2015 American Transplant Congress
Hypothermic Machine Preservation Reduces Inflammatory, Hypoxic and Apoptotic Injuries in Human Liver Transplantation
Center for Liver Disease and Transplantation, Columbia University Medical Center, New York, NY.
Introduction: Hypothermic machine perfusion (HMP) is in its infancy in Liver Transplantation. We analyzed all molecular samples from our cumulative clinical experience at Columbia University.Methods:…2015 American Transplant Congress
Efficacy and Safety of Once-Daily Everolimus With Minimized Once-Daily Tacrolimus After Liver Transplantation
Background: The everolimus (EVR) pharmacokinetic profile allows for its once daily (OD) administration. We tested the efficacy and safety of a combination schedule of OD-EVR…2015 American Transplant Congress
Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities
Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…2015 American Transplant Congress
Renal Function Difference Between Anti-Hepatitis B Immunoglobulin(HBIG) Monotherapy and HBIG Combined With Entecavir in Liver Recipients
Background: To reduce the HBV reinfection after liver transplantation, anti-hepatitis B immunoglobulin (HBIG) alone or combination with antiviral nucleotide analogues are usually used regimen. However,…2015 American Transplant Congress
National Outcomes of Donation After Cardiac Death (DCD) Liver Transplantation Are Equivalent to Donation After Brain Death (DBD) Liver Transplantation Using Older (DBD) Donor Livers
University of Wisconsin, Madison, WI.
Background: Multiple studies have demonstrated that outcomes of DCD liver transplantation (LTx) are inferior to DBD LTx. Thus DCD liver transplantation represents only 7% of…2015 American Transplant Congress
Donor Hemodynamic Profile Presages Graft Survival in Donation After Cardiac Death Liver Transplantation
Transplant Institute, Georgetown University Hospital, Washington, DC.
IntroductionDonation after cardiac death (DCD) grafts are prone to periods of prolonged hypoxemia and hypotension prior to donor expiration, leading to an increased complication rate,…2015 American Transplant Congress
The Utility of Non-Invasive Intra Abdominal Pressure Monitoring After Pediatric Abdominal Organ Transplantation
Intra abdominal pressure (IAP) is monitored in critically ill children because intra-abdominal hypertension (IAH) may be associated with renal dysfunction and adverse outcomes.We retrospectively examined…2015 American Transplant Congress
Verification of OPTN Hepatocellular Carcinoma Recurrence Data
PURPOSE: OPTN data on HCC recurrence is increasingly utilized for a variety of studies; however, the accuracy of this data has not been examined. We…2015 American Transplant Congress
Early Allograft Dysfunction Causes Inferior Patient and Allograft Survival in Liver Transplantation; an Experience of 1952 Consecutive Liver Transplants
Transplantation, Mayo Clinic, Jacksonville, FL.
Background: Early allograft dysfunction (EAD) in liver transplantation (LT) is a useful intermediate outcome measure to predict graft loss or mortality. We sought to investigate…2015 American Transplant Congress
The Impact of the New Antivirals Sofosfuvir/Ledipasvir on Liver Transplantation for Hepatitis C Cirrhosis
The approval of potent antiviral therapy (AVT) with sofosfuvir/ledipasvir (sof/ldv) for hepatitis C (HCV) dramatically increased cure rates (SVR) to nearly 100%. A recent prospective…