Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Center-Level Variation in Association Between Early Hospital Readmission and Survival Following Kidney Transplantation.
S. Cramm, E. King, D. Segev.
Department of Surgery, Johns Hopkins, Baltimore.
Background: Early hospital readmission (EHR) following kidney transplantation (KT) is associated with inferior survival. However, incidence of EHR varies significantly across center following KT. Recent…
2016 American Transplant Congress
Tolerance Induction with Donor Bone Marrow Transplantation in Kidney Transplantation.
H. Park,¹ N. Lee,¹ S. Lee,¹ G. Choi,¹ C. Kwon,¹ S. Kim,¹ J.-W. Joh,¹ M. Kim,² Y. Kwon,² S.-K. Lee.¹
¹Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea; ²Transplantation Research Center, Samsung Biomedical Research Institute, Seoul, Republic of Korea.
Tolerance induction is considered to be a final goal in the field of organ transplantation. We have performed simultaneous bone marrow and kidney transplantation in…
2016 American Transplant Congress
NK-Activating MCMV Strain Is Associated with Increased Murine Renal Transplant Injury.
M. Shimamura,¹ M. Li,² B. Chen,² J. George,² T. Schoeb.³
¹Vaccines and Immunity, Pediatric Infectious Diseases, Nationwide Children's Hospital, The Ohio State University, Columbus, OH; ²Pediatric Infectious Diseases, Cardiothoracic Surgery, Nephrology, University of Alabama at Birmingham, Birmingham, AL; ³Pathology and Genetics, University of Alabama at Birmingham, Birmingham, AL.
Background: CMV contributes to inferior longterm kidney transplant survival. In a murine model, NK cells infiltrate MCMV infected renal allografts in greater numbers than in…
2016 American Transplant Congress
Have We Gone Too Far Defining Performance Outliers? One-Third of Kidney Transplant Programs Now Identified for Low Performance within Three Years.
J. Schold,¹ C. Miller,¹ M. Henry,² L. Buccini,¹ S. Flechner,¹ D. Goldfarb,¹ E. Poggio,¹ K. Andreonni.³
¹Cleveland Clinic, Cleveland, OH; ²Ohio State University, Columbus, OH; ³University of Florida, Gainesville, FL.
Transplant center report cards developed by SRTR are publicly available and utilized for regulatory oversight and insurance contracting. There are significant associations of performance oversight…
2016 American Transplant Congress
Serum Bicarbonate and Long-Term Outcomes in Kidney Transplant Recipients.
S. Park,¹ E. Kang,¹ M. Han,¹ J. Park,¹ S. Yang,² S. Park,³ I. Jung,⁴ C. Lim,⁵ Y. Kim,¹ Y. Kim,⁶ J. Lee.⁵
¹Department of Internal Medicine, Seoul National University College of Medicine, Seoul, Korea; ²Kidney Research Institute, Seoul National University College of Medicine, Seoul, Korea; ³Department of Internal Medicine, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea; ⁴Department of Surgery, Seoul National University Boramae Medical Center, Seoul, Korea; ⁵Department of Internal Medicine, Seoul National University Boramae Medical Center, Seoul, Korea; ⁶Department of Surgery, Asan Medical Center and University of Ulsan College of Medicine, Seoul, Korea.
Background: Metabolic acidosis indicated by low serum bicarbonate (TCO2) level has been known as a risk factor for mortality and progressive renal dysfunction in patients…
2016 American Transplant Congress
Utilization of HCV-Positive Donors' Kidneys: Potential Benefits in the Era of Direct Acting Antiviral (DAA) Therapy.
B. Amundsen,¹ M. Sise,² M. Lin,³ H. Deirawan,¹ E. Heher,² B. Kimball,¹ J. Markmann,¹ N. Elias.¹
¹Massachusetts General Hospital, Boston, MA; ²Massachusetts General Hospital, Boston, MA; ³Brigham and Women's Hospital, Boston, MA.
Organ shortage and expanding kidney waiting list fostered utilization of HCV positive donors' organs (HCVD+). HCVD+ kidneys have slightly worse long term outcomes compared with…
2016 American Transplant Congress
Impact of Machine Perfusion on Long-Term Kidney Transplant Outcomes.
S. Sandal,^1,2 X. Luo,² A. Massie,² M. Cantarovich,¹ D. Segev.²
¹MUHC, Montreal, Canada; ²JHU, Baltimore.
Machine perfusion (MP) has been shown to decrease DGF rates in kidney transplant (KT) recipients when compared with static cold storage (CS). However, there is…
2016 American Transplant Congress
Frailty in KT Recipients of All Ages.
M. McAdams-DeMarco, H. Ying, I. Olorundare, E. King, D. Segev.
Johns Hopkins, Baltimore.
Background: Among KT recipients, frailty increases the risk of DGF, early hospital readmission and mortality. While it is clear that frail KT recipients represent a…
2016 American Transplant Congress
Insights into the Treatment of Post-Transplant Focal Glomerulosclerosis: Experience Gained from a Concise Diagnostic and Management Protocol.
K. Koutroutsos,¹ R. Charif,¹ L. Moran,² J. Moss,² T. Cook,² C. Roufosse,² D. Taube,¹ M. Loucaidou.¹
¹Kidney and Transplant Centre, Imperial Healthcare NHS Trust, London, United Kingdom; ²Department of Histopathology, Imperial Healthcare NHS Trust, London, United Kingdom.
Background: Recurrence of Focal Glomerulosclerosis (FSGS) after kidney transplantation is associated with poor graft survival. We present results from a concise diagnostic and management protocol…
2016 American Transplant Congress
An Improved Method for the Evaluation of Microvascular Inflammation in Renal Allograft Biopsies.
M. Rooney,¹ Z. Ping,² D. Samarapungavan,³ R. Hennigar.⁴
¹Incyte Diagnostics, Spokane Valley, WA; ²Pathology, Beaumont Hospitals, Royal Oak, MI; ³Nephrology, Beaumont Hospitals, Royal Oak, MI; ⁴Nephropathology Associates, Little Rock, AR.
Background: Microvascular inflammation (MVI), assessed as glomerulitis (g) + peritubular capillaritis (ptc), is associated with T cell mediated (CMR) and antibody mediated (AMR) allograft rejection.…