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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2020 American Transplant Congress

    Artificial Intelligence May Predicts Early Sepsis in Liver Transplantation

    R. D. Kamaleswaran1, R. Lowell Davis2, J. D. Eason3, S. Sataphaty4, V. R. Mas5, D. Maluf3

    1Biostatistics, Emory, Atlanta, GA, 2Center for Biomedical Informatics & Division of Critical Care Medicine, Department of Pediatrics, University of Tennessee Health Science Center, Memphis, TN, 3Department of Surgery, University of Tennessee Health Science Center, Memphis, TN, 4Sandra Atlas Bass Center for Liver Diseases & Transplantation, Northshore University Hospital/Northwell Health, NSHS, NY, 5Biostatistics, Emory, Atlanta, TN

    *Purpose: Sepsis post liver transplantation is a frequent challenge impacting patient outcomes. We aimed to develop an artificial intelligence method to predict earlier the onset…
  • 2020 American Transplant Congress

    Comparative Proteomics Analysis Identifies L-FABP as a Putative Biomarker of Graft Injury During Liver Transplantation Using the ITRAQ/MRM Approach

    M. Chen, Y. Zhang, M. Han, W. Ju, Q. Zhao, Y. Chen, D. Wang, X. He

    Transplant Center, First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China

    *Purpose: In liver transplantation, much of factors have a pernicious influence on liver donor quality, such as hepatic steatosis, long term of donor hypotension, cardiac…
  • 2020 American Transplant Congress

    Predicting the Safe Use of Deceased after Circulatory Death Liver Allografts in Primary Sclerosing Cholangitis

    V. Fleetwood, A. Gracon, D. Aufhauser, C. Papageorge, K. Janek, G. Leverson, D. Foley, J. Mezrich, A. D'Alessandro, L. Fernandez, D. Al-Adra

    Department of Transplantation, University of Wisconsin, Madison, WI

    *Purpose: The use of deceased after circulatory donation (DCD) liver allografts in patients with primary sclerosing cholangitis (PSC) is controversial given the already-increased risk of…
  • 2020 American Transplant Congress

    Transplanting Livers from Hepatitis C Virus Positive Donors; Is it Worth the Risk?

    J. W. Mensink1, B. Van Hoek2, B. Schaefer3, M. D. Van Rosmalen4, I. P. Alwayn5, A. E. Braat5

    1Leiden University Medical Center, Leiden, Netherlands, 2Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands, 3Dutch Transplant Foundation, Leiden, Netherlands, 4Eurotransplant International Foundation, Leiden, Netherlands, 5Transplant Surgery, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Before the introduction of Direct-Acting Antivirals (DAAs), only selected organs from Hepatitis C virus (HCV) positive donors were successfully transplanted into HCV positive recipients.…
  • 2020 American Transplant Congress

    Ikaros Regulates Macrophage Inflammation in Liver Ischemia-Reperfusion Injury: From Mouse-to-Human

    K. Kadono1, S. Kageyama1, K. Nakamura1, H. Hirao1, H. Kojima1, T. Ito1, K. J. Dery1, X. Li2, R. W. Busuttil1, F. Kaldas1, J. W. Kupiec-Weglinski1

    1Liver Transplant Surgery, UCLA, Los Angeles, CA, 2NIEHS, Durham, NC

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor for early allograft dysfunction and rejection episodes in liver transplantation (LT). The impact of Ikaros,…
  • 2020 American Transplant Congress

    Living Donor Liver Transplantation Should Be Considered Cautiously in Recurrent Hepatocellular Carcinoma within the Milan Criteria after Curative Liver Resection

    J. Kim1, N. Yi2, G. Choi1, C. D. Kwon3, K. Lee2, K. Suh2, J. Joh1

    1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 2Division of HBP Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, 3Department of Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH

    *Purpose: Insufficient data are available about patient survival following different treatments for recurrent hepatocellular carcinoma (HCC) after primary hepatectomy. We retrospectively evaluated the effects of…
  • 2020 American Transplant Congress

    Liver Transplantation for Patients with Cholangiocarcinoma: A Systematic Review and Meta-Analysis of Survival Rates

    I. A. Ziogas1, K. P. Economopoulos2, M. H. Hayat1, L. K. Matsuoka1, M. I. Montenovo1, M. Izzy1, S. P. Alexopoulos1

    1Vanderbilt University Medical Center, Nashville, TN, 2Duke University Medical Center, Durham, NC

    *Purpose: Liver transplant (LT) accompanied by neoadjuvant chemoradiation has emerged as the only curative option for unresectable cholangiocarcinoma (CCA). Although numerous centers have published their…
  • 2020 American Transplant Congress

    Humanized Mouse Reveals the Cytoprotective Function of Hepatocyte RXFP1 in Liver Transplant Recipients

    H. Kojima1, S. Kageyama1, K. Kadono1, H. Hirao1, K. J. Dery1, T. Ito1, G. Sugahara2, Y. Ishida2, T. Saito2, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1Surgery, The Dumont-UCLA Transplantation Center, Los Angeles, CA, 2Division of Gastrointestinal and Liver Disease, Keck School of Medicine, USC, Los Angeles, CA

    *Purpose: RXFP1 (RLX family peptide receptor 1) is a cognate receptor for relaxin (RLX), an insulin-like growth factor, with vasoactive/remodeling properties. We have documented cytoprotective…
  • 2020 American Transplant Congress

    Results of a Prospective Pilot Program for Transplantation of Patients with Alcohol-Related Liver Disease and Less Than 6 Months Abstinence

    J. Quance, L. Carrique, I. Sales, L. Lilly, M. Bhat, Z. Galvin, A. Tan, S. Abbey, J. Lynch, N. Selzner

    Multiorgan Transplant Institute, University of Toronto, Toronto, ON, Canada

    *Purpose: In Canada, 6 months of abstinence for those with alcohol-associated liver disease (ALD) is typically required prior to being listed for liver transplantation (LT).This…
  • 2020 American Transplant Congress

    Outcomes in Liver Transplantation with Use of Granulocyte-Colony Stimulating Factor

    K. Schnelle, A. Leino, M. Chunduru, L. Von Stein, O. Witkowsky

    The Ohio State Wexner Medical Center, Columbus, OH

    *Purpose: Questions remain if treatment with a granulocyte-colony stimulating factor (G-CSF) impacts clinical outcomes after liver transplant. The purpose of this study was to compare…
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