ATC Abstracts

American Transplant Congress abstracts

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Articles tagged "Inflammation"

  • 2015 American Transplant Congress

    Inflammation in Regions of Tubular Atrophy (IATR) Predicts Adverse Graft Outcome in Patients With Late Graft Dysfunction: A Multicenter Study

    J. Grande,1 R. Leduc,3 A. Matas.2

    1Laboratory Medicine and Pathology, Mayo Clinic, Rochester, MN; 2Surgery, University of Minnesota, Minneapolis, MN; 3Biostatistics, University of Minnesota, Minneapolis, MN.

    Purpose: Inflammation in regions of tubular atrophy (IATR) is a risk factor for late graft loss. However, IATR is associated with inflammation in non-atrophic regions…
  • 2015 American Transplant Congress

    The Effects of Periostin on Renal Fibrosis After Ischemia-Reperfusion Injury Via p38 MAPK Pathway

    J. An,1,2 S. Yang,3 J. Hwang,4 J. Kim,1 S. Kim,2,5 C. Lim,1,2 Y. Oh,1,2 Y. Kim,2 J. Lee.1,2

    1Seoul National University Boramae Medical Center, Seoul, Republic of Korea; 2Seoul National University Hospital, Seoul, Republic of Korea; 3Seoul National University Kidney Research Institute, Seoul, Republic of Korea; 4Chung-Ang University Hospital, Seoul, Republic of Korea; 5Seoul National University Bundang Hospital, Seongnam, Republic of Korea.

    Ischemia-reperfusion injury during the transplantation procedure is associated with poor long-term allograft outcomes, such as rejection and fibrosis. Periostin, a matricellular protein, has been reported…
  • 2015 American Transplant Congress

    Distinctive Roles of mTORC1 Vs. mTORC2 in Liver Ischemia-Reperfusion Injury

    H. Zhou,1,2 J. Zhu,1,3 S. Yue,1 M. Zhang,3 R. Busuttil,1 Q. Xia,3 J. Kupiec-Weglinski,1 Y. Zhai.1

    1The Dumont-UCLA Transplant Center, UCLA, Los Angeles; 2Liver Transplant Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China; 3Liver Surgery, Renji Hospital, Shanghai Jiaotong University, Shanghai, China.

    Mammalian target of rapamycin (mTOR) exists in two complexes to regulate diverse biological processes. Although mTOR complex 1, the canonical target of rapamycin, has been…
  • 2015 American Transplant Congress

    Comparison of Markers of Inflammation Between Dialysis Patients With and Without Failed Kidney Allograft

    R. Villca-Gonzales, R. Vazquez-Apodaca, D. Hernandez-Ramirez, L. Llorente-Peters, J. Alberu, L. Morales-Buenrostro.

    Nephrology and Transplantation, National Institute of Medical Sciences and Nutrition Salvador Zubiran, Mexico City, DF, Mexico.

    BACKGROUND: The rates of morbidity and mortality in patients with a failed kidney transplant are higher than dialysis patients who had never been transplanted. The…
  • 2015 American Transplant Congress

    Neogenin Functions as a Chemokinetic Receptor on Activated CD4+ T Lymphocytes

    L. Boneschansker,1 H. Nakayama,1 M. Eisenga,1 M. Klagsbrun,1 D. Irimia,2 D. Briscoe.1

    1Boston Children's Hospital, Boston; 2Massachusetts General Hospital, Boston.

    Increasing data indicates that axonal guidance cues play a critical role in immunity, both in activation, migration as well as in the process of inflammation…
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