ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Intestinal transplantation"

  • 2020 American Transplant Congress

    Allograft Repopulating Recipient B Cells after Human Intestinal Transplantation and Their Association with Donor Specific Antibody Secretion and Rejection

    E. Waffarn1, J. Fu1, K. Frangaj1, W. Meng2, A. M. Rosenfeld2, M. Li3, K. Rodgers1, R. Vasilescu3, E. T. Luning Prak2, A. Griesemer1, T. Kato4, M. Martinez5, M. Sykes1

    1Columbia Center for Translational Immunology, Department of Medicine, Columbia University, New York, NY, 2Department of Pathology and Laboratory Medicine, University of Pennsylvania, Philadelphia, PA, 3Department of Pathology, Columbia University, New York, NY, 4Department of Surgery, Columbia University, New York, NY, 5Department of Pediatrics, Columbia University, New York, NY

    *Purpose: Alloantibodies produced by recipient B cells are associated with rejection after intestinal transplantation (ITx) and negatively impact patient and graft survival. However, the dynamics…
  • 2020 American Transplant Congress

    Intestinal Retransplantation: Survival Outcomes Similar to Primary Transplantation

    C. Beyersdorf, L. Vargas, D. Mercer, W. Grant, A. Langnas, S. Merani

    University of Nebraska Medical Center, Omaha, NE

    *Purpose: Isolated and multivisceral intestinal transplantation is indicated for patients with life threatening complications of intestinal failure. Intestinal retransplantation has been performed in select intestinal…
  • 2020 American Transplant Congress

    Kidney after Intestinal Transplantation: A Comparison with Combined Kidney with Intestinal Transplant. A UNOS Database Analysis

    A. Sharfuddin, M. Panezai, O. Adebiyi, T. Taber, M. Yaqub

    Indiana University School of Medicine, Indianapolis, IN

    *Purpose: There is limited data on outcomes for patients receiving a isolated kidney transplant (KAIT) after any prior Multi-organ or Isolated Intestinal transplant (IT). We…
  • 2020 American Transplant Congress

    Trends in Intestinal and Multivisceral Transplantation in the United States over 30 Years

    M. L. Samoylova1, J. Yerxa1, B. I. Shaw1, S. Horslen2, S. Jafri3, A. Mavis4, T. Schiano5, B. Summers6, A. S. Barbas1, D. L. Sudan1, M. C. Segovia4

    1Surgery, Duke University Hospital, Durham, NC, 2Ped Gastroenterology, Seattle Childrens' Hospital, Seattle, WA, 3Gastroenterology, Henry Ford Hospital, Detroit, MI, 4Gastroenterology, Duke University Hospital, Durham, NC, 5Gastroenterology, Mt Sinai Hospital, New York, NY, 6Transplant Pharmacy, Henry Ford Hospital, Detroit, MI

    *Purpose: We describe trends in intestinal transplantation use and outcomes over time in the USA.*Methods: We use the cohort of intestinal and multivisceral transplants 1990-2019…
  • 2020 American Transplant Congress

    A Nonhuman Primate Model of Intestinal Transplantation – Technical Aspects and Early Outcomes

    R. Schmitz1, J. Yoon1, M. Song1, E. Jelly2, A. P. Wax2, S. J. Knechtle1, D. L. Sudan1, J. Kwun1

    1Department of Surgery, Duke University Medical Center, Durham, NC, 2Department of Biomedical Engineering, Duke University, Durham, NC

    *Purpose: Intestinal transplantation (IT) is the treatment of choice for patients with irreversible intestinal failure that experience complications from total parenteral nutrition. Long-term outcomes after…
  • 2020 American Transplant Congress

    Pediatric Renal Transplant after Intestinal Transplant – Technical Challenges and Outcomes

    A. Amin, B. Emmanuel, Y. Chang, G. Bond, A. Khanna, K. Soltys, R. Sindhi, A. Tevar, A. Humar, G. Mazariegos, A. Ganoza

    University of Pittsburgh Medical Center, Pittsburgh, PA

    *Purpose: There is no data in the literature about outcomes of pediatric intestinal transplant (IT) recipients, who require renal transplant after intestinal transplant (RTAIT). The…
  • 2020 American Transplant Congress

    Correlation of CMV and EBV DNAemia in the Development of Invasive Fungal Disease among Pediatric Intestinal and Liver Transplant Recipients

    B. M. Chatani1, J. Garcia2, T. Beduschi3, A. Tekin3, R. Vianna3, I. A. Gonzalez1

    1Pediatric Infectious Disease, University of Miami Miller School of Medicine, Miami, FL, 2Pediatric Gastroenterology, University of Miami Miller School of Medicine, Miami, FL, 3Miami Transplant Institute, Miami, FL

    *Purpose: Invasive fungal disease (IFD) among pediatric solid organ transplant recipients is a relatively rare event, however often results in death. There are many factors…
  • 2020 American Transplant Congress

    A Mouse Model of Paratopic Intestinal Transplantation to Delineate GVHD-Free Alloimmune Rejection Responses

    A. Dangi1, J. Wang2, A. Joseph3, J. Roper3, N. Surana4, X. Luo1

    1Nephrology/Medicine, Duke University, Durham, NC, 2Surgery, Duke University, Durham, NC, 3Gastroenterology/Medicine, Duke University, Durham, NC, 4Molecular Genetics and Microbiology, Duke University, Durham, NC

    *Purpose: Current clinical practice of intestinal transplantation is limited due to a high rate of graft failure and patient mortality. In the present study, we…
  • 2020 American Transplant Congress

    Chronic Hyperammonemia an Important Cause of Morbidity in Isolated Intestine Transplant Patients with Venous Outflow to the Vena Cava

    R. S. Mangus, C. A. Kubal, T. Burch, B. Ekser, P. Mihaylov, J. Fridell

    Indiana University, Indianapolis, IN

    *Purpose: There are limited options for superior mesenteric vein (SMV) outflow in isolated intestine transplant (ITx), the two most common being anastomosis to the recipient…
  • 2020 American Transplant Congress

    Epidemiology of Clostridioides Difficile Infection in Intestinal and Multivisceral Transplant Patients at a Single Transplant Center

    A. Modi1, B. Gonzalez2, K. Brizendine1

    1Infectious Disease, Cleveland Clinic, Cleveland, OH, 2Pediatric Infectious Disease, Cleveland Clinic, Cleveland, OH

    *Purpose: Solid organ transplant (SOT) recipients face increased risk of Clostridioides difficile infection (CDI), with reported CDI incidence of 7.4%-20% far exceeding that of the…
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