2016 American Transplant Congress
The Use of Sofosbuvir (SOF)-Containing Direct Antiviral Agents (DAA)-Based Regimens Requires Increase in Tacrolimus (Tac) Doses in Kidney Transplant (KT) Recipients with Hepatitis C Virus (HCV) Infection.
Background: The use of SOF-containing regimens based on NS5A inhibitors has not been shown interactions with Tac in liver transplant.Specific data on KT recipients are…2016 American Transplant Congress
Predictors of eGFR Slope at One Year in Kidney Transplants – A Big Data Approach.
Background: Estimated glomerular filtration rate (eGFR), a predictor of graft loss (GL) in kidney transplantation could inform intervention. National data yield eGFRs at fixed time…2016 American Transplant Congress
Impact of Pretransplant Non-Donor-Specific HLA Immunization: Mainly Class 1 Immunization Leads to Poor Immunologic Outcome and Graft Loss.
Nephrology, Charite, Berlin, Germany.
Background Anti-HLA immunization measured as Panel Reactive Antibodies (PRA) is known to have a negative impact on patient and graft survival. The influence of pre-transplant…2016 American Transplant Congress
Analysis of FSGS (Focal Segmental Glomerulosclerosis) Recurrence After Renal Transplantation.
Nephrology-Division, Hospital do Rim - UNIFESP, São Paulo, Brazil.
Purpose: To describe clinical-laboratorial profile and outcome of patients diagnosed with recurrent FSGS submitted to plasmapheresis.Methods: Retrospective single-center cohort study including all patients with recurrent…2016 American Transplant Congress
Fc Receptor Binding Assay for Functional Assessment of HLA Antibodies: Initial Clinical Validation.
Functional assessment of HLA antibodies (Abs) has historically been limited to complement-based assays, which have known limitations. Moreover, HLA Abs mediate injury by complement-independent mechanisms,…2016 American Transplant Congress
Malignancies Contribute to Presensitization with Alloreactive T-Cells in Kidney Transplant Recipients.
Alloreactive T-cells have been suggested to impact allograft outcome due to a higher incidence of acute rejection in the initial period after kidney transplantation. Knowledge…2016 American Transplant Congress
Delayed Graft Function (DGF) Does Not Accelerate Progression of Fibrosis During the First Year After Deceased Donor Kidney Transplantation.
BackgroundOur aim was to study the impact of DGF on the progression of interstitial fibrosis during the first post-transplant year.MethodsWe included all patients who received…2016 American Transplant Congress
Center Level Analysis of Changes in Living Donor Transplant Rates in the United States.
Medicine, Division of Nephrology, University of Virginia, Charlottesville, VA.
Rates of living donor kidney transplantation have been declining in the United States since 2003. Tremendous variation exists in the rate of living donor transplantation…2016 American Transplant Congress
Late Renal Xenograft Failure Is Antibody-Mediated: Description of the Longest-Reported Survival in Pig-to-Primate Renal Xenotransplantation.
Introduction. Xenotransplantation has the potential to alleviate the organ supply shortage, yet pig-to-primate renal xenotransplant has met limited success due to natural preformed anti-pig antibody.…2016 American Transplant Congress
Highly Sensitized Patients Transplanted via the Eurotransplant Acceptable Mismatch Program Have Excellent Long-Term Graft Survival.
Eurotransplant Reference Laboratory, Leiden University Medical Center, Leiden, Netherlands.
The Eurotransplant Acceptable Mismatch (AM) program has been initiated 25 years ago in order to enhance transplantation of highly sensitized renal transplant candidates. Instead of…
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