2016 American Transplant Congress
Transcatheter Aortic Valve Replacement (TAVR) for Severe Aortic Stenosis as a Bridge to Liver Transplantation.
Ochsner Medical Center, New Orleans, LA.
Background: Historically, severe symptomatic aortic stenosis (AS) has been corrected surgically with aortic valve replacement. In patients with end stage liver disease (ESLD), cardiac surgery…2016 American Transplant Congress
The Therapeutic Potential of Human Liver-Derived Stem Cell Transplantation in a Cirrhotic Liver Rat Model.
Cirrhosis is a long-term consequence of chronic hepatic injury and there are no effective treatment methods. Previous studies suggested that MSCs may ameliorate fibrogenesis through…2016 American Transplant Congress
Is SVR Associated with Improved Hepatic Function in Hepatitis C Gen 1 Pts with Cirrhosis 1 Year After Completing Treatment with Sofosbuvir + Simeprevir +/- Ribavirin?
Background: Combination antiviral therapy involving Sofosbuvir (SOF) & Simeprevir (SIM) +/- Ribavirin (RBV) is a relatively safe & effective Tx option in pts with gen…2015 American Transplant Congress
High Tolerability With Sofosbuvir-Based Direct-Acting Antiviral Therapy in Liver Transplant Recipients With Recurrent Hepatitis C
Background: Reports on efficacy, safety, and tolerability of sofobuvir-based antiviral regimens in liver transplant recipients with recurrent hepatitis C are limited. Methods: We performed a…2015 American Transplant Congress
Hospital Characteristics Mediate Variation in Cirrhosis Mortality in Transplant and Non-Transplant Facilities
Hospitals vary significantly in cirrhosis mortality. We aimed to determine whether hospital structural characteristics mediate this effect.Methods: We used 2009 data from the HCUP Nationwide…2015 American Transplant Congress
Survival Benefit of Simultaneous Liver Kidney (SLK) Transplant in Liver Transplant Candidates With Renal Dysfunction
Survival benefit of SLK over liver transplant alone (LTA) in patients with same level of renal dysfunction and effect of organ quality on mortality are…2015 American Transplant Congress
Distal Splenorenal Shunt (DSRS): A Durable Bridge to Liver Transplantation
Transplantation and Hepatobiliary Diseases, Lahey Clinic Medical Center, Burlington, MA.
Background: Variceal bleeding has a high rate of in-hospital mortality approaching 50%. Patients with well-compensated cirrhosis and recurrent variceal bleeding may benefit from long-term prophylaxis…2015 American Transplant Congress
Unrecognized Synchronous Hepatocellcular Carcinoma Lesions in Explanted Liver Transplant Specimens
Introduction: Liver resection for early-stage hepatocellular carcinoma (HCC) is limited by high surgical risk in cirrhotics and high rates of intrahepatic recurrence. We postulated that…2015 American Transplant Congress
Estimation of Glomerular Filtration Rate With Serum Cystatin C Accurately Discriminates Renal Dysfunction in Liver Transplant Candidates With End-Stage Liver Disease
Background: Renal insufficiency is common in end-stage liver disease (ESLD) and is linked to survival in patients awaiting liver transplantation. Serum creatinine correlates poorly with…2015 American Transplant Congress
MELD Velocity An Early Predictor of Increased Mortality Risk
INTRODUCTION: MELD is a satisfactory predictor of 3-month mortality in patients with cirrhosis. However, sub-populations of patients at increased hazard of mortality, but not well…