Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Effect of mTOR Inhibitors on the Risk of Cancer Development After Kidney Transplantation in Chinese Population.
C.-C. Kao,¹ J.-S. Liu,² M.-H. Lin,² F.-C. Chang,¹ Y.-C. Lin,¹ H.-H. Chen,¹ T.-W. Chen,¹ C.-C. Hsu,² M.-S. Wu.¹
¹Department of Internal Medicine, Taipei Medical University Hospital, Taipei, Taiwan; ²Institute of Population Health Sciences, National Health Research Institutes, Zhunan, Taiwan.
Introduction The mTOR inhibitor is an immunosuppressive drug used in kidney transplantation. Whether the mTOR inhibitors is associated with reduced risk of cancer development in…
2016 American Transplant Congress
Smoking Exposure Among Kidney Allograft Recipients and Outcomes After Transplant.
H. Gillott,¹ S. Tahir,¹ F. Jackson-Spence,¹ F. Evison,² J. Nath,³ A. Sharif.³
¹Medical School, University of Birmingham, Birmingham, United Kingdom; ²Medical Informatics, Queen Elizabeth Hospital, Birmingham, United Kingdom; ³Nephrology and Transplantation, Queen Elizabeth Hospital, Birmingham, United Kingdom.
The causal effects of smoking on major comorbidity and mortality in the general population are well established. However, the influence of smoking exposure on kidney…
2016 American Transplant Congress
A 5-Year Multicenter Evaluation of Seasonal Influenza Infection in Transplant Recipients.
D. Kumar,¹ E. Cordero,⁴ E. Blumberg,² A. Limaye,⁵ M. Levi,⁷ L. Danziger-Isakov,⁹ J. Englund,⁸ S. Husain,¹ F. Silveira,¹⁰ G. Reid,⁶ T. Sharma,³ A. Humar.¹
¹UHN, Toronto, Canada; ²UPenn, Philadelphia; ³BCH, Boston; ⁴REIPI, Seville, Spain; ⁵UoWMC, Seattle; ⁶LUMC, Chicago; ⁷UCD, Denver; ⁸SCH, Seattle; ⁹CCHMC, Cincinnati; ¹⁰UPMC, Pittsburgh.
Background:Seasonal influenza infection may cause significant morbidity and mortality in transplant patients. However, there are limited prospective data on clinical presentations and determinants of outcomes.…
2016 American Transplant Congress
Comparison of C4d Deposition in Renal Biopsies with Luminex-Based C3d Single Antigen Bead (SAB) Detection.
R. Pelletier,¹ I. Balazs,² P. Adams,³ P. Steller,³ N. DiPaola,⁴ L. Rankin,³ A. Diez,⁵ M. Henry.¹
¹Surgery/Transplant, The Ohio State University Wexner Medical Center, Columbus, OH; ²Discovery Research, Immucor, Inc, Stamford, CT; ³Tissue Typing, The Ohio State University Wexner Medical Center, Columbus, OH; ⁴Methodist Hospital, Houston, TX; ⁵Nephrology, The Ohio State University Wexner Medical Center, Columbus, OH.
Recent interest in characterizing the complement-fixing ability of post-transplant donor specific alloantibodies (DSA) resulted in the enhancement of luminex solid phase alloantibody assays to determine…
2016 American Transplant Congress
Investigating Posttransplant Allo-Donor Specific CD57⁺ Cells in Patients with Alemtuzumab Induction and Belatacept-Based Regimen.
H. Xu, F. Feng, A. Kirk.
Department of Surgery, Duke University, Durham, NC.
Recent studies have showed correlation between CD4+CD57+PD1- cells and costimulation blockade resistant rejection (CoBRR) in patients treated with belatacept without depletional induction. We have recently…
2016 American Transplant Congress
Cognitive Impairment in Kidney Transplant Recipients.
A. Gupta,¹ D. Johnson,¹ G. Chen,¹ D. Subramaniam,¹ T. Polshak,¹ T. Thomas,¹ T. Schmitt,¹ D. Ladner,² A. Yu,¹ J. Burns.¹
¹University of Kansas Medical Center, Kansas City, KS; ²Northwestern University, Chicago, IL.
Background: Cognitive impairment is highly prevalent in end stage renal disease. The prevalence of cognitive impairment after kidney transplantation and the factors associated with it…
2016 American Transplant Congress
Non-Invasive – Minimalistic Approach Using Cell-Free MicroRNAs in Paired Plasma and Urine Samples for Early Diagnosis of Chronic Renal Allograft Dysfunction.
S. Bontha,¹ R. Gehrau,¹ E. Rhone,¹ A. King,² L. Gallon,³ K. Brayman,¹ D. Maluf,¹ V. Mas.¹
¹Surgery, UVA, Charlottesville, VA; ²VCU, Richmond; ³NWU, Chicago.
Background: Reducing use of tissue biopsy by efficiently using non-invasive samples for continuous monitoring and evaluation of graft function would be ideal. Reports indicate continuous…
2016 American Transplant Congress
Phenotype and Outcome of Antibody-Mediated Rejection Due to Pre-Existing and De Novo DSA in Kidney Recipients.
O. Aubert,¹ A. Loupy,¹ L. Hidalgo,² J. Reeve,³ D. Glotz,¹ C. Legendre,¹ C. Lefaucheur,¹ P. Halloran.³
¹Paris Research Center for Organ Transplantation, Paris, France; ²University of Alberta, Edmonton, Canada; ³ATAGC, Edmonton, Canada.
Antibody-mediated rejection (ABMR) presents with either pre-existing or de novo DSA. The aim of the study was to compare the two ABMR phenotypes and their…
2016 American Transplant Congress
mRNA Expression of BAFF and APRIL Receptors Increases in Acute Rejection in Kidney Transplant Recipients.
M. Minz,¹ R. Dhital,¹ R. Minz,² A. Sharma,¹ R. Nada,³ S. Singh,¹ D. Kenwar.¹
¹Renal Transplant Surgery, Post Graduate Institute of Medical Education and Research, Chandigarh, India; ²Immunopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India; ³Histopathology, Post Graduate Institute of Medical Education and Research, Chandigarh, India.
Introduction:BAFF and APRIL are known survival and growth of B- cells.BAFF and APRIL share two receptors i-TACI and ii- BCMA. Additionally, BAFF has strong affinity…
2016 American Transplant Congress
Analysis of Broken Chains in Kidney Paired Donation During an 8 Year Period within the National Kidney Registry.
N. Cowan,¹ J. Sinacore,² H. Gritsch,¹ J. Veale.¹
¹Department of Urology, University of California - Los Angeles Medical Center, Los Angeles, CA; ²National Kidney Registry, Babylon, NY.
Purpose: Chain transplantation in kidney paired donation (KPD) offers the ability to facilitate multiple kidney transplants between incompatible pairs using a non-directed donor (NDD) to…