Articles tagged "Intestinal transplantation"

2021 American Transplant Congress
The Impact of Early Narcotic Administration on Intestinal Transplantation Survival at an Urban Medical Center
L. Maliekal¹, N. Beltran², Y. Muszkat², S. Nagai², S. Jafri²
¹School of Medicine, Wayne State University School of Medicine, Detroit, MI, ²Department of Gastroenterology, Henry Ford Hospital, Detroit, MI
*Purpose: The impact of early narcotic administration on intestinal transplant patients is not well understood, with current practice suggesting the avoidance of narcotics among transplant…
2021 American Transplant Congress
Peri-covid Trends on the Intestinal Transplant Waiting List
M. L. Samoylova¹, S. Jafri², M. I. Fiel³, S. Horslen⁴, A. Mavis⁵, T. Schiano⁶, B. Summers⁷, M. C. Segovia⁸
¹Surgery, Duke University, Durham, NC, ²Gastroenterology and Hepatology, Henry Ford Hospital, Detroit, MI, ³Pathology, Mount Sinai, New York, NY, ⁴Transplantation, Seattle Children's Hospital, Seattle, WA, ⁵Pediatric Gastroenterology, Duke University, Durham, NC, ⁶Hepatology, Mount Sinai Medical Center, New York, NY, ⁷Pharmacy, Henry Ford Hospital, Detroit, MI, ⁸Gastroenterology, Duke University, Durham, NC
*Purpose: We aim to describe the trends in intestinal and multivisceral transplant waiting list activity and outcomes before and after the COVID-19 pandemic.*Methods: We used…
2021 American Transplant Congress
A Comparison of Pediatric Intestine Transplant Between the Current Era (2015-2019) and the Peak Period (2002-2006)
S. Horslen¹, T. Weaver², M. Skeans²
¹Seattle Children's Hospital, Seattle, WA, ²SRTR, Minneapolis, MN
*Purpose: Demand for intestine transplants in children grew from its clinical inception in the late 1980s to a peak in 2007 of 111 small bowel-containing…
2021 American Transplant Congress
Should We Worry About Covid-19 Infection in Pediatric SOT?
U. Ekong¹, S. Paul¹, S. Royal², J. Chahine³, N. Yazigi¹, S. Kaufman¹, K. Khan¹, C. Matsumoto¹, A. Kroemer¹, T. Fishbein¹
¹Surgery, Medstar Georgetown Transplant Institute, Washington, DC, ²Pediatrics, Medstar Georgetown University Hospital, Washington, DC, ³Pathology and Laboratory Medicine, Medstar Georgetown University Hospital, Washington, DC
*Purpose: We describe the clinical presentation & immune response to COVID-19 infection in pediatric SOT.*Methods: Medical records of COVID-19 PCR+ or seropositive patients were reviewed…
2021 American Transplant Congress
RNA Sequencing (RNAseq) Tissue Analysis Can Provide Early Warning Signals for Potential Intestinal Transplant Complications
J. Kang¹, L. Belyayev¹, O. Aguirre¹, K. Khan¹, Y. Gusev², K. Bhuvaneshwar², H. Ressom³, J. Hawksworth¹, C. Matsumoto¹, T. Fishbein¹, A. Kroemer¹
¹MedStar Georgetown Transplant Institute, Washington, DC, ²Georgetown University Medical Center, Innovation Center for Biomedical Informatics, Washington, DC, ³Georgetown University Medical Center, Lombardi Comprehensive Cancer Center, Washington, DC
*Purpose: A disrupted mucosal barrier in intestinal grafts can cause alloreactive complications such as rejection, inflammation and infection following intestinal transplantation (ITx). We hypothesize that…
2020 American Transplant Congress
A Mouse Model of Paratopic Intestinal Transplantation to Delineate GVHD-Free Alloimmune Rejection Responses
A. Dangi¹, J. Wang², A. Joseph³, J. Roper³, N. Surana⁴, X. Luo¹
¹Nephrology/Medicine, Duke University, Durham, NC, ²Surgery, Duke University, Durham, NC, ³Gastroenterology/Medicine, Duke University, Durham, NC, ⁴Molecular Genetics and Microbiology, Duke University, Durham, NC
*Purpose: Current clinical practice of intestinal transplantation is limited due to a high rate of graft failure and patient mortality. In the present study, we…
2020 American Transplant Congress
Chronic Hyperammonemia an Important Cause of Morbidity in Isolated Intestine Transplant Patients with Venous Outflow to the Vena Cava
R. S. Mangus, C. A. Kubal, T. Burch, B. Ekser, P. Mihaylov, J. Fridell
Indiana University, Indianapolis, IN
*Purpose: There are limited options for superior mesenteric vein (SMV) outflow in isolated intestine transplant (ITx), the two most common being anastomosis to the recipient…
2020 American Transplant Congress
Epidemiology of Clostridioides Difficile Infection in Intestinal and Multivisceral Transplant Patients at a Single Transplant Center
A. Modi¹, B. Gonzalez², K. Brizendine¹
¹Infectious Disease, Cleveland Clinic, Cleveland, OH, ²Pediatric Infectious Disease, Cleveland Clinic, Cleveland, OH
*Purpose: Solid organ transplant (SOT) recipients face increased risk of Clostridioides difficile infection (CDI), with reported CDI incidence of 7.4%-20% far exceeding that of the…
2020 American Transplant Congress
Vascular Complications in Pediatric Intestine Transplant Recipients – Treatment Strategies and Outcomes
A. Amin, Y. Chang, B. Emmanuel, A. Ganoza, G. Bond, A. Khanna, K. Soltys, R. Sindhi, G. Mazariegos
University of Pittsburgh Medical Center, Pittsburgh, PA
*Purpose: To identify vascular complications in pediatric intestine transplant (IT) recipients, evaluate treatment strategies, and review their impact on graft loss and patient mortality.*Methods: Retrospective…
2020 American Transplant Congress
Multicenter Evaluation of Cytomegalovirus Infection Following Intestinal and Multivisceral Transplantation
M. Segovia¹, Y. Patel¹, S. Nagai², D. Sudan¹, S. Jafri²
¹Duke University Hospital, Chapel Hill, NC, ²Henry Ford Hospital, Detroit, MI
*Purpose: Evaluate factors related to incidence and outcomes of cytomegalovirus (CMV) infection after isolated intestinal transplantation (IT) and multivisceral transplantation (MVT).*Methods: Retrospective evaluation of 32…