2022 American Transplant Congress
A Single-Center Cross-Sectional Analysis of Lipid Management in Kidney Transplant Recipients: Is It Time to Reassess KDIGO Guidelines?
1Renal Division, Brigham and Women's Hospital, Boston, MA, 2Brigham and Women's Hospital, Boston, MA
*Purpose: Cardiovascular disease remains the leading cause of mortality after kidney transplant, accounting for more than 30% of total deaths. Dyslipidemia is common following transplantation,…2022 American Transplant Congress
Immunometabolism of Regulatory T Cells Enhanced by Lipid Nanoparticles
*Purpose: Human regulatory T cell (Treg) metabolism is highly dependent upon a number of factors, including cholesterol obtained from circulating lipoproteins. We have developed high-density…2022 American Transplant Congress
A Nationwide, Multi-Center Survey of Lipid Management Strategies in Kidney Transplant Recipients
Renal division, Brigham and Women's Hospital, Boston, MA
*Purpose: KDIGO 2013 guidelines for the management of lipid transplant recommend the use of statins in all kidney transplant recipients (KTRs), but with weak evidence…2020 American Transplant Congress
De Novo NAFLD Post-Liver Transplant is Defined by Altered Lipid Metabolism and Mitochondrial Dysfunction
*Purpose: De Novo Non-alcoholic Fatty Liver Disease (NAFLD) affects up to 35% of liver transplant (LT) recipients transplanted for non-NAFLD indications. Non-alcoholic steatohepatitis (NASH), the…2020 American Transplant Congress
Free Fatty Acids and Delayed Graft Function after Kidney Transplantation: A Single Center Analysis
*Purpose: Delayed graft function (DGF) is one of the most common obstacles of donation after circulatory death (DCD) kidney transplantation. Serum free fatty acids (FFAs)…2020 American Transplant Congress
Undernutrition and Hypoleptinemia Modulate Cytomegalovirus Infection
1Pediatrics, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC
*Purpose: Cytomegalovirus (CMV) viremia/infection remains a significant cause of morbidity in transplantation, especially in the undernourished population. Undernutrition and hypoleptinemia have been implicated in other…2019 American Transplant Congress
Metabolic Profiling of Steatotic Human Livers during Ex-Vivo Normothermic Machine Perfusion
*Purpose: Nearly 40-60% of discarded livers are due to steatosis because of poor recovery from ischemia-reperfusion injury and compromised post-transplant function. We evaluated steatotic (ST)…2019 American Transplant Congress
Transplant Provider Adherence to Cardiovascular Disease Primary Prevention Guidelines in Liver Transplant Recipients
*Purpose: Blood pressure (BP) control, aspirin, and statin use are modifiable risk factors for primary prevention of atherosclerotic cardiovascular disease (ASCVD), stroke, and heart failure…2019 American Transplant Congress
Hypoadiponectinemia is Associated with Low Handgrip Strength in Renal Transplant Recipients
*Purpose: Adiponectin was synthesized and expressed by adipocytes. However, recently it was suggested that adiponectin is also secreted and expressed by skeletal muscle. Decline of…2019 American Transplant Congress
Serum Apolipoproteins B and A1 Predict the Development of Late Post-Transplant Diabetes Mellitus in Prevalent Adult Kidney Transplant Recipients
St Michael's Hospital, University of Toronto, Toronto, ON, Canada
*Purpose: Post-transplant diabetes mellitus (PTDM) increases adverse outcomes. The risk factors for PTDM have not been fully delineated. Glucose metabolism links closely to cholesterol metabolism.…
American Transplant Congress abstracts