Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Significant Association of Vitamin-D Receptor (VDR) Gene Polymorphism and Incidence of De Novo DSA in Renal Transplantation.
L. Das, K. Ide, Y. Tanaka, N. Tanimine, S. Verma, H. Ohdan.
Department of Gastroenrological and Transplant Surgery, Hiroshima University, Hiroshima, Japan.
Objective-Renal Transplantation (RT) is the optimal choice forend stage renal disease. Despite all advances in the development ofeffective immunosuppressive regimens in renal transplantation one of…
2016 American Transplant Congress
Detecting Renal Allograft Inflammation Using Quantitative Urine Metabolomics and CXCL10.
J. Ho,¹ A. Sharma,² R. Mandal,³ D. Wishart,³ C. Wiebe,¹ L. Storsley,¹ M. Karpinski,¹ I. Gibson,⁴ P. Nickerson,¹ D. Rush.¹
¹Internal Medicine, University of Manitoba, Winnipeg, MB, Canada; ²Pediatrics & Child Health, University of Manitoba, Winnipeg, MB, Canada; ³Biological Sciences, University of Alberta, Edmonton, AB, Canada; ⁴Pathology, University of Manitoba, Winnipeg, MB, Canada.
Background. We studied urine metabolomics (UM) alone or combined with urine CXCL10 to non-invasively detect cellular infiltrates in renal allograft biopsies.Methods. Urines (n=137) were obtained…
2016 American Transplant Congress
Removing Geographic and Financial Barriers for Directed Living Kidney Donations: Lessons from Kidney Paired Donation.
M. Aeder,¹ R. Leishman,² D. Stewart.²
¹Univ Hosp Case Med Ctr, Cleveland, OH; ²UNOS, Richmond, VA.
Living donor (LD) kidney (K) transplants (Tx), which peaked at 6647 in 2004 (42.5% of tx), decreased by 2014 to 5538 (32.4% of tx). Although…
2016 American Transplant Congress
Pre-Transplant Cardiovascular Risk Factors Affect Kidney Allograft Survival: A Multi-Center Study in Korea.
J. An,^1,2 S. Ahn,³ E. Bae,² E. Kang,² H.-L. Kim,⁴ Y.-J. Kim,⁵ Y. Oh,^1,2 C. Lim,^1,2 Y. Kim,² Y. Kim,⁶ J. Lee.^1,2
¹Division of Nephrology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ²Division of Nephrology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ³Department of Preventive Medicine, Yonsei University Wonju College of Medicine, Wonju, Gangwon-do, Korea; ⁴Division of Cardiology, Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ⁵Division of Cardiology, Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ⁶Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Background - Pre- or post-transplant cardiovascular (CV) risk factors affect the development of CV events even after successful kidney transplantation (KT). However, the impact of…
2016 American Transplant Congress
Sequential Analysis of Donor-Specific Antibodies and Pathological Findings Using Intravenous Immunoglobulin in a Highly Sensitized Rat Kidney Transplant Model.
Y. Sawada,¹ K. Omoto,² N. Kohei,⁴ K. Kawanishi,³ M. Okumi,² H. Ishida,² T. Kazunari.²
¹Urology, Fukushima Rosai Hospital, Iwaki, Japan; ²Urology, Tokyo Women's Medical University, Tokyo, Japan; ³Pathology, Tokyo Women's Medical University, Tokyo, Japan; ⁴Urology, Shizuoka General Hospital, Shizuoka, Japan.
Intravenous immunoglobulin (IVIG) has evolved widespread use for treatment of acute antibody-mediated rejection (AAMR) and desensitization in highly HLA-sensitized patients. However, sequential change of the…
2016 American Transplant Congress
Transient Hepatitis B Core Positivity After Administration of IVIG for Desensitization (DES).
A. Nejad, A. Vo, J. Choi, S. Jordan.
Kidney Transplant, Cedars-Sinai Medical Center, LA, CA.
INTRODUCTION: IVIG has become an essential tool in the treatment of sensitized patients prior to solid organ transplantation and is routinely used to treat viral…
2016 American Transplant Congress
Age Gap Analysis Between Live Donor and Recipients in Kidney Transplantation: Opportunities to Improve Voluntary Exchange Programs and Kidney Paired Donation.
J. Rodriguez,¹ A. Patel,² M. Goggins.²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI; ²Transplant Institute, Henry Ford Hospital, Detroit, MI; ³Transplant Institute, Henry Ford Hospital, Detroit, MI.
Graft survival(GS) perception is that, with a smaller age gap between the donor(D) and recipient(R), better the outcome. It is unclear if there is an…
2016 American Transplant Congress
Transcriptome Profiles in Peripheral Blood of Kidney Graft Recipients.
J.-W. Seo,¹ H. Moon,¹ Y.-G. Kim,¹ K.-H. Jeong,¹ S.-J. Ihm,² J.-Y. Moon,¹ S.-H. Lee.¹
¹Division of Nephrology, Department of Internal Medicine, Kyung Hee University College of Medicine, Seoul, Republic of Korea; ²Department of Pathology, Kyung Hee University College of Medicine, Seoul, Republic of Korea.
The discovery of sensitive noninvasive diagnosis and the development of immune management in the renal allograft recipients are required for long-term graft survival. Although the…
2016 American Transplant Congress
A 30% Decrease in Post-kidney Transplant Estimated Glomerular Filtration Rate (eGFR) from 6 Mo-2 Y Is a Surrogate for 5 Y eGFR: Results from Clinical Trials in Organ Transplantation-(CTOT)-17.
G. Faddoul,¹ G. Nadkarni,¹ D. Hricik,² P. Heeger,¹ CTOT17 Investigators.
¹Medicine and Recanati Miller Transplant Institute, Icahn School of Medicine, NY, NY; ²Medicine, Case Medical Center, Cleveland, OH.
Predicting long-term kidney allograft outcomes using early clinical/biomarker data could guide individualized therapy. Emerging evidence in progressive native kidney disease indicates >30% decrease in eGFR…
2016 American Transplant Congress
Should Obese Patients Undergo Renal Transplantation? A Retrospective Analysis to Assess Whether Body Mass Index Can Affect Transplant Outcome.
A. Mehta,¹ A. Marriott,¹ A. Ghazanfar.²
¹St. George's, University of London, London, United Kingdom; ²Renal Transplant Unit, St. George's Hospital, London, United Kingdom.
This study aims to analyze our renal transplant recipient population in terms of perioperative complications (90 day) and graft survival (3 years) in relation to…