Articles tagged "Intestinal transplantation"

2022 American Transplant Congress
The Effect of COVID-19 Pandemic in Intestinal Rehabilitation and Transplant Patients – International Multicenter Survey
M. Segovia¹, M. Fernandez², S. Jafri³, T. Schiano⁴, S. Horslen⁵, C. Rumbo², C. Zanfi⁶, A. Testro⁷, L. Sharkey⁸, F. Braun⁹, H. Vilca Melendez¹⁰, R. Sanchez Claria¹¹, L. Ceulemans¹², T. Hibi¹³, D. Ramish², G. Noel¹, G. Dijkstra¹⁴, P. Friend¹⁵, F. Lacaille¹⁶, D. Sudan¹, G. Mazariegos¹⁷, J. Yap¹⁸, G. Herlenius¹⁹, H. Solar², G. Gondolesi²
¹Duke, Durham, NC, ²Favaloro, Buenos Aires, Argentina, ³Henry Ford, Detroit, MI, ⁴Mount Sinai, New York, NY, ⁵UPMC, Edgeworth, PA, ⁶U Bologna, Bologna, Italy, ⁷Austin Health, Melbourne, Australia, ⁸Cambridge, Cambridge, United Kingdom, ⁹Schleswig-Holstein, Kiel, Germany, ¹⁰King's College, London, United Kingdom, ¹¹Hosp Italiano, Buenos Aires, Argentina, ¹²U Leuven, Brussels, Belgium, ¹³Kumamoto Univ, Kumamoto, Japan, ¹⁴U Groningen, Groningen, Netherlands, ¹⁵U Oxford, Oxford, United Kingdom, ¹⁶Necker-Enfants Malades, Paris, France, ¹⁷UPMC, Pittsburgh, PA, ¹⁸U Melbourne, Melbourne, Australia, ¹⁹U Sahlgrenska, Gothenburg, Sweden
*Purpose: It has been proposed that patients with intestinal failure (IF) and intestine transplant (IT) are at higher risk of severe complications of COVID-19 due…
2022 American Transplant Congress
The Outcome of Clostridioides Difficile Infection in Hospitalized Intestinal Transplant Recipients
W. Amjad¹, T. Schiano², A. Malik³, M. Segovia⁴, S. Jafri⁵
¹Clinical Investigation, Harvard Medical School, Boston, MA, ²Intestinal and Liver Transplantation, Mount Sinai Medical Center, New York, NY, ³Internal Medicine, Saint Joseph's Medical Center, Stockton, CA, ⁴Small Intestine and Liver Transplant, Duke University School of Medicine, Durham, NC, ⁵Gastroenterology and Hepatology, Henry Ford Health System, Detroit, MI
*Purpose: Organ transplantation is a known risk factor of Clostridioides difficile infection. There is limited published data on the frequency and impact of CDI in…
2022 American Transplant Congress
Adenovirus Enteritis Following Intestinal Transplantation
S. Jafri¹, A. Mavis², J. Weiner³, M. C. Segovia²
¹Henry Ford Health System, Detroit, MI, ²Duke University, Durham, NC, ³Columbia, New York, NY
*Purpose: Intestinal transplant is a life-saving therapy for intestinal failure. Adenovirus Enteritis (AE) is an unusual infection identified on biopsy or serology following intestine or…
2022 American Transplant Congress
Surveillance with Protocol Biopsies for Rejection Significantly Impacts Survival Following Intestine Transplant
J. R. Sherwood¹, Y. Ichkhanian², N. Beltran³, S. Nagai³, S. Jafri⁴
¹Wayne State School of Medicine, Detroit, MI, ²Department of Internal Medicine, Henry Ford Hospital, Detroit, MI, ³Department of Transplant Surgery, Henry Ford Hospital, Detroit, MI, ⁴Division of Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI
*Purpose: Frequent surveillance biopsy is required on the first month post intestinal transplant(IT) due to high-risk of acute rejection. However, the utility and the frequency…
2022 American Transplant Congress
Noninvasive Biomarkers for Allograft Monitoring After Intestinal Transplantation: Promising Early Results from a Novel Peptide, REG3α
C. P. Smullin¹, R. S. Venick², E. A. Marcus², B. V. Naini³, D. G. Farmer⁴
¹David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ²Pediatrics, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ³Pathology, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA, ⁴Surgery, David Geffen School of Medicine at University of California Los Angeles, Los Angeles, CA
*Purpose: There is an urgent need for the discovery and application of noninvasive biomarkers to detect allograft rejection after intestinal transplantation (ITx). Calprotectin and citrulline…
2022 American Transplant Congress
25 Years of a Standardized Living Donor (LD) Intestinal Transplant Technique – What Has Been Achieved?
R. Gruessner¹, A. C. Gruessner²
¹SUNY Downstate Medical Center, Brooklyn, NY, ²SUNY Downstate Medical Center, Brooklyn, MA
*Purpose: The indication for intestinal transplantation (ITX) is irreversible intestinal failure with dependence on total parenteral nutrition (TPN). Most intestinal transplants are from deceased donors…
2022 American Transplant Congress
Passenger Lymphocyte Syndrome Presented as Hemolytic Anemia After Small Bowel Transplantation: A Case Report
M. Kim¹, D. Kim¹, J. Lim¹, J. Jung², J. Kim³, J. Hwang¹
¹Eunpyeong St. Mary's Hospital, Eunpyeong-gu, Seoul, Korea, Republic of, ²Seoul St. Mary's Hospital, Seoul, Korea, Republic of, ³Uijeongbu Eulji Medical Center, Uijeongbu, Korea, Republic of
*Purpose: The passenger lymphocyte syndrome (PLS) induces hemolytic anemia after minor ABO mismatched organ transplantation. We experienced a case of PLS with hemolysis after small…
2022 American Transplant Congress
Induction of Tolerance After Intestinal Transplantation in a Porcine Model
S. Merl, R. Jones, B. Chen, M. Sykes, K. Yamada, J. Weiner
Columbia Center for Translational Immunology, Columbia University, New York, NY
*Purpose: We describe a case of tolerance from our study investigating multilineage chimerism under immunological conditions after intestinal transplantation using a porcine model with defined…
2022 American Transplant Congress
Comparative Case Study of Mycobacterium Infections in Pediatric Post Intestinal Transplant
S. Yerina¹, R. Kanthula¹, Y. Rekhtman², S. Kaufman¹, U. Ekong¹, N. Yazigi¹, T. Fishbein¹, A. Kroemer¹, C. Matsumoto¹, K. Khan¹
¹Transplant, Georgetown University Hospital, Washington, DC, ²GI and Nutrition, Prisma Health Midlands Children's Hospital, Columbia, SC
*Purpose: We describe two rare and challenging post pediatric intestinal transplant cases with both Mycobacterium (M) Abscessus and Mycobacterium (M) Immunogenum in post surgical site…
2021 American Transplant Congress
Segmental Susceptibility of Intestinal Stem Cells to Cold Storage Preservation Injury in a Porcine Model
E. K. Ludwig¹, N. Abraham², D. Sudan², A. Barbas², C. Schaaf¹, J. Freund¹, A. S. Stewart¹, B. Veerasammy¹, L. M. Gonzalez¹
¹North Carolina State University, Raleigh, NC, ²Duke University, Durham, NC
*Purpose: Cold storage (CS) is the current gold standard preservation method for small bowel (SB) prior to transplantation. However, CS can cause epithelial detachment, sloughing,…

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