Articles tagged "Kidney transplantation"

2016 American Transplant Congress
Sequential Analysis of Donor-Specific Antibodies and Pathological Findings Using Intravenous Immunoglobulin in a Highly Sensitized Rat Kidney Transplant Model.
Y. Sawada,¹ K. Omoto,² N. Kohei,⁴ K. Kawanishi,³ M. Okumi,² H. Ishida,² T. Kazunari.²
¹Urology, Fukushima Rosai Hospital, Iwaki, Japan; ²Urology, Tokyo Women's Medical University, Tokyo, Japan; ³Pathology, Tokyo Women's Medical University, Tokyo, Japan; ⁴Urology, Shizuoka General Hospital, Shizuoka, Japan.
Intravenous immunoglobulin (IVIG) has evolved widespread use for treatment of acute antibody-mediated rejection (AAMR) and desensitization in highly HLA-sensitized patients. However, sequential change of the…
2016 American Transplant Congress
Transient Hepatitis B Core Positivity After Administration of IVIG for Desensitization (DES).
A. Nejad, A. Vo, J. Choi, S. Jordan.
Kidney Transplant, Cedars-Sinai Medical Center, LA, CA.
INTRODUCTION: IVIG has become an essential tool in the treatment of sensitized patients prior to solid organ transplantation and is routinely used to treat viral…
2016 American Transplant Congress
Age Gap Analysis Between Live Donor and Recipients in Kidney Transplantation: Opportunities to Improve Voluntary Exchange Programs and Kidney Paired Donation.
J. Rodriguez,¹ A. Patel,² M. Goggins.²
¹Internal Medicine, Henry Ford Hospital, Detroit, MI; ²Transplant Institute, Henry Ford Hospital, Detroit, MI; ³Transplant Institute, Henry Ford Hospital, Detroit, MI.
Graft survival(GS) perception is that, with a smaller age gap between the donor(D) and recipient(R), better the outcome. It is unclear if there is an…
2016 American Transplant Congress
The Impact of Allograft Rejection on DNA Methylation After Kidney Transplantation.
K. Boer, E. de Wit, D. Hesselink, L. Hofland, M. Betjes, C. Baan.
ErasmusMC, University Medical Center Rotterdam, Rotterdam, Netherlands.
Introduction DNA methylation is a well-known epigenetic mechanism which plays a critical role in cell function by regulating gene expression. Variations in DNA methylation are…
2016 American Transplant Congress
Arteriolar Hyalinosis on Renal Transplant Protocol Biopsies Is Not Associated with Tacrolimus Exposure.
S. Yilmaz,¹ D. Shaffer,² Y. Qazi,³ F. Shihab,⁴ K. McCague,⁵ D. Patel,⁵ F. Vincenti.⁶
¹University of Calgary, Calgary, AB, Canada; ²Vanderbilt University, Nashville, TN; ³University of Southern California, Los Angeles, CA; ⁴University of Utah, Salt Lake City, UT; ⁵Novartis Pharmaceuticals Corporation, East Hanover, NJ; ⁶University of California San Francisco, San Francisco, CA.
Previous studies have implicated the development of arteriolar hyalinosis (AH) following kidney transplantation to chronic calcineurin inhibitor nephrotoxicity. Here, we examined the association between tacrolimus…
2016 American Transplant Congress
Association Between Pretransplant Body Mass Index and Outcomes in Patients Undergoing Living Kidney Transplantation: A Consideration of Gender Differences.
M. Okumi,¹ K. Unagami,¹ M. Furusawa,¹ T. Hirai,¹ Y. Okabe,² K. Masutani,³ T. Shimizu,¹ K. Omoto,⁴ H. Ishida,¹ T. Kitazono,³ K. Tanabe,¹ The Japan Academic Consortium of Kidney Transplantation (JACK).
¹Urology, Tokyo Women's Medical University, Tokyo, Japan; ²Surgery, Kyusyu University, Fukuoka, Japan; ³Medicine and Clinical Science, Kyusyu University, Fukuoka, Japan; ⁴Urology, Todachuo General Hospital, Saitama, Japan.
[lsaquo]Background[rsaquo]There is epidemiologic evidence of an association between elevated body mass index (BMI), the progression of cardiovascular disease (CVD), and end-stage renal disease (ESRD). For…
2016 American Transplant Congress
Impact of Social Support on Feelings of Powerlessness and Attitudes Towards the Kidney Transplant in Long-Term Inner City Recipients.
S. Wu, A. Brar, M. Markell.
Medicine, SUNY Downstate Medical Center, Brooklyn, NY.
Psychosocial factors play an important role in the post-transplant period, affecting adherence and quality of life. We investigated the relationships between social support, attitude towards…
2016 American Transplant Congress
Identifying Social Barriers to Health Literacy in ESRD Patients Undergoing Kidney Transplant Evaluation.
K. Leick,¹ J. Jones,¹ S. Witte,² L. Hunsicker,³ Z. Stewart.¹
¹Dept of Surgery, University of Iowa, Iowa City, IA; ²Dept of Social Work, University of Iowa, Iowa City, IA; ³Dept of Internal Medicine, University of Iowa, Iowa City, IA.
Background: Low health literacy is associated with increased hospitalizations and mortality. ESRD patients have reduced health literacy as ESRD disproportionately affects the elderly and individuals…
2016 American Transplant Congress
Evaluation According to Donor Source: 24-Month Results from Post-Hoc Analysis of the ELEVATE Study in Kidney Transplant Recipients.
J. de Fijter, H. Holdaas, P. Lopez, P. Bernhardt, D. Gaohong, J. Cruzado, M. van der Giet.
ELEVATE study group, Leiden, Netherlands.
Background: Several studies reported that recipients receiving renal allograft from living donors have better efficacy outcomes than the deceased donor counterparts. This post-hoc analysis of…
2016 American Transplant Congress
Renal Dysfunction at 12 Months Is Not Associated with Everolimus Exposure in De Novo Renal Transplant Recipients.
F. Shihab,¹ Y. Qazi,² S. Mulgaonkar,³ K. McCague,⁴ D. Patel,⁴ V. Peddi,⁵ D. Shaffer.⁶
¹University of Utah, Salt Lake City, UT; ²University of Southern California, Los Angeles, CA; ³Barnabas Health, West Orange, NJ; ⁴Novartis Pharmaceuticals Corporation, East Hanover, NJ; ⁵California Pacific Medical Center, San Francisco, CA; ⁶Vanderbilt University, Nashville, TN.
Renal dysfunction at 1 year post-transplantation is associated with poor graft outcome. Here, we assess post-transplant renal function associated with everolimus (EVR) and tacrolimus (TAC)…