Session Time: 3:15pm-4:45pm
Presentation Time: 4:15pm-4:27pm
*Purpose: Kidney donors may be at increased risk of hypertension and end-stage renal disease after donation. If diabetes mellitus is more common in donors remains unclear. We have evaluated a large Norwegian kidney donor cohort and assessed prevalence of diabetes.
*Methods: Follow-up data were retrieved from past kidney donors from the time period 2008-2013. The diagnosis of diabetes was self-reported or based on fasting glucose >7 mmol/l, non-fasting glucose > 11.1 mmol/l or HbA1C >6.5 %. The prevalence of self-reported diabetes was compared against a control population from the HUNT 3 survey consisting of individuals who were healthy at the time of the donor`s nephrectomy, but not necessarily at the time of cross sectional follow-up. In addition to the HUNT3 survey, each control person was also assessed in similar time periods as the donor nephrectomies (HUNT 1 performed in 1984-1986 and HUNT2 performed in 1995-1997, respectively). Stratified logistic regression was used to evaluate if being a kidney donor was associated with increased risk of self-reported diabetes at time of cross-sectional survey. Adjustments were made for gender, age at follow up, smoking at baseline, BMI at baseline, systolic blood pressure at baseline, time since donation and stratified for time of donation before or after 1995.
*Results: A total of 1029 donors and 16084 controls eligible for donation were included. Mean age of the donors was 56 years at the time of follow-up. Forty-four per cent were male and mean observation time was eleven years after donation. Based on the diagnostic criteria 49/1018 (4.8 %) donors had diabetes at the time of follow up. 42/1018 (4.1 %) donors had self reported diabetes at follow-up. In adjusted stratified logistic regression analyses, when comparing the self-reported diagnosis of diabetes with controls, odds ratio for diabetes was at 1.27 (confidence interval 0.85-1.91, P=0.24).
*Conclusions: In this study, the outcome of self-reported diabetes was not significantly increased in kidney donors compared with healthy controls long after donation.
To cite this abstract in AMA style:Haugen AJ, Hallan S, Birkeland K, Reisæter A, Hartmann A, Holdaas H, Mjøen G. Prevalence of Diabetes after Kidney Donation [abstract]. Am J Transplant. 2020; 20 (suppl 3). https://atcmeetingabstracts.com/abstract/prevalence-of-diabetes-after-kidney-donation/. Accessed May 18, 2021.
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