Articles tagged "Kidney"

2021 American Transplant Congress
Impact of Pre-Screening on OPTN Kidney Paired Donation Pilot Program Transplant and Refusal Rates
S. E. Booker¹, R. Leishman¹, J. Musick¹, M. Oley¹, T. Sandholm², J. Dickerson³, M. Pavlakis⁴, V. Casingal⁵
¹UNOS, Richmond, VA, ²Carnegie Mellon University, Pittsburgh, PA, ³University of Maryland, College Park, MD, ⁴Beth Israel Deaconess Medical Center, Boston, MA, ⁵Carolinas Medical Center, Charlotte, NC
*Purpose: The OPTN Kidney Paired Donation Pilot Program (KPDPP) donor pre-screen tool allows centers to review and pre-accept or pre-refuse potential donors for individual candidates…
2021 American Transplant Congress
Attitudes Regarding Transplantation During the Pandemic: Give Me My Kidney Now!
T. Menser¹, M. Hobeika², A. Gaber², H. Ibrahim²
¹Houston Methodist Research Institute, Houston, TX, ²Houston Methodist Hospital, Houston, TX
*Purpose: The transplant community faces ongoing challenges regarding the conduct of organ transplantation during the COVID-19 pandemic, and patient treatment preferences during the pandemic require…
2020 American Transplant Congress
Quantifying the Number of ESRD Patients Who Might Benefit from Bariatric Surgery to Achieve Listing for Transplant
B. Orandi¹, P. MacLennan¹, S. Mehta¹, J. Grams¹, R. Stahl¹, R. Cannon¹, D. Anderson¹, M. Hanaway¹, C. Young¹, J. Purvis¹, N. Terrault², C. Lewis¹, J. Locke¹
¹University of Alabama at Birmingham, Birmingham, AL, ²University of Southern California, Los Angeles, CA
*Purpose: Mounting evidence suggests bariatric surgery may play a role in helping obese ESRD patients achieve sufficient weight loss to be transplant-eligible. We sought to…
2020 American Transplant Congress
Hematopoietic Cell Kinase Promotes Kidney Fibrosis Through Autophagy Pathway
C. Wei, L. Mou, K. Banu, M. Menon, W. Zhang, C. He, B. Murphy
Icahn School of Medicine at Mount Sinai, New York, NY
*Purpose: In our previous studies, we identified hematopoietic cell kinase (HCK) as a key driver of renal fibrosis through TGFβ/Smad3 pathway. Here in this study,…
2020 American Transplant Congress
Post- Transplant Recurrence of IgA Nephropathy: HLA as a Predictive Factor
C. R. Kavanagh¹, N. G. Jain¹, R. Vasilescu², J. Kamal³, I. Batal²
¹Pediatric Nephrology, Columbia University Medical Center, New York, NY, ²Pathology, Columbia University Medical Center, New York, NY, ³Surgery, Columbia University Medical Center, New York, NY
*Purpose: Genomic studies have identified several HLA antigens to be associated with IgA Nephropathy in the native kidney. In contrast to the native kidney, there…
2020 American Transplant Congress
Safety of Belatacept in HIV-Positive Kidney Transplant Recipients
K. El Sakhawi¹, A. Scemla², D. Bertrand³, C. Garrouste⁴, P. Malvezzi⁵, P. Grimbert¹, M. Matignon¹
¹Nephrology, APHP Henri Mondor, Créteil, France, ²Nephrology, APHP Necker Enfants Malades, Paris, France, ³Nephrology, CHU Bois Guillaume, Rouen, France, ⁴Nephrology, CHU Clermond Ferrand, Clermont Ferrand, France, ⁵Nephrology, CHU Grenoble, Grenoble, France
*Purpose: Kidney allograft survival in HIV-infected patients is lower than in the general population. Belatacept (instead of anticalcineurins (CNI)) has been shown to have a…
2020 American Transplant Congress
Identifying Factors Associated with Delayed Graft Function Severity Using the OPTN Database
K. Checchi¹, D. Stewart², A. Toll², J. Case¹, S. Kurian¹, C. Marsh¹
¹Scripps Health, La Jolla, CA, ²United Network for Organ Sharing Research Department, Richmond, VA
*Purpose: Delayed graft function (DGF) is a costly adverse outcome in kidney transplantation with negative implications for both graft and patient survival. Identifying factors associated…
2020 American Transplant Congress
Reverse Epidemiology and the Obesity Paradox for Patients with Chronic Kidney Disease
R. A. Choudhury¹, D. Yoeli¹, H. B. Moore¹, H. Yaffe¹, G. Hoeltzel², K. R. Dumon³, N. N. Williams³, P. L. Abt⁴, K. D. Conzen¹, T. L. Nydam¹
¹Department of Surgery- Division of Transplantation Surgery, University of Colorado Hospital, Aurora, CO, ²Thomas Jefferson University Hospital, Philadelphia, PA, ³University of Pennsylvania Hospital, Philadelphia, PA, ⁴Department of Surgery- Division of Transplantation Surgery, University of Pennsylvania Hospital, Philadelphia, PA
*Purpose: Obesity has been associated with both increased progression of chronic kidney disease as well as with a paradoxical improvement in survival among ESRD patients…
2020 American Transplant Congress
Does the Distance from the Transplant Center Impact Kidney Transplant (KT) DGF, CIT and Outcomes?
M. Laftavi¹, O. Pankewycz², R. Shahbazov¹, A. Almonte¹, B. Gallay², J. Leggat², R. Hod Dvorai¹, C. Hubbell¹, S. Narsipur²
¹Transplant, Upstate Medical University, SYRACUSE, NY, ²Nephrology, Upstate Medical University, SYRACUSE, NY
*Purpose: Currently, there is an ongoing debate regarding the efficient use of available organs (utility) versus the fair access to transplant (equity). UNOS is now…
2020 American Transplant Congress
Impact of a De Novo Belatacept Based Immunosuppressive Regimen on Kidney Transplant Outcomes
K. Joyal, T. Vanhove, B. Schreiber, M. Cote, S. Shao, N. Elias, H. Gilligan, K. Safa, E. Heher, W. Williams, C. Rogers
Massachusetts General Hospital Transplant Center, Boston, MA
*Purpose: Use of anti-thymocyte globulin (rabbit) (rATG) induction with belatacept/mycophenolate (MPA)/prednisone based immunosuppression (IS) has led to a reduction in rejection compared to that seen…