2017 American Transplant Congress
The Glasgow Prognostic Score and Its Variants Predict Mortality in Living Donor but Not in Deceased Donor Liver Transplantation for Hepatocellular Carcinoma: A Double-Center Validation Study.
The notion that inflammation parameters such as CRP and albumin might have an influence on outcome in malignant disease is gaining interest. Serum CRP- and…2017 American Transplant Congress
CD4 T Cell Depletion Mitigates Ischemic Hepatocellular Damage and Promotes Immune Regulation in Mouse Liver Allografts.
Background: Extended cold preservation contributes to organ ischemia-reperfusion injury (IRI), which stimulates host allo-reactivity, leading to inferior clinical outcomes. We have shown that CD4+ T…2017 American Transplant Congress
TIMP-3 Plays a Key Regulatory Role in the Cleavage of E-Cadherin and Has an Essential Protective Function in Hepatic IRI.
Surgery, David Geffen School of Medicine at UCLA, Los Angeles, CA
Liver ischemia-reperfusion injury (IRI) remains a challenging problem in clinical orthotopic liver transplantation. Tissue inhibitor of metalloproteinases-3 (TIMP-3), an extracellular matrix-associated protein, has been linked…2017 American Transplant Congress
Identifying Risk of Sepsis Early: A Way to Improve Outcomes for Patients with Early Allograft Dysfunction After Liver Transplantation?
General, Visceral and Transplantation Surgery, University Hospital Essen, Essen, Germany
Early Allograft Dysfunction (EAD) after Liver Transplantation (LT) is associated with increased morbidity and mortality, which is strongly associated with sepsis/septic shock. Aim of this…2017 American Transplant Congress
Inflammation, Impaired Energy Metabolism and Synthetic Failure Characterize the Liver Transcriptome of End-Stage Idiopathic Pediatric Acute Liver Failure (PALF).
Background: PALF requiring liver transplantation (LTx) often has no known etiology, and could result from undiagnosed metabolic disorders. Mitochondrial dysfunction is common in PALF, but…2017 American Transplant Congress
Disparity in Transplant Referral Patterns Based on Physician Dependent Variables.
Loyola University Medical Center, Maywood, Il
Introduction: Distance from a liver transplant (LT) center does not affect outcomes; however, rural areas have lower rates of listing and receiving solid organ transplants.…2017 American Transplant Congress
Donation After Cardiac Death (DCD) Liver Transplantation (LT) Is Not Associated with Post-LT Renal Dysfunction.
Transplant, Mayo Clinic, Jacksonville, FL
The relationship between DCD LT and post-LT renal dysfunction is unclear. Aim: Determine the effects of DCD LT compared to donation after brain death (DBD)…2017 American Transplant Congress
Simultaneous Liver-Kidney Transplants Using Donation After Cardiac Death Donors Long Term Outcomes Not Inferior to Brain Dead Donors.
University of Maryland School of Medicine, Baltimore, MD
Background:The Simultaneous use of both Liver and Kidney from the same DCD donor has become controversial with some authors advocating that DCD organs should not…2017 American Transplant Congress
Liver Transplantation Outcomes Using Anti-Thymocyte Globulin Induction in Patients with Autoimmune Hepatitis.
Transplantation Surgery, Virginia Commonwealth University, Richmond, VA
Background: The use of rabbit anti-thymocyte globulin (ATG) induction in high immunological risk patients with autoimmune hepatitis (AIH) could lower the rejection rates after liver…2017 American Transplant Congress
Predicting Immunologic Risk for Acute Rejection in Pediatric Liver Transplantation.
Yale University, New Haven, CT
Background: Studies in heart, lung, kidney, & liver transplantation (LT) indicate an increased negative impact of antibodies (Ab) to HLA on allograft outcome.Aim: To describe…
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