ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Kidney transplantation"

  • 2020 American Transplant Congress

    Donor Intervention and Recipient Treatment with Recombinant Human C1 Inhibitor Prevents Delayed Graft Function in a Non-Human Primate Model of Kidney Transplantation

    J. A. Reyes1, C. Blanton1, M. Eerhart1, P. Chlebeck1, M. Springer1, Y. Ponstein2, E. van Amersfoort2, J. Torrealba3, Y. Yankol1, A. D'Allessandro1, L. Fernandez1

    1Surgery, University of Wisconsin, Madison, WI, 2Pharming Technologies BV, Leiden, Netherlands, 3Pathology, UT Soutwestern, Dallas, TX

    *Purpose: There is currently no FDA-approved treatment to prevent delayed graft function (DGF) in kidney transplantation. We have shown that donor or recipient treatment with…
  • 2020 American Transplant Congress

    Survival Benefit of Accepting Kidneys with Acute Kidney Injury

    Y. Yu, J. Long, M. Bowring, S. Yu, J. Motter, T. Ishaque, J. Garonzik Wang, A. Massie, D. Segev

    Department of Surgery, Johns Hopkins School of Medicine, Baltimore, MD

    *Purpose: Accepting an acute kidney injury kidney (AKI) or remaining on the waitlist to receive a better offer is under discussed due to the worse…
  • 2020 American Transplant Congress

    Opioid Utilization Post-Operatively in Kidney Transplantation

    S. Gattis, R. Badell

    Emory Healthcare, Atlanta, GA

    *Purpose: The Centers for Disease Control and Prevention has reported prescription opioid involved deaths increasing since the 1990s. National efforts are being made to fight…
  • 2020 American Transplant Congress

    Prospective Donor-Specific CellUlar Alloresponse Assessment for Immunosuppression MinImization in De Novo Renal Transplantation: Results of a Randomized Controlled Biomarker-Guided Trial

    O. Bestard1, P. Reinke2, F. Bemelman3, O. Viklicky4, M. Koch5, M. Giral6, J. Ruiz7, B. Banas8, E. Crespo1, M. Meneghini1, H. Volk9, J. Grinyo1

    1Kidney transplantation Unit, Bellvitge University Hospital- IDIBELL, L'Hospitalet de Llobregat. Barcelona, Spain, 2Kidney transplantation Unit, Charité - Universitätsmedizin Berlin, Berlin, Germany, 3Kidney transplantation Unit, Amsterdam Medical Centre, Amsterdam, Netherlands, 4Nephrology department, Institute for Clinical and Experimental Medicine (IKEM), Prague, Czech Republic, 5Department of Hepatobiliary Surgery and Transplantation, University Medical Center Hamburg-Eppendorf, Hamburg, Germany, 6Nephrology, Kidney transplantation Unit, Université de Nantes, Nantes, France, 7Nephrology, Hospital Marques de Valdecilla, Santander, Spain, 8Kidney transplantation Unit, University Hospital Regensburg, Regensburg, Germany, 9Institute for Medical Immunology, Charité - Universitätsmedizin Berlin, Berlin, Germany

    *Purpose: Early immunosuppression minimization is associated with higher rates of BPAR. Preformed donor-specific T-cell alloreactivity (DST) assessed with an IFN-γ ELISPOT assay has shown to…
  • 2020 American Transplant Congress

    High-Activity Classical and Alternative Complement Pathway Genotypes – Association with Donor-Specific Antibody-Triggered Injury and Renal Allograft Survival

    R. Reindl-Schwaighofer1, B. Mezö2, F. Eskandary1, A. Heinzel1, M. Wahrmann1, K. Doberer1, A. Heilos3, G. Bond1, J. Kläger4, N. Kozakowski4, H. Haslacher5, R. Oberbauer1, O. Viklický6, P. Hruba6, P. F. Halloran7, K. Rusai3, Z. Prohászka8, G. A. Böhmig1

    1Department of Medicine III, Medical University of Vienna, Vienna, Austria, 2Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary, 3Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria, 4Department of Pathology, Medical University of Vienna, Vienna, Austria, 5Department of Laboratory Medicine, Medical University of Vienna, Vienna, Austria, 6Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic, 7Alberta Transplant Applied Genomics Centre, University of Alberta, Edmonton, AB, Canada, 8Department of Medicine III, Hungarian Academy of Sciences and Semmelweis University, Budapest, Hungary

    *Purpose: Complement may contribute to donor-specific antibody (DSA)-triggered transplant injury. Here, we investigated whether the intrinsic strength of classical (CP) and alternative complement pathways (AP)…
  • 2020 American Transplant Congress

    Kidney after Intestinal Transplantation: A Comparison with Combined Kidney with Intestinal Transplant. A UNOS Database Analysis

    A. Sharfuddin, M. Panezai, O. Adebiyi, T. Taber, M. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: There is limited data on outcomes for patients receiving a isolated kidney transplant (KAIT) after any prior Multi-organ or Isolated Intestinal transplant (IT). We…
  • 2020 American Transplant Congress

    Significant Improvement in Short and Long-Term Kidney Transplant Survival Despite Stagnant Rates of Delayed Graft Function

    J. Schold1, S. Arrigain2, E. Poggio3

    1Cleveland Clinic Foundation, Cleveland, OH, 2Quantitative Health Sciences, Cleveland Clinic Foundation, Cleveland, OH, 3Nephrology, Cleveland Clinic Foundation, Cleveland, OH

    *Purpose: Delayed Graft Function (DGF) is routinely characterized as attributing to significant morbidity and mortality among kidney transplant recipients. While there are diverse potential mechanisms…
  • 2020 American Transplant Congress

    Prevalence of Diabetes after Kidney Donation

    A. J. Haugen1, S. Hallan2, K. Birkeland1, A. Reisæter1, A. Hartmann1, H. Holdaas1, G. Mjøen1

    1Transplant Medicine, Oslo University Hospital, Oslo, Norway, 2Nephrology, St. Olavs Hospital, Trondheim, Norway

    *Purpose: Kidney donors may be at increased risk of hypertension and end-stage renal disease after donation. If diabetes mellitus is more common in donors remains…
  • 2020 American Transplant Congress

    The Urine Qisant Score: Non-Invasive, Accurate, Diagnosis and Prediction of Kidney Transplant Rejection

    J. Y. Yang1, R. Sarwal1, T. Sigdel1, I. Damm1, B. Rosenbaum1, J. Liberto1, C. Chan-On1, J. Alberu2, F. Vincenti1, M. M. Sarwal1

    1University of California San Francisco, San Francisco, CA, 2University of Mexico, Instituto Nacional De Ciencias Medicas y Nutricion, San Francisco, CA

    *Purpose: Accurate and non-invasive monitoring of renal allografts post-transplant is essential for early detection of acute rejection (AR) and to directly impact the long-term survival…
  • 2020 American Transplant Congress

    Impact of Variation in Histological Assessments and Their Impact on Clinical Trial Enrollment and Endpoints – Preliminary Report of The Gen04 Study

    W. Park1, M. Ryan2, L. Herrera Hernandez3, M. Smith2, X. Geiger4, T. Sandor5, L. Cornell3, M. Stegall1

    1Transplant Center, Mayo Clinic, Rochester, MN, 2Laboratory Medicine and Pathology, Mayo Clinic, Scottsdale, AZ, 3Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN, 4Laboratory Medicine and Pathology, Mayo Clinic, Jacksonville, FL, 5Pathology, University of Szegad, Szegad, Hungary

    *Purpose: Renal allograft histology is often used as inclusion criteria for clinical trials. This includes Gen04, which is an NIH sponsored multi-center clinical trial involving…
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