2020 American Transplant Congress
Belatacept Removal by Plasmapheresis: Kinetics, Dose Adjustments and Clinical Recommendations
*Purpose: Belatacept (BELA), a protein immunosuppressant, has limited available pharmacokinetic (PK) data. Available PK data, limited to product development analyses, shows moderate intrapatient variability with…2020 American Transplant Congress
MTOR Inhibitor Management and Wound Complications in Liver Transplant Recipients Undergoing Subsequent Surgeries
Cleveland Clinic, Cleveland, OH
*Purpose: Class-related, concentration-dependent adverse effects associated with mTOR inhibitors (mTORi) include wound complications such as impaired wound healing, incisional hernias, hepatic artery thrombosis, and lymphocele…2020 American Transplant Congress
Is it Time for Immune Screening for Belatacept-Treated Stable Kidney Transplant Patients for Adjust the Immunosuppression?
1ITAC, Buenos Aires, Argentina, 2CEFYBO, UBA, Buenos Aires, Argentina
*Purpose: Belatacept is a co-stimulation blocker for primary maintenance immunosuppression in kidney transplant recipients. The goal of this work was to study the immunological status…2020 American Transplant Congress
Incidence of Rejection One Year after Liver Transplantation Associated with Early versus Late Steroid Withdrawal
The Mount Sinai Hospital, New York, NY
*Purpose: The adverse effects associated with steroid use make earlier steroid withdrawal desirable, but the optimal time for withdrawal after liver transplantation (LT) is not…2020 American Transplant Congress
Perceived Barriers Are Associated with Immunosuppressive Medication Adherence among Japanese Kidney Transplant Recipients: A Cross-Sectional Study
*Purpose: Nonadherence to immunosuppressive medication after kidney transplantation is associated with a high risk of acute rejection and allograft loss. This study aimed to investigate…2020 American Transplant Congress
Clinical Study of Standard versus Reduced Dose Tacrolimus Combined with Generic Mycophenolate Mofetil in De Novo Kidney Transplantation
Department of Surgery, Ajou University Medical School, Suwon, Korea, Republic of
*Purpose: The lowering of calcineurin inhibitor exposure is possibly considered as the proper strategy to prevent calcineurin inhibitor induced nephrotoxicity in kidney transplant. This clinical…2020 American Transplant Congress
Morbidity in Lung Transplant for Connective Tissue Disease
*Purpose: To evaluate the post-lung transplant comorbidities of patients with connective tissue disease (CTD) compared with an age-matched cohort of patients transplanted for idiopathic pulmonary…2020 American Transplant Congress
De Novo Dosing of LCP-Tacrolimus Using Conservative Weight-Based Strategy Resulted in Supratherapeutic Trough Levels in Majority of Patients
University of Virginia Health System, Charlottesville, VA
*Purpose: Due to ongoing national drug shortages, our center transitioned to de novo use of LCP-tacrolimus (LCPT) in kidney transplant patients using a conservative dosing…2020 American Transplant Congress
Evaluation of Pretransplant Serologies and Vaccination Rates in Kidney Transplant Candidates
Department of Pharmacy Services, University of Utah Health, Salt Lake City, UT
*Purpose: Assessing serologic status presents opportunities to provide live vaccinations to solid organ transplant (SOT) candidates. This is especially important given the increased risk of…2020 American Transplant Congress
B Cell Depletion with Anti-CD20 mAb Exacerbates Anti-Donor CD4+ T Cell Responses in Highly Sensitized Transplant Model
Gastroenterological and Transplant Surgery, Hiroshima University, Hiroshima, Japan
*Purpose: Preformed donor-specific anti-human leukocyte antigen antibodies (DSAs) have been associated with detrimental effects in transplant recipients. To eliminate preformed DSAs, we desensitized DSA-positive recipients…
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