Articles tagged "Intestinal transplantation"

2020 American Transplant Congress
Vascular Complications in Pediatric Intestine Transplant Recipients – Treatment Strategies and Outcomes
A. Amin, Y. Chang, B. Emmanuel, A. Ganoza, G. Bond, A. Khanna, K. Soltys, R. Sindhi, G. Mazariegos
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To identify vascular complications in pediatric intestine transplant (IT) recipients, evaluate treatment strategies, and review their impact on graft loss and patient mortality.*Methods: Retrospective…
2020 American Transplant Congress
Multicenter Evaluation of Cytomegalovirus Infection Following Intestinal and Multivisceral Transplantation
M. Segovia¹, Y. Patel¹, S. Nagai², D. Sudan¹, S. Jafri²
¹Duke University Hospital, Chapel Hill, NC, ²Henry Ford Hospital, Detroit, MI
*Purpose: Evaluate factors related to incidence and outcomes of cytomegalovirus (CMV) infection after isolated intestinal transplantation (IT) and multivisceral transplantation (MVT).*Methods: Retrospective evaluation of 32…
2020 American Transplant Congress
Megacystis Microcolon Intestinal Hypoperistalsis Syndrome: A Case Series with Long Term Follow Up and Prolonged Survival
K. M. Prathapan¹, V. Raghu¹, A. Ganoza², K. Ackerman¹, T. Presel¹, J. A. Yaworski¹, W. Sevilla¹, D. King¹, J. Rudolph¹, F. Alissa¹
¹Division of Pediatric Gastroenterology, Hepatology and Nutrition, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA, ²Hillman Center for Pediatric Transplantation, UPMC Children's Hospital of Pittsburgh, Pittsburgh, PA
*Purpose: To describe clinical characteristics, management and survival in a cohort of Megacystis-microcolon-intestinal hypoperistalsis syndrome (MMIHS) patients.*Methods: We conducted a retrospective chart review of MMIHS…
2020 American Transplant Congress
Type 3 Innate Lymphoid Cells Are Associated with a Successful Intestinal Transplant
J. Kang¹, K. Loh¹, L. Belyayev¹, S. Moturi¹, M. Sadat¹, K. Khan¹, A. Duttargi¹, Y. Gusev², K. Bhuvaneshwar², H. Ressom², J. Hawksworth¹, C. Matsumoto¹, T. Fishbein¹, A. Kroemer¹
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Georgetown University, Washington, DC
*Purpose: Innate lymphoid cells (ILCs) play fundamental roles in mucosal barrier functionality and tissue homeostasis. We hypothesized that protective IL-22-producing NKp44+ILC3 subsets are reduced under…
2020 American Transplant Congress
The Role of Th17 Polarized T Regulatory Cells in Intestinal Transplant Rejection
L. Belyayev¹, M. Sadat², J. Kang², K. Loh², A. Duttargi², S. Moturi², K. Khan², J. Hawksworth², C. Matsumoto², T. Fishbein², A. Kroemer²
¹Walter Reed National Military Medical Center, Bethesda, MD, ²MedStar Georgetown Transplant Institute, Washington, DC
*Purpose: Despite profound advances in immunosuppression, intestinal transplantation (ITx) is plagued by frequent cellular rejection. T regulatory cells (Tregs) are key in mitigating immune cell…
2019 American Transplant Congress
Viral Enteritis in Intestinal Transplant Recipients
A. Servais, M. Vacha, D. F. Florescu, M. Keck
Nebraska Medicine, Omaha, NE
*Purpose: To evaluate viral enteritis episodes in intestinal transplant recipients (ITR)*Methods: This retrospective review included ITR transplanted between January 2008 and December 2016. Data for…
2019 American Transplant Congress
The Role of the T Regulatory Cell Compartment in Intestinal Transplant Patients: Helpful or Unhinged?
L. Belyayev¹, M. Sadat², K. Loh³, S. Moturi², K. Khan², J. Hawksworth², C. Matsumoto², T. M. Fishbein², A. Kroemer²
¹Surgery, Walter Reed National Military Medical Center, Bethesda, MD, ²Transplant, MedStar Georgetown Transplant Institute, Washington D.C., DC, ³Pediatrics, Children’s National Medical Center, Washington D.C., DC
*Purpose: The T regulatory (Treg) cell compartment has now been established as a key player in dampening T helper 17 (Th17) mediated inflammation, managing self-tolerance,…
2019 American Transplant Congress
Challenges to Inpatient Management Post Abdominal Wall Transplant (AWT) – From App’s Perspective
K. Hattori, D. Sudan, K. Ravindra
Duke University hospital, Durham, NC
*Purpose: To highlight the unique features of caring for an AWT recipient and identify areas of improvement for future cases*Methods: AWT is an innovative adjunct…
2019 American Transplant Congress
An International Multicentre Validation Study of the Toronto Listing Criteria for Pediatric Intestinal Transplant
A. J. Roberts¹, P. W. Wales², S. V. Beath³, H. M. Evans¹, J. Hind⁴, T. Wong⁵, D. Mercer⁶, J. Yap⁷, C. Belza⁸, D. Grant⁹, Y. Avitzur¹⁰
¹Department of Paediatric Gastroenterology, Starship Child Health - Auckland District Health Board, Auckland, New Zealand, ²Division of General & Thoracic Surgery, Hospital for Sick Children, University of Toronto,, Group for Improvement of Intestinal Function and Treatment (GIFT), Transplant Centre, Toronto, ON, Canada, ³The Liver Unit, Birmingham Children’s Hospital, Birmingham, United Kingdom, ⁴Paediatric Liver, GI & Nutrition Centre, King's College Hospital, London, United Kingdom, ⁵The Liver Unit, Birmingham Children's Hospital, Birmingham, United Kingdom, ⁶Children’s Hospital and Medical Centre, Omaha, NE, ⁷Department of Pediatrics, University of Alberta, Edmonton, AB, Canada, ⁸Group for Improvement of Intestinal Function and Treatment (GIFT), Transplant Centre, Toronto, ON, Canada, ⁹Department of Surgery, Hospital for Sick Children, University of Toronto, Toronto, ON, Canada, ¹⁰Division of Gastroenterology, Hepatology & Nutrition, Group for Improvement of Intestinal Function and Treatment (GIFT), Transplant Centre, Toronto, ON, Canada
*Purpose: Current intestinal transplantation (IT) listing criteria from 2001 have limited ability to predict the need for IT in the current era of intestinal failure…
2019 American Transplant Congress
Surgical Management Of Five Hundred Patients With Chronic Gut Failure At A Single Center: Autologous Reconstruction Versus Transplantation
S. Armanyous, Y. Fouda, M. Fujiki, N. Parekh, M. Osman, R. Girlanda, K. Hashimoto, G. Costa, K. Abu-Elmagd
Cleveland Clinic, Cleveland, OH
*Purpose: To define the evolving role of autologous gut reconstruction (AGR) in the management of total parenteral nutrition (TPN)-dependent-chronic gut failure (CGF) patients with special…