ischemia/Reperfusion Injury.
Dumont-UCLA Transplant Center, Los Angeles
Matrix metalloproteinase-9 (MMP-9) is a key mediator of leukocyte migration across vascular barriers in hepatic ischemia/reperfusion injury (IRI). Tissue inhibitor of metalloproteinase-1 (TIMP-1) is the…2017 American Transplant Congress
Disparity in Transplant Referral Patterns Based on Physician Dependent Variables.
Loyola University Medical Center, Maywood, Il
Introduction: Distance from a liver transplant (LT) center does not affect outcomes; however, rural areas have lower rates of listing and receiving solid organ transplants.…2017 American Transplant Congress
This is Why We Can't Have Nice Things- Real World Experience with Everolimus in Livers.
Purpose: To determine if discontinuation rates of everolimus (RAD) in clinical practice is higher than the 30% demonstrated in trials.Methods: This was a retrospective cohort…2017 American Transplant Congress
Hepatic Ischemia Reperfusion Injury After Liver Transplantation Is Associated with Acute Kidney Injury.
Background: The impact of liver allograft ischemia/reperfusion injury (IRI) on native renal function remains to be characterized. We hypothesized that severity of IRI correlates with…2017 American Transplant Congress
Effects of the Gut-Liver Axis on Ischemia-Mediated Hepatocellular Carcinoma Recurrence in the Mouse Liver.
Background: There is growing evidence that liver graft ischemia-reperfusion (I/R) is a risk factor for hepatocellular carcinoma (HCC) recurrence after liver transplantation, but the involved…2017 American Transplant Congress
Health Literacy, Functional Status and Transplant Eligibility Among Adult Liver Transplant Candidates.
University of Pennsylvania, Philadelphia; Northwestern University, Chicago
Introduction/Objectives: Low health literacy is associated with poor self-care in chronic diseases, however, is understudied in liver transplantation (LT). Study objectives were to evaluate associations…2017 American Transplant Congress
Graft-versus-Host Disease Following Deceased Donor Liver Transplant.
Henry Ford Hospital, Detroit, MI
We reviewed our institutional experience with graft-versus-host disease (GVHD) following orthotopic liver transplantation (OLT). All OLT from 10/1/2013-10/1/2016 were reviewed. Five cases of GVHD were…2017 American Transplant Congress
Factors Associated with Death or Transplant in Low-MELD Patients.
1Research, UNOS, Richmond, VA; 2Surgery, Mayo Clinic, Rochester, MN
Background. The Model for End-stage Liver Disease (MELD) score is a good discriminator of 3-month mortality in patients awaiting a liver transplant. Previous research showed…2017 American Transplant Congress
Histone Deacetylase Inhibition Mitigates Liver Ischemia/Reperfusion Injury in Mice.
Introduction: Ischemia/reperfusion injury (IRI) causes significant morbidity in liver transplantation and other surgical scenarios. A better understanding of the molecular mechanisms of IRI is required…
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