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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2020 American Transplant Congress

    Transplanting Livers from Hepatitis C Virus Positive Donors; Is it Worth the Risk?

    J. W. Mensink1, B. Van Hoek2, B. Schaefer3, M. D. Van Rosmalen4, I. P. Alwayn5, A. E. Braat5

    1Leiden University Medical Center, Leiden, Netherlands, 2Gastroenterology and Hepatology, Leiden University Medical Center, Leiden, Netherlands, 3Dutch Transplant Foundation, Leiden, Netherlands, 4Eurotransplant International Foundation, Leiden, Netherlands, 5Transplant Surgery, Leiden University Medical Center, Leiden, Netherlands

    *Purpose: Before the introduction of Direct-Acting Antivirals (DAAs), only selected organs from Hepatitis C virus (HCV) positive donors were successfully transplanted into HCV positive recipients.…
  • 2020 American Transplant Congress

    Ikaros Regulates Macrophage Inflammation in Liver Ischemia-Reperfusion Injury: From Mouse-to-Human

    K. Kadono1, S. Kageyama1, K. Nakamura1, H. Hirao1, H. Kojima1, T. Ito1, K. J. Dery1, X. Li2, R. W. Busuttil1, F. Kaldas1, J. W. Kupiec-Weglinski1

    1Liver Transplant Surgery, UCLA, Los Angeles, CA, 2NIEHS, Durham, NC

    *Purpose: Hepatic ischemia-reperfusion injury (IRI) represents a major risk factor for early allograft dysfunction and rejection episodes in liver transplantation (LT). The impact of Ikaros,…
  • 2020 American Transplant Congress

    Living Donor Liver Transplantation Should Be Considered Cautiously in Recurrent Hepatocellular Carcinoma within the Milan Criteria after Curative Liver Resection

    J. Kim1, N. Yi2, G. Choi1, C. D. Kwon3, K. Lee2, K. Suh2, J. Joh1

    1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea, Republic of, 2Division of HBP Surgery, Department of Surgery, Seoul National University College of Medicine, Seoul, Korea, Republic of, 3Department of Surgery, Digestive Disease and Surgery Institute, Cleveland Clinic, Cleveland, OH

    *Purpose: Insufficient data are available about patient survival following different treatments for recurrent hepatocellular carcinoma (HCC) after primary hepatectomy. We retrospectively evaluated the effects of…
  • 2020 American Transplant Congress

    Liver Transplantation for Patients with Cholangiocarcinoma: A Systematic Review and Meta-Analysis of Survival Rates

    I. A. Ziogas1, K. P. Economopoulos2, M. H. Hayat1, L. K. Matsuoka1, M. I. Montenovo1, M. Izzy1, S. P. Alexopoulos1

    1Vanderbilt University Medical Center, Nashville, TN, 2Duke University Medical Center, Durham, NC

    *Purpose: Liver transplant (LT) accompanied by neoadjuvant chemoradiation has emerged as the only curative option for unresectable cholangiocarcinoma (CCA). Although numerous centers have published their…
  • 2020 American Transplant Congress

    Humanized Mouse Reveals the Cytoprotective Function of Hepatocyte RXFP1 in Liver Transplant Recipients

    H. Kojima1, S. Kageyama1, K. Kadono1, H. Hirao1, K. J. Dery1, T. Ito1, G. Sugahara2, Y. Ishida2, T. Saito2, F. M. Kaldas1, R. W. Busuttil1, J. W. Kupiec-Weglinski1

    1Surgery, The Dumont-UCLA Transplantation Center, Los Angeles, CA, 2Division of Gastrointestinal and Liver Disease, Keck School of Medicine, USC, Los Angeles, CA

    *Purpose: RXFP1 (RLX family peptide receptor 1) is a cognate receptor for relaxin (RLX), an insulin-like growth factor, with vasoactive/remodeling properties. We have documented cytoprotective…
  • 2020 American Transplant Congress

    Results of a Prospective Pilot Program for Transplantation of Patients with Alcohol-Related Liver Disease and Less Than 6 Months Abstinence

    J. Quance, L. Carrique, I. Sales, L. Lilly, M. Bhat, Z. Galvin, A. Tan, S. Abbey, J. Lynch, N. Selzner

    Multiorgan Transplant Institute, University of Toronto, Toronto, ON, Canada

    *Purpose: In Canada, 6 months of abstinence for those with alcohol-associated liver disease (ALD) is typically required prior to being listed for liver transplantation (LT).This…
  • 2020 American Transplant Congress

    Outcomes in Liver Transplantation with Use of Granulocyte-Colony Stimulating Factor

    K. Schnelle, A. Leino, M. Chunduru, L. Von Stein, O. Witkowsky

    The Ohio State Wexner Medical Center, Columbus, OH

    *Purpose: Questions remain if treatment with a granulocyte-colony stimulating factor (G-CSF) impacts clinical outcomes after liver transplant. The purpose of this study was to compare…
  • 2020 American Transplant Congress

    Taking Liver Transplant to “The Friendly Skies”: A Novel Pilot Program Using Commercial Flights and Ride-Sharing Apps to Minimize Dry-Run Expenses and Expand Potential Donors

    G. J. McKenna, N. Onaca, H. Fernandez, E. Martinez, A. Gupta, A. Wall, J. Bayer, R. Ruiz, G. Testa

    Simmons Transplant Institute, Baylor University Medical Center, Dallas, TX

    *Purpose: Growth in liver transplantation means using marginal/DCD donors, however these often fail to yield a suitable organ. Organ procurement can require travelling significant distances,…
  • 2020 American Transplant Congress

    Multimodal Strategy for Hepatocellular Carcinoma in the Elderly: To Transplant or Not to Transplant

    M. Najjar1, O. Perez1, J. Zou1, S. Sun1, K. Bruestle1, P. Jiang1, E. Verna1, E. Zheng1, Y. Saenger1, A. Mathur1, A. Griesemer1, B. Samstein2, T. Kato1, K. Halazun2, J. Emond1

    1Columbia University Irving Medical Center, New York, NY, 2Weill Cornell Medicine, New York, NY

    *Purpose: Liver transplantation LT for HCC is curative but entails increased risk and is limited by organ scarcity. Alternative approaches such as locoregional therapy (LRT)…
  • 2020 American Transplant Congress

    Low Level CMV Detection and Effectiveness of Low Dose Valganciclovir Prophylaxis in Intermediate-Risk Liver Transplant Recipients

    A. Nolan1, B. Lovett2, B. Lindner1, J. G. Timpone3

    1Department of Pharmacy, Medstar Georgetown University Hospital, Washington, DC, 2Georgetown University School of Medicine, Washington, DC, 3Medstar Georgetown University Hospital, Washington, DC

    *Purpose: The purpose of this study is to assess the efficacy of low dose (450 mg/day) valganciclovir in preventing CMV infection in intermediate-risk liver transplant…
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