ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2016 American Transplant Congress

    Tolerance Induction with Donor Bone Marrow Transplantation in Kidney Transplantation.

    H. Park,1 N. Lee,1 S. Lee,1 G. Choi,1 C. Kwon,1 S. Kim,1 J.-W. Joh,1 M. Kim,2 Y. Kwon,2 S.-K. Lee.1

    1Department of Surgery, Sungkyunkwan University School of Medicine, Samsung Medical Center, Seoul, Republic of Korea; 2Transplantation Research Center, Samsung Biomedical Research Institute, Seoul, Republic of Korea.

    Tolerance induction is considered to be a final goal in the field of organ transplantation. We have performed simultaneous bone marrow and kidney transplantation in…
  • 2016 American Transplant Congress

    Belatacept Does Not Inhibit Plasmablast Formation Supported by Follicular T Helper Cells, but Favors the Development of Transitional Regulatory B Cells in Kidney Transplant Patients.

    G. de Graav, D. Hesselink, M. Dieterich, R. Kraaijeveld, W. Weimar, C. Baan.

    Internal Medicine, Section Transplantation and Nephrology, Erasmus University Medical Center, Rotterdam, South Holland, Netherlands.

    Since the costimulatory inhibitor belatacept effectively blocks T-B cell interaction in animal transplant models, we studied the functional follicular T helper cells (TFH)-B cell interaction…
  • 2016 American Transplant Congress

    The Impact of Readmission following Kidney Transplantation: Is Readmission Becoming More Risky?

    E. King, L. Kucirka, M. McAdams-DeMarco, A. Massie, D. Segev.

    Surgery, Johns Hopkins University, School of Medicine, Baltimore, MD.

    BACKGROUND: Following kidney transplantation, 31% of recipients experience early hospital readmission (EHR) and readmission is independently associated with increased risk of graft loss and mortality.…
  • 2016 American Transplant Congress

    Treatments Against Renin-Angiotensin-Aldosterone System Could Influence FGF23 and Klotho Levels in Renal Transplant Recipients.

    S. Sezer,1 E. Tutal,1 Z. Bal,1 M. Uyar,1 M. Haberal.2

    1Nephrology, Baskent University Faculty of Medicine, Ankara, Turkey; 2General Surgery, Baskent University Faculty of Medicine, Ankara, Turkey.

    Purpose: Angiotensin-converting enzyme inhibitor ( ACEI) and angiotensin II receptor blocker (ARB) are frequently used in post transplant hypertension. Recent trials reported that renin-angiotensin-aldosterone system…
  • 2016 American Transplant Congress

    Efficacy and Safety of Direct Antiviral Agents (DAA)-Based Therapies for Hepatitis C Virus (HCV) Infection in Kidney Transplant (KT) Recipients.

    M. Fernandez Ruiz,1 A. García Santiago,2 N. Polanco Fernandez,2 R. Muñoz,3 A. Hernandez,2 E. González Monte,2 V. Mercado,2 I. Fernández,3 J. Aguado,1 M. Praga,2 A. Andrés.2

    1Unit of Infectious Diseases, Hospital Universitario “12 de Octubre”, Madrid, Spain; 2Nephrology, Hospital Universitario “12 de Octubre”, Madrid, Spain; 3Gastroenterology, Hospital Universitario “12 de Octubre”, Madrid, Spain.

    Background: The use of interferon-based regimens for HCV infection in KT recipients is limited due to the increased risk of acute graft rejection (AR), poor…
  • 2016 American Transplant Congress

    Predictors of eGFR Slope at One Year in Kidney Transplants – A Big Data Approach.

    J. Zhang, Z. Su, D. Taber, J. Marsden, W. Moran, P. Mauldin, T. Srinivas.

    MUSC, Charleston.

    Background: Estimated glomerular filtration rate (eGFR), a predictor of graft loss (GL) in kidney transplantation could inform intervention. National data yield eGFRs at fixed time…
  • 2016 American Transplant Congress

    Impact of Pretransplant Non-Donor-Specific HLA Immunization: Mainly Class 1 Immunization Leads to Poor Immunologic Outcome and Graft Loss.

    O. Staeck, F. Halleck, A. Staeck, L. Lehner, M. Duerr, E. Schrezenmeier, K. Budde, D. Khadzhynov.

    Nephrology, Charite, Berlin, Germany.

    Background Anti-HLA immunization measured as Panel Reactive Antibodies (PRA) is known to have a negative impact on patient and graft survival. The influence of pre-transplant…
  • 2016 American Transplant Congress

    Analysis of FSGS (Focal Segmental Glomerulosclerosis) Recurrence After Renal Transplantation.

    J. Mansur, G. Basso, M. Cristelli, G. Mata, T. Sandes-Freitas, G. Kirsztajn, H. Tedesco-Silva, J. Medina-Pestana.

    Nephrology-Division, Hospital do Rim - UNIFESP, São Paulo, Brazil.

    Purpose: To describe clinical-laboratorial profile and outcome of patients diagnosed with recurrent FSGS submitted to plasmapheresis.Methods: Retrospective single-center cohort study including all patients with recurrent…
  • 2016 American Transplant Congress

    Fc Receptor Binding Assay for Functional Assessment of HLA Antibodies: Initial Clinical Validation.

    E. Woodle, A. Girnita.

    U of Cincinnati, Cincinnati.

    Functional assessment of HLA antibodies (Abs) has historically been limited to complement-based assays, which have known limitations. Moreover, HLA Abs mediate injury by complement-independent mechanisms,…
  • 2016 American Transplant Congress

    Malignancies Contribute to Presensitization with Alloreactive T-Cells in Kidney Transplant Recipients.

    T. Schachtner,1,2 M. Stein,2 P. Reinke.1,2

    1Nephrology and Internal Intensive Care, Charite Campus Virchow Clinic, Berlin, Germany; 2Berlin-Brandenburg Center for Regenerative Therapies, Charite Campus Virchow Clinic, Berlin, Germany.

    Alloreactive T-cells have been suggested to impact allograft outcome due to a higher incidence of acute rejection in the initial period after kidney transplantation. Knowledge…
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