Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Angiotensin II Type 1 Receptor Antibodies Are Associated with Allograft Loss in Pediatric Renal Transplantation.
M. Pearl,¹ Q. Zhang,² M. Palma Diaz,³ J. Grotts,⁴ J. Brook,⁴ D. Gjertson,² P. Weng,¹ E. Reed,² E. Tsai.¹
¹Pediatrics, University of California-Los Angeles, Los Angeles, CA; ²Pathology and Laboratory Medicine, University of California-Los Angeles, Los Angeles, CA; ³Anatomic & Clinical Pathology, University of California-Los Angeles, Los Angeles, CA; ⁴Biostatistics, University of California-Los Angeles, Los Angeles, CA.
Background: Angiotensin II type 1 receptor antibody (AT1R-Ab) is associated with vascular injury and allograft failure in adult kidney transplantation. Its role in pediatric transplantation…
2016 American Transplant Congress
Pre-Transplant IgM to Post-Transplant IgG DSA Conversion May Be Affected by Immunosuppression.
A. Nguyen,¹ M. Everly,¹ L. Rebellato,² C. Haisch,² K. Briley,² P. Bolin,² S. Kendrick,² C. Morgan,² A. Maldonado,² P. Terasaki.¹
¹Terasaki Foundation Laboratory, Los Angeles, CA; ²East Carolina University, Greenville, NC.
Post-transplant (tx) IgG donor-specific antibodies (DSA), but not IgM DSA has been identified as one of the major causes of late graft loss. Considering the…
2016 American Transplant Congress
Induction Therapy with Depleting Antibodies in Low Immunological Risk Renal Transplant Patients Treated with a Steroid Free Regimen – Comparison of Alemtuzumab vs. Antithymocyte Globulin.
N. Bossini,¹ S. Sandrini,¹ R. Tardanico,² F. Valerio,¹ G. Setti,¹ C. Salviani,¹ S. Possenti,¹ P. Foini,¹ E. Marta,¹ G. Cancarini.¹
¹Division and Chair of Nephrology, A.O "Spedali Civili" and University, Brescia, Italy; ²Division and Chair of II Laboratory of Pathology, A.O "Spedali Civili" and University, Brescia, Italy.
Induction therapy with depleting antibodies reduces rejection rate and potentially improves efficacy of steroid free regimens after renal transplantation.This prospective, single-centre, cohort study evaluated cumulative…
2016 American Transplant Congress
Superior Waitlist and Equivalent Transplant Outcomes Among Hepatitis C RNA-Positive Patients Who Are Willing to Accept Hepatitis C Seropositive Kidneys.
J. Sageshima,¹ A. de Mattos,² C. Troppmann,¹ C. Santhanakrishnan,¹ J. McVicar,¹ B. Gallay,² M. Gandhi,² M. Alnimri,² R. Perez.¹
¹Surgery, University of California-Davis, Sacramento, CA; ²Internal Medicine, University of California-Davis, Sacramento, CA.
Background: kidney transplantation from hepatitis C seropositive (HCV+) donors may benefit hepatitis C RNA-positive (RNA+) candidates, but it is not clear how the acceptance/listing status…
2016 American Transplant Congress
Subtype-Compatible (A2/A2B–>B) Transplantation Under KAS Increases Access 3-Fold for Blood Type B Patients, yet Very Few Candidates Are Listed as Eligible.
D. Stewart,¹ W. Cherikh,¹ A. Kucheryavaya,¹ C. Bryan,² N. Turgeon,³ M. Aeder.⁴
¹UNOS, Richmond, VA; ²Midwest Transplant Network, Westwood, KS; ³Emory, Atlanta, GA; ⁴Univ Hosp Case Med Ctr, Cleveland, OH.
Background: Prior to the new kidney allocation system (KAS; 12/4/14), 8 OPOs participated in a voluntary policy variance permitting allocation of kidneys from subtype “A2”…
2016 American Transplant Congress
Early Steroid Withdrawal in African American Kidney Transplant Recipients: A Propensity Score Matching Analysis.
D. Taber, M. Gebregziabher, T. Srinivas, K. Chavin, P. Baliga, L. Egede.
MUSC, Charleston, SC.
Objective: The aim of this study was to assess the safety of steroid withdrawal in African American (AA) kidney transplant (KTX) recipients.Methods: Longitudinal cohort study…
2016 American Transplant Congress
Acute Operative Complications and 1,5,& 10 Year Outcomes in Living Donors by Type of Live Donor Nephrectomy – UK Cohort Study.
N. Krishnan,¹ L. Bradbury,² N. Raymond.¹
¹Renal & Transplantation, University Hospitals Coventry & Warwickshire NHS Trust, Coventry, United Kingdom; ²Statistics, National Health Service, Organ Donation & Transplant, Bristol, United Kingdom.
It is important to have a better understanding of the short and long term outcomes and risks of kidney donation. We studied the occurrence of…
2016 American Transplant Congress
Potential Kidney Donors with Asymptomatic Micorsocpic Hematuria: Histopathological Findings & Outcomes.
E. Hassan,^1,2 H. Aleid,¹ T. Zulfiquar,¹ I. Ibrahim,^1,3 H. Almana.⁴
¹Department of Kidney & Pancreas Transplantation, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia; ²Department of Nephrology, Fayoum University, Fayoum, Egypt; ³Department of Nephrology, Cairo University, Cairo, Egypt; ⁴Department of Anatomic Pathology, King Faisal Specialist Hospital & Research Center, Riyadh, Saudi Arabia.
Background: Microscopic hematuria is not uncommon in potential kidney donors. After excluding urological causes, most of these donors require kidney biopsy to exclude glomerular lesions.…
2016 American Transplant Congress
Elevated Intragraft Expression of Innate Immunity and Cell Death-Related Markers Characterizes Deceased Donor Conditions and Is a Risk Factor for Adverse Graft Outcome.
M. Eikmans,¹ J. Yang,¹ G. Haasnoot,¹ C. van Kooten,² M. Mallat,² H. de Fijter,² I. Bajema,³ F. Claas.¹
¹Immunohematology, LUMC, Leiden, Netherlands; ²Nephrology, LUMC, Leiden, Netherlands; ³Pathology, LUMC, Leiden, Netherlands.
Background: The innate immune response is increasingly being recognized in allograft injury after kidney transplantation. We aimed to establish the relationship of innate immune gene…
2016 American Transplant Congress
The Relationship Between Kidney Donor Profile Index and Six Month eGFR in Deceased Donor Recipients.
D. Keith, A. Nishio Lucar, G. Vranic.
Division of Nephrology, University of Virginia, Charlottesville, VA.
Kidney function, as measured by GFR, at 6 months post-kidney transplant is a powerful predictor of long-term post-transplant outcomes. This study sought to understand the…