2016 American Transplant Congress
Circulating Angiotensin II Receptor: Possible Marker for Antibody Mediated Tissue Injury?
Transplant Surgery, VCU Health, Richmond, VA.
Background. Antibody mediated rejection is the leading cause of renal allograft failure. Membrane-bound angiotensin II receptor(AngII) in the renal allograft can be a target of…2016 American Transplant Congress
Polyclonal Treg Adoptive Therapy for Control of Subclinical Kidney Transplant Inflammation (TASK Pilot Trial).
Purpose: Early renal graft inflammation is associated with progressive fibrosis & late dysfunction. Treg therapy can reverse established inflammation in animal models. We conducted a…2016 American Transplant Congress
Short Term Changes in HRQOL Following Kidney Transplantation.
Health-Related Quality of Life (HRQOL) is a patient-centered outcome that measures the impact of a disease and its treatment. This is particularly relevant to those…2016 American Transplant Congress
Renal Outcome with Eculizumab in Patients with aHUS with Native and Transplanted Kidneys: Pooled Analysis of 100 Patients.
Purpose: aHUS often progresses to ESRD and requires transplant (tx). Eculiumab (ECU), a terminal complement inhibitor, inhibits TMA irrespective of tx status. We evaluated outcomes…2016 American Transplant Congress
De Novo Anti-HLA DSA Characteristics and Subclinical Antibody Mediated Kidney Allograft Injuries.
Nagoya daini red cross hospital, Nagoya, Japan.
Background It has been reported that de novo donor-specific HLA antibody (dn DSA) production is associated with chronic antibody-mediated rejection (CAMR) which leads to poor…2016 American Transplant Congress
A Non-Invasive Blood Transcriptional Assay, Ksort, Monitors Alloimmune Response in the Sailor Randomized Multicenter Trial.
Non-invasive diagnosis and prediction of acute rejection (AR) is a critical unmet need. A In a randomized multicenter trial of 222 renal transplant recipients a…2016 American Transplant Congress
A Kidney Paired Donation Standard Acquisition Charge Pilot Program.
1UT, Toledo; 2APKD, Perrysburg; 3Arbor Res, Ann Arbor.
Background/Purpose: A national non-profit Kidney Paired Dontion (KPD) organization undertook a demonstration project to redesign payment for KPD transplants with a payment model similar to…2016 American Transplant Congress
Recovery of eGFR in Both Donors and Recipients After Living Donor Kidney Transplantation.
MedStar Georgetown Transplant Institute, Washington, DC.
Purpose: LD kidney donation provides a much needed resource for patients with end stage renal disease. Providing adequate renal mass to the recipient (R) is…2016 American Transplant Congress
Pathogenic Role of Anti-HLA Antibodies on Endothelial Progenitor Cell Dysfunction of Highly Sensitized Kidney Transplanted Patients.
Anti-HLA antibodies (abs) bind to kidney graft endothelial cells inducing complement-mediated injury and humoral rejection. Endothelial Progenitor Cells (EPC) are bone marrow-derived precursors able to…2016 American Transplant Congress
A2 Kidneys into B Recipients: Is Postoperative Anti-A1 Titer Monitoring Useful?
Kidney and Pancreas Transplantation, Vanderbilt University Medical Center, Nashville, TN.
Background: Since the introduction of the new Kidney Allocation System in December 2014, our center implemented a protocol for transplanting A2 kidneys into B recipients…
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