Articles tagged "Kidney transplantation"

2016 American Transplant Congress
The Effect of Everolimus and Tacrolimus Exposure Levels on Renal Histology Parameters 6 Months Post-Transplantation.
S. Yilmaz,¹ D. Shaffer,² Y. Qazi,³ K. McCague,⁴ D. Patel,⁴ V. Peddi,⁵ F. Vincenti.⁶
¹University of Calgary, Calgary, Canada; ²Vanderbilt University, Nashville; ³University of Southern California, Los Angeles; ⁴Novartis Pharmaceuticals Corporation, East Hanover; ⁵California Pacific Medical Center, San Francisco; ⁶University of California San Francisco, San Francisco.
We examined renal histology scores in patients with different exposure levels of everolimus (EVR) and tacrolimus (TAC) over 6 months.Renal transplant patients (N=613) were randomized…
2016 American Transplant Congress
Incidence, Risk Factors, and Outcomes of Delayed Graft Function in Deceased Donor Kidney Transplantation in a Brazilian Center.
A. Ribeiro,¹ M. Helfer,² O. Costa,² A. Viccari,¹ R. Manfro.^1,2
¹Division of Nephrology, Renal Transplant Unit, Hospital de Clinicas de Porto Alegre, Porto Alegre, Rio Grande do Sul, Brazil; ²School of Medicine, Federal University of Rio Grande do Sul, Porto Alegre, Rio Grande do Sul, Brazil.
Background. A high incidence of delayed graft function (DGF), after deceased donor kidney transplantation, occurs in Brazil and the reasons for such finding have not…
2016 American Transplant Congress
Kidney Survival Outcomes in Combined Intestinal-Kidney Transplant: An Analysis of the UNOS/OPTN Database 2000-2014.
A. Sharfuddin, T. Taber, M. Yaqub, I. Moinuddin, A. Khalil, O. Adebiyi, M. Mujtaba.
Medicine/Nephrology, Indiana University, Indianapolis.
Background: Intestinal transplants (isolated/modified/multi-visceral) carry a high morbidity and mortality. Kidney outcomes after combined intestinal (IT) with kidney transplant (CIKT) remain largely uninvestigated.Methods: The UNOS…
2016 American Transplant Congress
Survival Benefit of Kidney Transplantation in US Adults with Sickle Cell Nephropathy.
T. Purnell, X. Luo, S. Bae, A. Massie, D. Segev.
Johns Hopkins, Baltimore.
End-stage renal disease (ESRD) patients with sickle cell nephropathy (SCN) are less likely to receive a kidney transplant (KT) than ESRD patients without SCN. Comparing…
2016 American Transplant Congress
Everolimus and Low Dose Cyclosporine Immunosuppressive Regimen and Development of Anti HLA Donor Specific Antibodies.
E. Minetti,¹ L. Di Maria,¹ L. Caroti,¹ E. Buti,² P. Carta.¹
¹Nephrology unit, Careggi University Hospital, Florence, Italy; ²Nephrology Unit, Mayer Univerity Hospital, Florence, Italy.
Few data are available on the rate of de novo anti-HLA donor specific antibodies (DSA) with the use of everolimus in kidney transplant recipients.MaterialsWe selected…
2016 American Transplant Congress
The UK Kidney Donor Risk Index Score Predicts the Development of TRAS Post Deceased Donor Transplantation.
M. Willicombe, A. Baheerathan, S. Moser, A. McLean, M. Hammady, W. Gedroyc, D. Taube.
Imperial College Renal and Transplant Centre, Hammersmith Hospital, London, United Kingdom.
Introduction: Transplant renal artery stenosis (TRAS) is a heterogeneous disorder with different subtypes and aetiologies, which include traditional cardiovascular and transplant specific risk factors. Whether…
2016 American Transplant Congress
The Intrarenal Resistive Index Measured After Transplantation Is Determined by the Upstream Vascular System of the Recipient.
L. Heylen,¹ M. Naesens,¹ B. Sprangers,¹ S. Heye,² P. Verhamme,³ I. Jochmans,⁴ D. Monbaliu,⁴ J. Pirenne,⁴ D. Kuypers,¹ K. Claes.¹
¹Nephrology and Renal Transplantation, University Hospitals Leuven, Leuven, Belgium; ²Radiology, University Hospitals Leuven, Leuven, Belgium; ³Cardiovascular Medicine, University Hospitals Leuven, Leuven, Belgium; ⁴Abdominal Transplant Surgery, University Hospitals Leuven, Leuven, Belgium.
Objective: We recently demonstrated that the renal resistive index, measured after renal transplantation, reflects recipient characteristics, like recipient age and central hemodynamics, and not so…
2016 American Transplant Congress
Kidney Graft Homing of De Novo Donor Specific HLA Antibodies Is an Early Step within the Antibody-Mediated Graft Damage Process.
A. Nocera,¹ M. Cioni,² A. Tagliamacco,¹ A. Innocente,³ I. Fontana,⁴ A. Magnasco,² A. Nocco,³ A. Sementa,² G. Garibotto,¹ G. Ghiggeri,² M. Cardillo,³ P. Comoli,⁵ F. Ginevri.²
¹Transplant Immunology and Nephrology, University of Genova, Genova, Italy; ²Nephrology and Pathology, G. Gaslini Institute, Genova, Italy; ³Transplantation Immunology, Fondazione Cà Granda Ospedale Maggiore Policlinico, Milano, Italy; ⁴Kidney Transplant Surgery, IRCCS S.Martino-IST, Genova, Italy; ⁵Pediatric Hematology/Oncology, IRCCS Fondazione Policlinico S. Matteo, Pavia, Italy.
In this study, by a parallel analysis on sera and graft biopsies we have analyzed, in a pediatric cohort of unsensitized recipients of a first…
2016 American Transplant Congress
Alemtuzumab Induction Therapy in Elderly Kidney Transplant Recipients.
I. Yakubu,¹ B. Masters,¹ B. Ravichandran,¹ T. Sparkes,¹ M. Moss,¹ F. Rasetto,¹ S. Jonchhe,¹ B. Thomas,² N. Costa,² D. Leeser,² S. Bartlett,² A. Haririan.²
¹Pharmacy, University of Maryland Medical Center, Baltimore; ²University of Maryland Medical Center, Baltimore.
Background: In descriptive studies, alemtuzumab has been associated with an escalating risk of death and graft loss in elderly (≥65 years) kidney transplant recipients. However,…
2016 American Transplant Congress
Does Donor and Recipient Age Disparity Make a Difference with Expanded Criteria Donors?
M. Khan,¹ K. Jones,¹ H. El-Hennawy,¹ A. Farney,¹ J. Rogers,¹ G. Orlando,¹ A. Reeves-Daniel,² A. Palanisamy,² M. Gautreaux,³ S. Iskandar,³ W. Doares,⁴ S. Kaczmorski,⁴ R. Stratta.¹
¹Surgery, Wake Forest, Winston-Salem, NC; ²Internal Medicine, Wake Forest, Winston-Salem, NC; ³Pathology, Wake Forest, Winston-Salem, NC; ⁴Pharmacy, Wake Forest, Winston-Salem, NC.
The critical shortage of donor organs challenges the transplant community to optimize the use of organs from all consented deceased donors (DD). The purpose of…