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American Transplant Congress abstracts

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Articles tagged "Liver transplantation"

  • 2015 American Transplant Congress

    Etanercept for Graft Versus Host Disease Following Liver Transplantation

    E. Ticehurst,1 E. Blumberg,1 F. Vyas,1 K. Olthoff,1 A. Shaked,1 S. Bruno,1 K. Butcavage,1 E. Knight,1 G. Smith,1 S. Gill.2

    1Penn Transplant Institute, Phila, PA; 2Hematology-Oncology, Dept of Medicine, Univ of Penn, Phila, PA.

    Purpose: Graft versus host disease (GVHD) is a devastating diagnosis and treatment options, such as antithymocyte globulin (ATG), have poor response rates. With a goal…
  • 2015 American Transplant Congress

    Alpha-Fetoprotein as a Modifier of Anatomic Criteria for Transplantation of HCC Patients

    A. Daoud,1,3 M. Ghobrial,1 L. Teeter,2 E. Graviss,2 E. Asham,1 S. Burroughs,1 A. Saharia,1 C. Mobley,1 S. Mogawer,3 A. Sholkamy,3 M. Elshazly,4 M. Boktour,1 A. Gaber.1

    1Transplant Center, Methodist Hospital, Houston, TX; 2Pathology and Genomic Medicine, Methodist Hospital, Houston, TX; 3Internal Medicine Department, Cairo University Medical school, Cairo, Egypt; 4Surgery Department, Cairo University Medical school, Cairo, Egypt.

    Background:The current listing criteria (Milan, UCSF) for Orthotropic Liver Transplants (OLT) in hepatocellular carcinoma (HCC) patients emphasize the anatomic features of the tumor such as…
  • 2015 American Transplant Congress

    The Impact of Critical Illness and Pre-Transplant Hospitalization on Cost of Liver Transplantation

    S. Knechtle, L. Brummett, S. Perez.

    Surgery, Emory University School of Medicine, Atlanta, GA.

    In order to understand the cost impact of hospitalization and ICU admission immediately prior to liver transplantation (LT), we obtained all hospital costs associated with…
  • 2015 American Transplant Congress

    Liver Transplantation for Children With Autoimmune Hepatitis and Primary Sclerosing Cholangitis: An Analysis of the UNOS Database

    J. Jossen,1 R. Annunziato,2 J. Chu,1 H.-S. Kim,2 S. Sheflin,1 J. Lai,1 R. Arnon.1

    1Department of Pediatrics, Mount Sinai Medical Center, New York, NY; 2Fordham University, New York.

    Autoimmune hepatitis (AIH) and primary sclerosing cholangitis (PSC) are progressive immune-mediated inflammatory diseases that may require liver transplant (LT). Outcomes in children undergoing LT for…
  • 2015 American Transplant Congress

    Epidemiology of Pneumonia in a Cohort of 5,000+ Abdominal Solid Organ Transplant Recipients

    A. Masica, S. Delcroix-Lopes, M. Kouznetsova, C. Spak.

    Baylor Scott & White Health, Dallas, TX.

    Study purposeWe evaluated the epidemiology of pneumonia (PNE) in a longitudinal cohort of patients with abdominal (kidney, liver, and/or pancreas) solid organ transplants (SOT).MethodsRetrospective study…
  • 2015 American Transplant Congress

    Refinement of Non-Invasive Diagnostic Criteria to Differentiate Tumor from Bland Portal Vein Thrombosis Before Liver Transplant in Patients With Hepatocellular Carcinoma

    C. Sherman, S. Behr, J. Dodge, J. Roberts, F. Yao, N. Mehta.

    University of California San Francisco, San Francisco, CA.

    Differentiating tumor vs bland portal vein thrombosis (PVT) is essential in determining liver transplant (LT) candidacy for patients with hepatocellular carcinoma (HCC). The primary aim…
  • 2015 American Transplant Congress

    Small RNA Sequencing-Enabled Discovery of Circulating Extracellular MicroRNAs as Noninvasive Biomarkers of Liver Allograft Status

    H. Yang,1 T. Muthukumar,1 K. Akat,2 D. Briskin,2 T. Tuschl,2 M. Suthanthiran.1

    1Weill Cornell Medical Center, New York; 2Rockefeller University, New York.

    MicroRNAs are ideal candidates as blood-based biomarkers. Comprehensive profiling of microRNAs is challenging. We overcame the existing challenges by developing robust protocols for isolation of…
  • 2015 American Transplant Congress

    Outcomes of Hepatitis C Virus (HCV) Treatment Following Liver Transplantation in the Era of Direct-Acting Antiviral Medications

    S. Baggett,1 D. Jones,1 M. Shoreibah.2

    1Department of Pharmacy, UAB Hospital, Birmingham, AL; 2Department of Gastroenterology, UAB Hospital, Birmingham, AL.

    BACKGROUND: The treatment of HCV is one of the most rapidly changing areas of medical practice. These agents have been shown to be safe and…
  • 2015 American Transplant Congress

    Everolimus-Based Immunosuppression Is Associated With a Reduced Risk of New-Onset Malignancies After Liver Transplantation

    P. De Simone,1 P. Carrai,1 L. Coletti,1 D. Ghinolfi,1 D. Campani,2 F. Filipponi.1

    1Hepatobiliary Surgery and Liver Transplantation, University of Pisa Medical School Hospital, Pisa, Italy; 2Pathology, University of Pisa Medical School Hospital, Pisa, Italy.

    Background and aim: The inhibitor of the mammalian target of rapamycin (mTOR) everolimus (EVR) has shown anti-proliferative effects in experimental and clinical models. We investigated…
  • 2015 American Transplant Congress

    Risk of End-Stage Renal Disease After Living Donor Liver Transplantation: Overall Incidence and Comparisons to Deceased Donor Recipients

    D. Goldberg,1 R. Ruebner,2 P. Abt.3

    1Division of Gastroenterology, University of Pennsylvania, Philadelphia, PA; 2Division of Nephrology, Children's Hospital of Philadelphia, Philadelphia, PA; 3Department of Surgery, University of Pennsylvania, Philadelphia, PA.

    Introduction: Since initiation of MELD-based allocation for liver transplants, the risk of end-stage renal disease (ESRD) post-liver transplantation has increased. Recent US data demonstrated comparable,…
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