Articles tagged "Kidney"

2016 American Transplant Congress
Learning Curve of Laparoscopic Donor Nephrectomy for Abdominal Transplant Surgery Fellows.
O. Serrano,¹ A. Bangdiwala,² D. Vock,³ V. Kirchner,¹ T. Dunn,¹ E. Finger,¹ T. Pruett,¹ A. Matas,¹ R. Kandaswamy.¹
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics, Masonic Cancer Center, Minneapolis, MN; ³Biostatistics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: Laparoscopic donor nephrectomy (LDN) requires a high degree of surgical competence and skill. UNOS recommends that fellowship-trained surgeons participate in 15 LDN to be…
2016 American Transplant Congress
Landscape of Hypertension Treatment in Former Kidney Donors.
L. Ferrara, O. Sanchez, D. Berglund, A. Matas, H. Ibrahim.
U of MN, Mpls.
The aim of this analysis is to describe the general epidemiological features for the development of hypertension and the most frequent medical therapies prescribed in…
2016 American Transplant Congress
Rapid Withdrawal of Donation After Cardiac Death Donors.
K. Mekeel,¹ J. Trageser,² W. Garrison,² J. Berumen,¹ L. Stocks,² A. Hemming.¹
¹Surgery, University of California-San Diego, La Jolla, CA; ²Lifesharing, San Diego, CA.
Purpose: Potential organ donors may be lost if procurement needs to occur emergently due to hemodynamic instability or family request, in particular if serologies and…
2016 American Transplant Congress
Reciprocal Effects of HDAC1 and HDAC2 Deletion on Renal Cold Ischemia Survival and Nuclear Co-Repressor Complex Expression.
D. Aufhauser Jr,¹ D. Murken,¹ Z. Wang,¹ A. Samanta,² G. Ge,¹ T. Bhatti,³ W. Hancock,^2,3 M. Levine.¹
¹Surgery, University of Pennsylvania, Philadelphia, PA; ²Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA; ³Pathology and Laboratory Medicine, The Children's Hospital of Philadelphia, Philadelphia, PA.
Introduction: Class I histone/protein deacetylases (HDACs) 1 and 2 bear >85% protein sequence homology and conventionally are thought to have similar function via occupancy in…
2016 American Transplant Congress
A Novel Intra-Abdominal Cooling System Prevents Graft Warming During Implantation for Robotic-Assisted Renal Transplantation.
R. Meier, M. Hagen, C. Joliat, J.-B. Buchs, A. Nastasi, R. Ruttimann, F. Lazeyras, P. Morel, L. Bühler.
Visceral and Transplant Surgery, Department of Surgery, Geneva University Hospitals and Medical School, Geneva, Switzerland, Geneva, Switzerland.
Background and objectiveRobotic kidney transplantation is minimal invasive and leads to decreased surgical site infection. In this stetting, warm ischemia time remains a valid concern.…
2016 American Transplant Congress
Distinct Phenotype and Function of Plasmacytoid Dendritic Cells from Kidney Allografts in Tolerant Recipients.
N. Oh,^1,2 C. Yang,^1,2,3 M. Tonsho,^1,2 D. Ndishabandi,^1,2,3 P. Russell,^1,2 R. Colvin,^1,3 J. Madsen,^1,2 A. Alessandrini.^1,2
¹Center for Transplantation Sciences, Massachusetts General Hospital, Boston, MA; ²Department of Surgery, Massachusetts General Hospital, Boston, MA; ³Department of Pathology, Massachusetts General Hospital, Boston, MA.
BACKGROUND: Cellular infiltrates in kidney allografts may be relevant to the induction or maintenance of regulatory tolerance. Here we examined the phenotype, anatomical distribution and…
2016 American Transplant Congress
Randomized Controlled Study Evaluating Adherence Monitoring with Electronic Feedback on Reducing Renal Allograft Rejection.
A. Bodzin, Y. Becker, M. Josephson, P. Witkowski, M. Lockwood, L. Potter, B. Kane, L. Lourenco, J. Millis.
Transplant Center, University of Chicago, Chicago, IL.
Purpose: The negative impact of non-adherence to the immunosuppressant medication (IM) regimen on transplant outcomes is well recognized. In an attempt to improve outcomes, the…
2016 American Transplant Congress
Outcomes of Donor Nephrectomy (DN) in the Obese.
O. Serrano,¹ A. Bangdiwala,² D. Vock,³ E. Minja,¹ W. Payne,¹ T. Dunn,¹ S. Chinnakotla,¹ E. Finger,¹ T. Pruett,¹ A. Matas,¹ R. Kandaswamy.¹
¹Surgery, Univ. of Minnesota, Minneapolis, MN; ²Biostatistics and Bioinformatics Core, Masonic Cancer Center, Minneapolis, MN; ³Biostatistics, Univ. of Minnesota, Minneapolis, MN.
PURPOSE: In an effort to address the critical organ shortage and rising obesity rates, the criteria for live kidney donation (LKD) have been expanded to…
2016 American Transplant Congress
A Randomized-Controlled Trial Comparing the Efficacy of CYP3A5 Genotype-Based with Bodyweight-Based Tacrolimus Dosing After Living Donor Kidney Transplantation.
N. Shuker,^1,2 R. Bouamar,² R. van Schaik,³ M. Clahsen -van Groningen,⁴ J. Damman,⁵ C. Baan,¹ J. van de Wetering,¹ A. Rowshani,¹ W. Weimar,¹ T. van Gelder,^1,2 D. Hesselink.¹
¹Internal Medicine, Erasmus Medical Centre, Rotterdam, Netherlands; ²Hospital Pharmacy, Erasmus Medical Centre, Rotterdam, Netherlands; ³Clinical Chemistry, Erasmus Medical Centre, Rotterdam, Netherlands; ⁴Pathology, Erasmus Medical Centre, Rotterdam, Netherlands; ⁵Pathology, Academic Medical Centre, Amsterdam, Amsterdam, Netherlands.
Patients expressing the cytochrome P450 (CYP) 3A5 gene require a higher tacrolimus dose to achieve therapeutic exposure compared with non-expressers. This randomized-controlled study investigated if…
2016 American Transplant Congress
Bioinformatic Analysis of Pathways Mediating Clusterin Functions in Kidney Cells Under Normoxia and Hypoxia.
G. Dairi, Q. Guan, C. Collins, C. Ong, M. Gleave, C. Nguan, C. Du.
Department of Urologic Sciences, University of British Columbia, Vancouver, BC, Canada.
Background: Clusterin (CLU) is a chaperone-like protein and contributes to the resistance of the kidney to ischemia-reperfusion injury (IRI), however its pathways are not fully…