ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2015 American Transplant Congress

    Sofosbuvir Therapy in Early and Late Post Liver Transplant Setting: A Single Center Experience

    X. Zervos,1 D. Beltran,2 B. Ismail,1 M. Watson,1 D. Sears,1 A. Tzakis.1

    1Liver Transplant, Cleveland Clinic Florida, Weston, FL; 2Pharmacy, Cleveland Clinic Florida, Weston, FL.

    Background: Hepatitis C (HCV) treatment has entered a new phase of excitement with new oral therapies. Here we describe our experience of sofosbuvir (SOF) based…
  • 2015 American Transplant Congress

    Incidence and Risk Factors for Infectious Complications in Liver Transplant Patients Converted to Everolimus

    A. Islam,1 J. DeVos,2 L. Teeter,3 E. Graviss,3 S. Gordon-Burroughs,1 A. Saharia,1 C. Mobley,1 A. Gaber,1 R. Ghobrial.1

    1Department of Surgery, Houston Methodist Hospital, Houston, TX; 2Department of Pharmacy, Houston Methodist Hospital, Houston, TX; 3Department of Pathology & Genomic Medicine, Houston Methodist Hospital, Houston, TX.

    AIM:Immunosuppression with an mTOR inhibitor plus calcineurin inhibitor (CNI) minimization is increasingly used in liver transplantation to protect against the nephrotoxic and neurotoxic side effects…
  • 2015 American Transplant Congress

    Renal Dysfunction After Liver Transplantation in Recipients With Pre-Transplant Normal Renal Function

    S. Lee,2 J. Lee,1 M. Kim,1 B. Kim,3 D. Joo,1 G. Choi,1 J. Choi,1 S. Kim.1

    1Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea; 2Surgery, Ajou University School of Medicine, Suwon, Republic of Korea; 3Internal Medicine, Yonsei University College of Medicine, Seoul, Republic of Korea.

    Background. Renal dysfunction is a severe complication associated with adverse outcomes after liver transplantation (LT). The aim of our study is to identify the incidence…
  • 2015 American Transplant Congress

    HLA Matching Affects Patient Survival, Graft Survival, and Incidence of Rejection Episodes in Largest Analysis to Date

    J. Weiner, Z. Cui, S. Mohan, E. Verna, A. Griesemer, J. Emond.

    Columbia Center for Liver Disease and Transplantation, New York Presbyterian-Columbia University Medical Center, New York, NY.

    Introduction: Though human leukocyte antigen (HLA) matching between donor and recipient affects both graft and patient survival after kidney and heart transplantation, prior analysis has…
  • 2015 American Transplant Congress

    Impact of Donor Post-Extubation O2 Delivery on Recipient Hypoxic Cholangiopathy in Donation After Circulatory Death Liver Transplantation: The University of Colorado Experience

    T. Chirichella,1 C. Dunham,2 M. Zimmerman,4 K. Conzen,1 S. Kelley,3 E. Phelan,1 T. Steinberg,1 T. Nydam,1 T. Bak,1 I. Kam,1 M. Wachs.1

    1Transplant Surgery, University of Colorado Hospital, Aurora, CO; 2Department of Surgery, St. Elizabeth Health Center, Youngstown, OH; 3Donor Alliance Organ Procurement Organization, Denver, CO; 4Transplant Surgery, Medical College of Wisconsin, Milwaukee, WI.

    The critical shortage of deceased organ donors has led to increased utilization of DCD liver grafts. The purpose of this study was to evaluate DCD…
  • 2015 American Transplant Congress

    Ischemia Reperfusion Injury in Orthotopic Liver Transplantation Primes the Adaptive Immune Response and Generation of Proinflammatory Cytokines

    A. Zarrinpar,1 P. Rao,2 C. Lassman,2 V. Agopian,1 F. Kaldas,1 D. Farmer,1 R. Busuttil,1 Y. Zhai,1 J. Kupiec-Weglinski,1 E. Reed.2

    1Surgery, University of California, Los Angeles, Los Angeles, CA; 2Pathology and Lab Medicine, University of California, Los Angeles, Los Angeles, CA.

    Background: Transplanted organs are exquisitely susceptible to effects of ischemia/reperfusion injury (IRI), an immune-mediated process that occurs during transplantation and beyond. Recipient and graft outcomes,…
  • 2015 American Transplant Congress

    Long-Term Survival Outcomes of Liver Transplantation for Klatskin Tumour: A Comparative Study With Radical Resection Surgery

    A. Hu, X. Zhu, X. He.

    Department of general Surgery, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong, China.

    Background and aim: Besides radical resection (RR), Liver transplantation (LT) is another suggested surgical modality for hilar cholangiocarcinoma (Klatskin tumour, KT) especially for patients whose…
  • 2015 American Transplant Congress

    Standardizing Quality Improvement Practices in Pediatric Liver Transplantation: The SPLIT A3 Project

    B. Kelly,1 R. Himes,2 J. Bucuvalas,3 L. Ware,1 S. Horslen.4

    1Surgery, Children's Hospital Pittsburgh, Pittsburgh, PA; 2Pediatrics, Texas Children's Hospital, Houston, TX; 3Pediatrics, Cincinnati Children's Hospital, Cincinnati, OH; 4Pediatrics, Seattle Children's Hospital, Seattle, WA; 5The Studies of Pediatric Liver Transplantation, EMMES Corporation, Maryland.

    Quality improvement (QI) programs are key drivers of continual reform in process and patient safety, but at present, there are no pediatric liver transplant (PLT)-specific…
  • 2015 American Transplant Congress

    Changes in Utilization, Discard, and Outcomes Associated With Hepatitis C (+) Donor Livers in the Era of Direct Acting Anti-Retroviral Therapy

    M. Bowring, L. Kucirka, X. Luo, A. Massie, D. Segev, C. Durand.

    Johns Hopkins University, Baltimore, MD.

    While 45% of liver candidates are hepatitis C (HCV) (+) and might benefit from an HCV (+) donor liver, only 7.1% receive one, and HCV…
  • 2015 American Transplant Congress

    Everolimus and Early Calcineurin Inhibitor Withdrawal Is Associated With Superior Renal Function: 5-Year Follow-Up of the Randomized PROTECT Liver Transplantation Study

    M. Sterneck, G. Kaiser, N. Heyne, N. Richter, F. Rauchfuss, A. Pascher, P. Schemmer, L. Fischer, C. Klein, S. Nadalin, F. Lehner, U. Settmacher, D. Gotthardt, M. Loss, S. Ladenburger, P. Wimmer, M. Dworak, H. Schlitt.

    PROTECT Study Group, Novartis Pharma GmbH, Germany.

    Purpose: At the end of the 12-month (M) PROTECT core study (NCT00378014), de novo liver transplant recipients (LTxR) who switched from a calcineurin inhibitor (CNI)…
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