Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Urinary Exosomal Annexin A1 Is a Predictive Biomarker of Post Kidney Transplant Complications.
H. Harada,¹ T. Murakami,² C. Yamamoto,² K. Hotta,¹ N. Fukuzawa,¹ M. Mitsuhashi.²
¹Kidney Transplant Surgery, Sapporo City General Hospital, Sapporo, Japan; ²Hitachi Chemical Co. America, Ltd., Irvine, CA; ³Nanosomix, Inc., Aliso Viejo, CA.
IntroductionMonitoring of kidney allograft condition is important. We had exhibited non-invasive diagnostic modality of post-kidney transplant complications using urine exosomal and microvesicule (EMV) mRNA of…
2016 American Transplant Congress
Cytokine Networks in Kidney Transplant Patients.
R. Sabat,¹ E. Witte,¹ P. Reinke,² K. Wolk,¹ N. Babel.^3,4
¹Interdisciplinary Group Molecular Immunopathology, and Psoriasis Research and Treatment Center, Dermatology/Medical Immunology, Charite University Medicine Berlin, Berlin, Germany; ²Department of Nephrology and Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany; ³Medical Clinic I, Marien Hospital Herne, University Clinic Ruhr-University Bochum, Herne, Germany; ⁴Berlin-Brandenburg Center for Regenerative Therapies, Charite University Medicine Berlin, Berlin, Germany.
As key mediators of the intercellular communication, cytokines play a crucial role in many processes following transplantation, including inflammation, tissue regeneration, and anti-microbial defense. Locally…
2016 American Transplant Congress
Renal Graft Survival According to Banff 2013 Diagnostic Categories in Indication Biopsies.
D. Redondo-Pachón,¹ C. Arias-Cabrales,¹ M. Pérez-Sáez,¹ J. Gimeno,² I. Sánchez-Güerri,² S. Bermejo,¹ A. Sierra,¹ C. Burballa,¹ M. Mir,¹ M. Crespo,¹ J. Pascual.¹
¹Nephrology, Hospital del Mar, Barcelona, Spain; ²Pathology, Hospital del Mar, Barcelona, Spain.
The impact of acute rejection in kidney graft survival is well known, but the prognosis of other diagnosis is uncertain. We evaluated the frequency and…
2016 American Transplant Congress
Gut Dysbiosis and Metabolic Disorders in Kidney Transplant Recipients.
M. Lecronier,¹ P. Tashk,¹ J. Aron-Wisnewsky,^2,3,4 E. Denamur,¹ O. Tenaillon,¹ B. Barrou,^4,5 J. Tourret.^1,4,5
¹IAME, UMR 1137, INSERM, Paris, France; ²Institute of Cardiometabolism and Nutrition, ICAN, Service de Nutrition, GH Pitié-Salpêtrière Charles Foix, AP-HP, Paris, France; ³UMR_S U1166, équipe NutriOmics, INSERM, Paris, France; ⁴Sorbonne Universités, Université Pierre et Marie Curie, Paris, France; ⁵AP-HP, Département d'Urologie, Néphrologie et Transplantation, GH Pitié-Salpêtrière Charles Foix, Paris, France.
IntroductionGut microbiota modifications (dysbiosis) have been observed in obese and/or diabetic patients. Kidney transplant recipients (KTR) are particularly exposed to the development of metabolic disorders,…
2016 American Transplant Congress
Watch Out for the Guy with the Low EPTS Score: Nonadherence and Kidney Allograft Failure.
A. Liu, K. Balabhadrapatruni, J. Augustine.
Medicine, University Hospitals Case Medical School, Cleveland, OH.
Background: Nonadherence is a known cause of rejection and kidney allograft failure. Our aim was to define risk factors for allograft loss related to nonadherence.…
2016 American Transplant Congress
Increasing Volume and Improved Survival in Solid Organ Transplantation for Amyloidosis – An Analysis of the UNOS Database.
J. Jaramillo,¹ J. Stehlik,¹ J. Fang,¹ R. Al-Dulaimi,¹ E. Gilbert,¹ S. Drakos,¹ O. Wever-Pinzon,¹ C. Selzman,¹ S. McKellar,¹ T. Kovacsovics,² J. Abraham,² M. Maurer,³ J. Nativi-Nicolau.¹
¹University of Utah, Salt Lake City, UT; ²Huntsman Cancer Institute, Salt Lake City, UT; ³New York-Presbyterian/Columbia University, New York, NY.
Background: Amyloidosis is a rare disease that results from accumulation of inappropriately folded proteins causing organ failure and poor prognosis. In the last decade several…
2016 American Transplant Congress
How Tacrolimus Variability Affects Donor Specific Antibodies, Rejection and Outcome After Kidney Transplantation.
S. Papachristos, A. John Velvet, A. Summers, A. Tavakoli, R. Dhanda, R. Pararajasingam, B. Forgacs.
Manchester Transplantation Unit, Manchester Royal Infirmary Central Manchester University Hospitals NHS Foundation Trust, Manchester, United Kingdom.
Purpose:To investigate the effect of tacrolimus(tac) variability on the development of Donor Specific Antibodies(DSA),rejection and outcome in relation to Age, Gender, Ethnicity and Body Mass…
2016 American Transplant Congress
Survival Benefit from Kidney Transplantation Using Kidneys from Deceased Donors Over 75 Years.
M. Pérez-Sáez,¹ E. Arcos,² J. Comas,² M. Crespo,¹ J. Lloveras,¹ J. Tort,² J. Pascual,¹ Catalan Renal Registry Committee.²
¹Nephrology, Hospital del Mar, Barcelona, Spain; ²Catalan Renal Registry, Organització Catalana de Trasplantaments, Barcelona, Spain.
Large registries have shown that end-stage renal disease patients have longer survival after kidney transplantation (KT) than remaining on dialysis. However, the outcome for kidneys…
2016 American Transplant Congress
15-Years Experience with the EUROTRANSPLANT Senior Program.
H.-M. Tautenhahn,¹ S. Brückner,¹ H.-M. Hau,¹ H. Morgül,¹ J. Broschewitz,¹ C. Pipiale,¹ F. Pankow,¹ S. Erler,² M. Bartels.¹
¹Universitätsklinikum Leipzig, Leipzig, Germany; ²Martin-Luther-Universität Halle, Halle, Germany.
Introduction: The ESP (Eurotransplant senior program), introduced in 1999 by EUROTRANSPLANT, is supposed to shorten the waiting period for elder recipients. The aim of this…
2016 American Transplant Congress
Incidence of Post-Transplant Lymphoproliferative Disorder in First, Kidney-Only Transplant Recipients Remains Stable.
J. Molony,¹ Y. Peng,¹ N. Baker,² U. Meier-Kriesche,³ J. Snyder.¹
¹Chronic Disease Research Group, Minneapolis; ²Brystol-Myers Squibb Company (BMS), Hopewell; ³BMS, Lawrenceville.
We estimated the incidence of and risk factors for post-transplant (TX) lymphoproliferative disorder (PTLD) in the 3 years post-TX for adults with first, kidney-only TX…