2016 American Transplant Congress
Targeting the Constitutively Active PI3K/Akt/mTOR Signaling Pathway in Epstein-Barr Virus B Cell Lymphomas.
Division of Abdominal Transplantation, Stanford School of Medicine, Stanford, CA.
Epstein-Barr virus (EBV) B cell lymphomas in post-transplant lymphoproliferative disorder (PTLD) is a major problem in organ transplantation. Reduction of immunosuppression sometimes result in tumor…2016 American Transplant Congress
Rapamycin Encapsulated Nanoparticles as Pre-Treatment in Lung Transplantation.
Introduction: While short-term lung transplant outcomes have improved over the years, long-term survival rates remain stagnant. Many injuries occur to the donor organ before transplantation,…2016 American Transplant Congress
Everolimus (EVR) versus Mycophenolate Sodium (MPS) for Recipients of Kidney Transplants from Expanded Criteria Donors (ECD) Receiving Anti-Thymocyte Globulin (r-ATG) and Tacrolimus (TAC).
Introduction: There is no standard of care immunosuppressive regimen for recipients of kidneys recovered from expanded criteria donors. Several centers use r-ATG induction due to…2016 American Transplant Congress
The Optimal Time Point for Steroid Withdrawal After Kidney Transplantation Is One Year After Engraftment.
The optimal time of steroid withdrawal after kidney transplantation remains elusive, since RCTs can evaluate one predefined time point. Thus we analyzed all first kidney…2016 American Transplant Congress
Absence of Acute Allograft Rejection in the Early Post Operative Period in a Full Face VCA Recipient with a Positive B-Cell Flow Cytometric Crossmatch Utilizing an Induction Immunosuppression Regimen Including Anti-thymocyte and Anti-CD20 Agents.
Background: The presence of donor-specific antibodies (DSA) to human leukocyte antigen (HLA) convey increased risk of allograft rejection. Patients suffering full-thickness burns to the face…2016 American Transplant Congress
Th17 Development Is Critical for Airway Epithelial Injury After Transplantation.
Department of Immunology, Capital Medical University, Beijing, China.
Background: Development of obliterative bronchiolitis (OB) is the biggest obstacle that limits long-term allograft survival and clinical application of lung transplantation, and the precise mechanisms…2016 American Transplant Congress
Advantages of Computerized Dosing Strategy in Tacrolimus Treatment of Renal Transplant Patients.
Purpose: Tacrolimus (Tac) is widely used in immunosuppression for kidney transplant (KT) patients. Despite this, it is still difficult for expert physicians to achieve and…2016 American Transplant Congress
Factors Predicting Tacrolimus Trough Variability After Lung Transplantation.
The Johns Hopkins Hospital, Baltimore, MD.
Background: Recent data suggests that variability in tacrolimus trough concentrations is associated with acute and chronic rejection. The purpose of this study was to identify…2016 American Transplant Congress
Wound Healing Complications in Kidney Transplant Recipients Receiving Everolimus.
Background: Regimens with de novo everolimus (EVR) are associated with a concentration-dependent incidence of wound healing adverse events (WHAE), but mycophenolate use also is related…2016 American Transplant Congress
Post-Trial Experience with Belatacept: A Large Single Center Experience.
Emory Transplant Center, Atlanta, GA.
Evaluation of belatacept in clinical trials revealed significant improvements in renal function and cardiovascular risk leading to superior survival. Despite these proven benefits higher rates…
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