Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Kidney Transplantation with Strong Preformed Donor-Specific Antibodies: Impact of C1q-Binding Ability.
J. Malheiro,¹ S. Tafulo,² S. Santos,¹ M. Costa,¹ L. Martins,¹ L. Dias,¹ A. Henriques.¹
¹Nephrology, CHP, Porto, Portugal; ²CSTP, Porto, Portugal.
HLA-incompatible kidney transplantation is associated with worse outcomes given the presence of donor-specific anti-HLA antibodies (DSA). Our aim was to investigate the association between preformed…
2016 American Transplant Congress
Rapid Detection of Acute Infection in Immunosuppressed Renal Patients with IRIDICA: A Pilot Study.
S. Hassan,¹ A. Adwaney,¹ A. Massiah,² R. Murphy,² S. Law,¹ S. Mohd-Afzal,¹ M. Wilks,² R. Thuraisingham.¹
¹Renal, Royal London Hospital, Barts Health Trust, London, United Kingdom; ²Microbiology, Barts Health Trust, London, United Kingdom.
BackgroundThe Abbott IRIDICA bacterial bloodstream (BAC BSI) assay is a rapid semi-quantitative diagnostic test that is able to detect over 800 significant pathogens using PCR…
2016 American Transplant Congress
Genomic-Derived Markers to Identify Calcineurin Inhibitor Nephrotoxicity in Pediatric Kidney Transplant Recipients.
E. Rhone,¹ R. Gehrau,² S. Bontha,² P. Walker,³ C. Dumur,⁴ D. Maluf,² V. Mas.²
¹Pediatrics, University of Virginia, Charlottesville, VA; ²Surgery, University of Virginia, Charlottesville, VA; ³Nephropath, Little Rock, AR; ⁴Pathology, Virginia Commonwealth University, Richmond, VA.
Background:Calcineurin inhibitor nephrotoxicity (CNIT) is a well-known contributor to chronic allograft dysfunction in kidney transplant recipients (KTRs). Pediatric KTRs are particularly at risk given their…
2016 American Transplant Congress
Acute Rejection, New-Onset Diabetes After Transplant and Transplant Outcomes in Pediatric Kidney Recipients: Analysis of the Organ Procurement and Transplant Network/United Network for Organ Sharing (OPTN/UNOS) Database.
A. Mehrnia, T. Le, T. Tamer, S. Bunnapradist.
Nephrology, UCLA, Los Angeles, CA.
Introduction Our objective was to identify the associations of new-onset diabetes after transplant (NODAT) and acute rejection (AR) in predicting patient mortality and transplant failure…
2016 American Transplant Congress
Impact of BKV Subtype Distribution on BKV Nephropathy, Viremia, and Renal Outcome in Patients After Renal Transplantation.
S. Anke,¹ L. Silvia,¹ H. Hermann,¹ H. Albert,² S. Corinna.²
¹Nephrology, Hannover Medical School, Hannover, Germany; ²Virology, Hannover Medical School, Hannover, Germany.
Factors determining the course of BK viral (BKV) infection remain uncertain. We studied the role of BKV subtype distribution in BKV-infected patients after renal transplantation.-We…
2016 American Transplant Congress
Standard Dose Valganciclovir Prophylaxis for High-Risk Kidney Transplant Recipients Reduces Incidences of Breakthrough and Resistant Cytomegalovirus Infection.
Y. Huang, J. Park, A. Naik, D. Kaul.
University of Michigan, Ann Arbor, MI.
Background: Valganciclovir (VGCV) 900 mg/day is the standard dose (SD) for CMV prophylaxis in patients with CrCl > 60 ml/min, although some transplant centers use…
2016 American Transplant Congress
The Burden and Outcomes of Fractures in Kidney Transplant Recipients.
N. Atagu, T. Nguyen, N. Phan, O. Famure, Y. Li, J. Kim.
Multi-Organ Transplant Program, Toronto General Hospital, University Health Network, Toronto, ON, Canada.
Background: Kidney transplantation confers an increased risk for bone fractures. However, there is poor consensus on the incidence of fractures in kidney transplant recipients (KTRs),…
2016 American Transplant Congress
Late Renal Allograft Rejection Is Predicted by High Intrapatient Variability of Tacrolimus Levels.
D. Goodall, M. Willicombe, A. McLean, D. Taube.
Imperial College Renal and Transplant Centre, Imperial College NHS Trust, London, United Kingdom.
IntroductionNonadherence to immunosuppressive medication is associated with rejection and graft loss. We have previously shown that intrapatient variability (IPV) of tacrolimus trough levels between 6-12…
2016 American Transplant Congress
Impact of the Kidney Allocation System with Deceased Donor Kidney Utilization at the DSA Level.
W. Ally,² C. Saunders,¹ K. Brayman,² A. Agarwal.²
¹Lifenet Health, Virginia Beach, VA; ²University of Virginia Health System, Charlottesville, VA.
Background: In December 2014, UNOS implemented broad sweeping changes in the new Kidney Allocation System (KAS). Recent summary reports by UNOS suggest that on a…
2016 American Transplant Congress
The Association of Life Expectancy by Resident Zip Code and Kidney Transplant Outcomes – What Is True Baseline Risk?
L. Buccini, D. Goldfarb, E. Poggio, S. Flechner, J. Schold.
Cleveland Clinic, Cleveland, OH.
Many factors beyond traditional clinical risk factors and demographics are associated with outcomes in the general population. These include behavioral, economic, genetic and environmental risks…