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American Transplant Congress abstracts

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Articles tagged "Intestinal transplantation"

  • 2020 American Transplant Congress

    Pediatric Renal Transplant after Intestinal Transplant – Technical Challenges and Outcomes

    A. Amin, B. Emmanuel, Y. Chang, G. Bond, A. Khanna, K. Soltys, R. Sindhi, A. Tevar, A. Humar, G. Mazariegos, A. Ganoza

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: There is no data in the literature about outcomes of pediatric intestinal transplant (IT) recipients, who require renal transplant after intestinal transplant (RTAIT). The…
  • 2020 American Transplant Congress

    Correlation of CMV and EBV DNAemia in the Development of Invasive Fungal Disease among Pediatric Intestinal and Liver Transplant Recipients

    B. M. Chatani1, J. Garcia2, T. Beduschi3, A. Tekin3, R. Vianna3, I. A. Gonzalez1

    1Pediatric Infectious Disease, University of Miami Miller School of Medicine, Miami, FL, 2Pediatric Gastroenterology, University of Miami Miller School of Medicine, Miami, FL, 3Miami Transplant Institute, Miami, FL

    *Purpose: Invasive fungal disease (IFD) among pediatric solid organ transplant recipients is a relatively rare event, however often results in death. There are many factors…
  • 2020 American Transplant Congress

    A Mouse Model of Paratopic Intestinal Transplantation to Delineate GVHD-Free Alloimmune Rejection Responses

    A. Dangi1, J. Wang2, A. Joseph3, J. Roper3, N. Surana4, X. Luo1

    1Nephrology/Medicine, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC, 3Gastroenterology/Medicine, Duke University, Durham, NC, 4Molecular Genetics and Microbiology, Duke University, Durham, NC

    *Purpose: Current clinical practice of intestinal transplantation is limited due to a high rate of graft failure and patient mortality. In the present study, we…
  • 2020 American Transplant Congress

    Chronic Hyperammonemia an Important Cause of Morbidity in Isolated Intestine Transplant Patients with Venous Outflow to the Vena Cava

    R. S. Mangus, C. A. Kubal, T. Burch, B. Ekser, P. Mihaylov, J. Fridell

    Indiana University, Indianapolis, IN

    *Purpose: There are limited options for superior mesenteric vein (SMV) outflow in isolated intestine transplant (ITx), the two most common being anastomosis to the recipient…
  • 2020 American Transplant Congress

    Epidemiology of Clostridioides Difficile Infection in Intestinal and Multivisceral Transplant Patients at a Single Transplant Center

    A. Modi1, B. Gonzalez2, K. Brizendine1

    1Infectious Disease, Cleveland Clinic, Cleveland, OH, 2Pediatric Infectious Disease, Cleveland Clinic, Cleveland, OH

    *Purpose: Solid organ transplant (SOT) recipients face increased risk of Clostridioides difficile infection (CDI), with reported CDI incidence of 7.4%-20% far exceeding that of the…
  • 2020 American Transplant Congress

    Vascular Complications in Pediatric Intestine Transplant Recipients – Treatment Strategies and Outcomes

    A. Amin, Y. Chang, B. Emmanuel, A. Ganoza, G. Bond, A. Khanna, K. Soltys, R. Sindhi, G. Mazariegos

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: To identify vascular complications in pediatric intestine transplant (IT) recipients, evaluate treatment strategies, and review their impact on graft loss and patient mortality.*Methods: Retrospective…
  • 2020 American Transplant Congress

    Multicenter Evaluation of Cytomegalovirus Infection Following Intestinal and Multivisceral Transplantation

    M. Segovia1, Y. Patel1, S. Nagai2, D. Sudan1, S. Jafri2

    1Duke University Hospital, Chapel Hill, NC, 2Henry Ford Hospital, Detroit, MI

    *Purpose: Evaluate factors related to incidence and outcomes of cytomegalovirus (CMV) infection after isolated intestinal transplantation (IT) and multivisceral transplantation (MVT).*Methods: Retrospective evaluation of 32…
  • 2020 American Transplant Congress

    Megacystis Microcolon Intestinal Hypoperistalsis Syndrome: A Case Series with Long Term Follow Up and Prolonged Survival

    K. M. Prathapan1, V. Raghu1, A. Ganoza2, K. Ackerman1, T. Presel1, J. A. Yaworski1, W. Sevilla1, D. King1, J. Rudolph1, F. Alissa1

    1Division of Pediatric Gastroenterology, Hepatology and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 2Hillman Center for Pediatric Transplantation, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA

    *Purpose: To describe clinical characteristics, management and survival in a cohort of Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) patients.*Methods: We conducted a retrospective chart review of MMIHS…
  • 2020 American Transplant Congress

    Type 3 Innate Lymphoid Cells Are Associated with a Successful Intestinal Transplant

    J. Kang1, K. Loh1, L. Belyayev1, S. Moturi1, M. Sadat1, K. Khan1, A. Duttargi1, Y. Gusev2, K. Bhuvaneshwar2, H. Ressom2, J. Hawksworth1, C. Matsumoto1, T. Fishbein1, A. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2Georgetown University, Washington, DC

    *Purpose: Innate lymphoid cells (ILCs) play fundamental roles in mucosal barrier functionality and tissue homeostasis. We hypothesized that protective IL-22-producing NKp44+ILC3 subsets are reduced under…
  • 2020 American Transplant Congress

    The Role of Th17 Polarized T Regulatory Cells in Intestinal Transplant Rejection

    L. Belyayev1, M. Sadat2, J. Kang2, K. Loh2, A. Duttargi2, S. Moturi2, K. Khan2, J. Hawksworth2, C. Matsumoto2, T. Fishbein2, A. Kroemer2

    1Walter Reed National Military Medical Center, Bethesda, MD, 2MedStar Georgetown Transplant Institute, Washington, DC

    *Purpose: Despite profound advances in immunosuppression, intestinal transplantation (ITx) is plagued by frequent cellular rejection. T regulatory cells (Tregs) are key in mitigating immune cell…
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