ATC Abstracts

American Transplant Congress abstracts

  • Home
  • Meetings Archive
    • 2020 American Transplant Congress
    • 2019 American Transplant Congress
    • 2018 American Transplant Congress
    • 2017 American Transplant Congress
    • 2016 American Transplant Congress
    • 2015 American Transplant Congress
    • 2013 American Transplant Congress
  • Keyword Index
  • Resources
    • 2016 Resources
      • 2016 Welcome Letter
      • ATC 2016 Program Planning Committees
      • ASTS Council 2015-2016
      • AST Board of Directors 2015-2016
    • 2015 Resources
      • 2015 Welcome Letter
      • ATC 2015 Program Planning Committees
      • ASTS Council 2014-2015
      • AST Board of Directors 2014-2015
      • 2015 Conference Schedule
  • Advanced Search

Analysis of Broken Chains in Kidney Paired Donation During an 8 Year Period within the National Kidney Registry.

N. Cowan,1 J. Sinacore,2 H. Gritsch,1 J. Veale.1

1Department of Urology, University of California - Los Angeles Medical Center, Los Angeles, CA
2National Kidney Registry, Babylon, NY.

Meeting: 2016 American Transplant Congress

Abstract number: 421

Keywords: Kidney transplantation

Session Information

Date: Tuesday, June 14, 2016

Session Name: Concurrent Session: Kidney Paired Exchange: Outcomes and Issues

Session Time: 2:30pm-4:00pm

 Presentation Time: 2:54pm-3:06pm

Location: Ballroom C

Related Abstracts
  • Matching Strategies in Kidney Paired Donation: A 7-Year Analysis of a Multi-Institutional Registry
  • Learning from Failures: A 7-Year Analysis of a Multi-Institutional Kidney Paired Donation Registry

Purpose: Chain transplantation in kidney paired donation (KPD) offers the ability to facilitate multiple kidney transplants between incompatible pairs using a non-directed donor (NDD) to initiate the sequence. Concerns regarding donors' ability to back out have been previously raised yet few data exist which evaluate the frequency of broken chains due to donor issues. The purpose of this study was to evaluate the rate and cause of broken chains within a large KPD program.

Methods: All patients undergoing renal transplantation through the NKR from 2008 through Sept 2015 were included for analysis. Broken chains were defined as chains in which a donor did not undergo donor nephrectomy despite their intended recipient having received a kidney. Real time swap failures were evaluated as a subset of broken chains and defined as a chain which was broken on the day of the planned surgery. Loops (closed KPD sequences not initiated by a NDD) were also analyzed. Descriptive statistical analysis was performed.

Results: A total of 281 chains and 76 loops were completed during the study period yielding a total of 1,483 transplants. 19 broken chains (6.8%) and 1 broken loop (1.3%) were identified. The mean chain length (# of transplants) within broken chains was 4.05 compared to 4.69 of ended (completed) chains. Seven of the 19 broken chains were caused by real time swap failures. The most common causes of a broken chain were “medical” (n=8), “no reason” (n=4), and “kidney declined by recipient surgeon” (n=3). One “aborted donor surgery” and one “recipient medical issue” occurred. A donor “renege” occurred in 1 case.

Conclusions: Based on these results broken chains are infrequent and rarely due to a donor renege. The most common cause of broken chains within this KPD program was “medical”.

CITATION INFORMATION: Cowan N, Sinacore J, Gritsch H, Veale J. Analysis of Broken Chains in Kidney Paired Donation During an 8 Year Period within the National Kidney Registry. Am J Transplant. 2016;16 (suppl 3).

  • Tweet
  • Email
  • Print

To cite this abstract in AMA style:

Cowan N, Sinacore J, Gritsch H, Veale J. Analysis of Broken Chains in Kidney Paired Donation During an 8 Year Period within the National Kidney Registry. [abstract]. Am J Transplant. 2016; 16 (suppl 3). https://atcmeetingabstracts.com/abstract/analysis-of-broken-chains-in-kidney-paired-donation-during-an-8-year-period-within-the-national-kidney-registry/. Accessed March 6, 2021.

« Back to 2016 American Transplant Congress

Most Viewed Abstracts

  • This Week
  • This Month
  • All Time
  • Role of Mitochondria, Metabolism and Inflammation: Pathways Influencing Short Term Outcomes Post-Renal Transplantation
    • Factors Influencing Creatinine Rise Following Donor Nephrectomy

    Visit Our Partner Sites

    American Transplant Congress (ATC)

    Visit the official site for the American Transplant Congress »

    American Journal of Transplantation

    The official publication for the American Society of Transplantation (AST) and the American Society of Transplant Surgeons (ASTS) »

    American Society of Transplantation (AST)

    An organization of more than 3000 professionals dedicated to advancing the field of transplantation. »

    American Society of Transplant Surgeons (ASTS)

    The society represents approximately 1,800 professionals dedicated to excellence in transplantation surgery. »

    Copyright © 2013-2021 by American Society of Transplantation and the American Society of Transplant Surgeons. All rights reserved.

    Privacy Policy

    loading Cancel
    Post was not sent - check your email addresses!
    Email check failed, please try again
    Sorry, your blog cannot share posts by email.
    This site uses cookies: Find out more.