ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Intestinal transplantation"

  • 2020 American Transplant Congress

    Chronic Hyperammonemia an Important Cause of Morbidity in Isolated Intestine Transplant Patients with Venous Outflow to the Vena Cava

    R. S. Mangus, C. A. Kubal, T. Burch, B. Ekser, P. Mihaylov, J. Fridell

    Indiana University, Indianapolis, IN

    *Purpose: There are limited options for superior mesenteric vein (SMV) outflow in isolated intestine transplant (ITx), the two most common being anastomosis to the recipient…
  • 2020 American Transplant Congress

    Epidemiology of Clostridioides Difficile Infection in Intestinal and Multivisceral Transplant Patients at a Single Transplant Center

    A. Modi1, B. Gonzalez2, K. Brizendine1

    1Infectious Disease, Cleveland Clinic, Cleveland, OH, 2Pediatric Infectious Disease, Cleveland Clinic, Cleveland, OH

    *Purpose: Solid organ transplant (SOT) recipients face increased risk of Clostridioides difficile infection (CDI), with reported CDI incidence of 7.4%-20% far exceeding that of the…
  • 2020 American Transplant Congress

    Vascular Complications in Pediatric Intestine Transplant Recipients – Treatment Strategies and Outcomes

    A. Amin, Y. Chang, B. Emmanuel, A. Ganoza, G. Bond, A. Khanna, K. Soltys, R. Sindhi, G. Mazariegos

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: To identify vascular complications in pediatric intestine transplant (IT) recipients, evaluate treatment strategies, and review their impact on graft loss and patient mortality.*Methods: Retrospective…
  • 2020 American Transplant Congress

    Multicenter Evaluation of Cytomegalovirus Infection Following Intestinal and Multivisceral Transplantation

    M. Segovia1, Y. Patel1, S. Nagai2, D. Sudan1, S. Jafri2

    1Duke University Hospital, Chapel Hill, NC, 2Henry Ford Hospital, Detroit, MI

    *Purpose: Evaluate factors related to incidence and outcomes of cytomegalovirus (CMV) infection after isolated intestinal transplantation (IT) and multivisceral transplantation (MVT).*Methods: Retrospective evaluation of 32…
  • 2020 American Transplant Congress

    Megacystis Microcolon Intestinal Hypoperistalsis Syndrome: A Case Series with Long Term Follow Up and Prolonged Survival

    K. M. Prathapan1, V. Raghu1, A. Ganoza2, K. Ackerman1, T. Presel1, J. A. Yaworski1, W. Sevilla1, D. King1, J. Rudolph1, F. Alissa1

    1Division of Pediatric Gastroenterology, Hepatology and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, 2Hillman Center for Pediatric Transplantation, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA

    *Purpose: To describe clinical characteristics, management and survival in a cohort of Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) patients.*Methods: We conducted a retrospective chart review of MMIHS…
  • 2020 American Transplant Congress

    Type 3 Innate Lymphoid Cells Are Associated with a Successful Intestinal Transplant

    J. Kang1, K. Loh1, L. Belyayev1, S. Moturi1, M. Sadat1, K. Khan1, A. Duttargi1, Y. Gusev2, K. Bhuvaneshwar2, H. Ressom2, J. Hawksworth1, C. Matsumoto1, T. Fishbein1, A. Kroemer1

    1MedStar Georgetown Transplant Institute, Washington, DC, 2Georgetown University, Washington, DC

    *Purpose: Innate lymphoid cells (ILCs) play fundamental roles in mucosal barrier functionality and tissue homeostasis. We hypothesized that protective IL-22-producing NKp44+ILC3 subsets are reduced under…
  • 2020 American Transplant Congress

    The Role of Th17 Polarized T Regulatory Cells in Intestinal Transplant Rejection

    L. Belyayev1, M. Sadat2, J. Kang2, K. Loh2, A. Duttargi2, S. Moturi2, K. Khan2, J. Hawksworth2, C. Matsumoto2, T. Fishbein2, A. Kroemer2

    1Walter Reed National Military Medical Center, Bethesda, MD, 2MedStar Georgetown Transplant Institute, Washington, DC

    *Purpose: Despite profound advances in immunosuppression, intestinal transplantation (ITx) is plagued by frequent cellular rejection. T regulatory cells (Tregs) are key in mitigating immune cell…
  • 2020 American Transplant Congress

    Allograft Repopulating Recipient B Cells after Human Intestinal Transplantation and Their Association with Donor Specific Antibody Secretion and Rejection

    E. Waffarn1, J. Fu1, K. Frangaj1, W. Meng2, A. M. Rosenfeld2, M. Li3, K. Rodgers1, R. Vasilescu3, E. T. Luning Prak2, A. Griesemer1, T. Kato4, M. Martinez5, M. Sykes1

    1Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, 2Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 3Department of Pathology, Columbia University, New York, NY, 4Department of Surgery, Columbia University, New York, NY, 5Department of Pediatrics, Columbia University, New York, NY

    *Purpose: Alloantibodies produced by recipient B cells are associated with rejection after intestinal transplantation (ITx) and negatively impact patient and graft survival. However, the dynamics…
  • 2020 American Transplant Congress

    Intestinal Retransplantation: Survival Outcomes Similar to Primary Transplantation

    C. Beyersdorf, L. Vargas, D. Mercer, W. Grant, A. Langnas, S. Merani

    University of Nebraska Medical Center, Omaha, NE

    *Purpose: Isolated and multivisceral intestinal transplantation is indicated for patients with life threatening complications of intestinal failure. Intestinal retransplantation has been performed in select intestinal…
  • 2020 American Transplant Congress

    Kidney after Intestinal Transplantation: A Comparison with Combined Kidney with Intestinal Transplant. A UNOS Database Analysis

    A. Sharfuddin, M. Panezai, O. Adebiyi, T. Taber, M. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: There is limited data on outcomes for patients receiving a isolated kidney transplant (KAIT) after any prior Multi-organ or Isolated Intestinal transplant (IT). We…
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